Adaptive template matching algorithm based on SWAD for robust target tracking

The sum of absolute differences (SAD) is widely used in video coding and disparity computation for its simplicity. However, SAD is not very common in tracking applications owing to issues like partial occlusion and target changes, which can dramatically affect its performance. Presented is a novel adaptive template matching algorithm for target tracking, based on a sum of weighted absolute differences (SWAD). The target template is updated using an infinite impulse response filter, while a weighting kernel is adopted to reduce the effects of partial occlusion. Simulation results demonstrate that the proposed tracker outperforms conventional SAD in terms of efficiency and accuracy, and its performance is comparable with more complex trackers, such as the mean shift algorith

The effect of plant density with different row spacing on quality of the fatty acid composition and grain yield of sunflower

This research was aimed to assess the influence of density with different row spacing on sunflower crop in two different locations in southern Italy. The experiment was laid out in a randomized block design with four replicates. It involved the comparison of sunflower grown in the field on 25 m2-2), obtained by keeping a constant number of plants within the row (3 plants m-1) and varying the spacing between rows (0.4, 0.6 and 0.8 m). In the crops grown at the density of 7.5 plants m-2 (0.4 m row spacing) achene and oil yields were significantly lower as compared to the other treatments. Therefore, the mean values of the two trials did not show any statistical difference between the two densities of 3.75 and 5 plants m-2 (0.8 and 0.6 m row spacing, respectively). However, the superiority in the quality of the fatty acid composition was observed in the crops grown at lower density. Therefore, the row spacing of 0.8 m seems to be a good compromise between achene production and good acid composition of oil.Key words: Helianthus annuus L, plant distribution, plant density, achene yield, oil fatty acid composition

Agricultural quality products for territorial evaluation and tourism development in Sicily: the Pantelleria case

The Agri-Food system is determined and conditioned by the effects of great phenomena, strictly related to territorial, environmental, social, political and economical aspects. Thus, agriculture has to carry out complex roles within the multi-functionality framework throughout production of healthy products, safeguard and protection of environment and territory, preservation and safeguard of bio-diversity, and by supplying goods and services to public, integrating with industry and agrifood distribution. Within such scenery, developed Countries, and in particular those of the EU, carry out strategies in order to adjust to new agrifood market conditions, and to respond to citizens-consumers increasing requests, aiming at quality of agrifood products by recurring to certification marks as a competitive instrument. Rural development becomes the mean to increase industrial and territorial competitiveness in European countries; agriculture is not only linked to industry and distribution, but it undertakes a new role which brings to its integration with tourism, handicraft and the restaurant industry, therefore contributing to the evaluation and to the development of the rural areas. Over 850 certified products are present within the Union, whereas 79.0% of approvals belong to the Mediterranean Area, and where Italy is, with 182 denominations, the richest European country for typical products. Besides these products, it is also necessary to stress the role of wines, them constituting one of the most prominent sectors of the Italian agrifood system, together with the numerous traditional products, still not certified but which, nevertheless, represent a great opportunity for territorial development. Quality products, qualify and reinforce productive and economical local sectors, thus increasing competitiveness and prestige of rural territories. Sicily is, due to the extension of its territory and its population, the biggest Mediterranean island and it boasts with an old agrifood tradition proven true by over 130 typical products, deriving from different agricultural productive fields and from the food handicraft sector . This last is able to trigger a type of tourism that may count upon environmental, naturalistic and the eno-gastronomic patrimony, typical of rural areas and that brings, out of season, touristic request. Within this context, the island of Pantelleria, has been object, during the past twenty years, to radical changes within the socio-economic framework due to the decrease of population territorial abandonment, but mostly because of expertise differentiation, it no longer depending on agricultural activity and by now employed in other sectors, almost all linked to the island’s tourist vocation that has come to being during the second half of the 80s. The greater presence of tourists promotes the development of correlated activities, predominantly constituted by small commercial activities. The acquired visibility brought to the island external capital : investments were put forward on public and private housing as well as on infrastructures able to sustain tourism. Increase of the registered number of houses, starting from last decade, makes Pantelleria an area with an “elevated touristic vocation”. The new touristic flow increases the request of typical local products, and among these, the most required product is “passito di Pantelleria” wine, nowadays also produced by many of the VIPs , owners of homes and lands in Pantelleria. The changes have substantially modified the island’s economy with undoubted benefits for the activities carried out. The turmoil that was therefore recorded for tourism as well as for the more recent wine- wine-growing sector, was not accompanied by an adequate infrastructure development, nor it was favoured by significant public administration measures. The island of Pantelleria represents an example of how the interaction between agriculture and territory brought to life and developed, on the island, in a medium term period, a touristic sector that allowed relaunch of quality wine-growing production

GALNT2 as a novel modulator of adipogenesis and adipocyte insulin signaling

Background/objectives: A better understanding of adipose tissue biology is crucial to tackle insulin resistance and eventually coronary heart disease and diabetes, leading causes of morbidity and mortality worldwide. GALNT2, a GalNAc-transferase, positively modulates insulin signaling in human liver cells by down-regulating ENPP1, an insulin signaling inhibitor. GALNT2 expression is increased in adipose tissue of obese as compared to that of non-obese individuals. Whether this association is secondary to a GALNT2-insulin sensitizing effect exerted also in adipocytes is unknown. We then investigated in mouse 3T3-L1 adipocytes the GALNT2 effect on adipogenesis, insulin signaling and expression levels of both Enpp1 and 72 adipogenesis-related genes. Methods: Stable over-expressing GALNT2 and GFP preadipocytes (T 0 ) were generated. Adipogenesis was induced with (R+) or without (R−) rosiglitazone and investigated after 15 days (T 15 ). Lipid accumulation (by Oil Red-O staining) and intracellular triglycerides (by fluorimetric assay) were measured. Lipid droplets (LD) measures were analyzed at confocal microscope. Gene expression was assessed by RT-PCR and insulin-induced insulin receptor (IR), IRS1, JNK and AKT phosphorylation by Western blot. Results: Lipid accumulation, triglycerides and LD measures progressively increased from T 0 to T 15 R- and furthermore to T 15 R+. Such increases were significantly higher in GALNT2 than in GFP cells so that, as compared to T 15 R+GFP, T 15 R- GALNT2 cells showed similar (intracellular lipid and triglycerides accumulation) or even higher (LD measures, p < 0.01) values. In GALNT2 preadipocytes, insulin-induced IR, IRS1 and AKT activation was higher than that in GFP cells. GALNT2 effect was totally abolished during adipocyte maturation and completely reversed at late stage maturation. Such GALNT2 effect trajectory was paralleled by coordinated changes in the expression of Enpp1 and adipocyte-maturation key genes. Conclusions: GALNT2 is a novel modulator of adipogenesis and related cellular phenotypes, thus becoming a potential target for tackling the obesity epidemics and its devastating sequelae

Methodological approaches to the valuation of forest ecosystem services: An overview of recent international research trends

Forests represent the most important source of ecosystem services (ES) on a global level both for the production of goods and for the provision of services and externalities, nevertheless scientific research in the economic field is lacking. Currently the number of documents relating to ES is 16 673, of which only 1 379 concern the forestry sector. The aim of this study is to provide an overview of scientific research trends in the field of economic evaluation of forest ecosystem services (FES). To this end, an on-line bibliographic survey was carried out on the main scientific search engines, which made it possible to quantify the works and at the same time to detect the main evaluation methods used for the different FES. This survey allowed to collect 93 articles meeting the search criteria: the most active continents were Europe and Asia, whereas most of the articles focused on the joint evaluation of provisioning, regulation and cultural services, even if a good number of them only concerned cultural services. The most widely used valuation methodologies were the contingent valuation among the stated preference techniques and the market price among direct observation criteria

Hepatitis C Virus Evasion Mechanisms from Neutralizing Antibodies

Hepatitis C virus (HCV) represents a major public health problem, affecting 3% of the world’s population. The majority of infected individuals develop chronic hepatitis, which can progress to cirrhosis and hepatocellular carcinoma. To date, a vaccine is not available and current therapy is limited by resistance, adverse effects and high costs. Although it is very well established that cell-mediated immunity is necessary for viral clearance, the importance of host antibodies in clearing HCV infection is being increasingly recognized. Indeed, recent studies indicate that neutralizing antibodies are induced in the early phase of infection by patients who subsequently clear viral infection. Conversely, patients who do not clear the virus develop high titers of neutralizing antibodies during the chronic stage. Surprisingly, these antibodies are not able to control HCV infection. HCV has therefore developed mechanisms to evade immune elimination, allowing it to persist in the majority of infected individuals. A detailed understanding of the mechanisms by which the virus escapes immune surveillance is therefore necessary if novel preventive and therapeutic treatments have to be designed. This review summarizes the current knowledge of the mechanisms used by HCV to evade host neutralizing antibodies

ZnO/ionic liquid catalyzed biodiesel production from renewable and waste lipids as feedstocks

A new protocol for biodiesel production is proposed, based on a binary ZnO/TBAI (TBAI = tetrabutylammonium iodide) catalytic system. Zinc oxide acts as a heterogeneous, bifunctional Lewis acid/base catalyst, while TBAI plays the role of phase transfer agent. Being composed by the bulk form powders, the whole catalyst system proved to be easy to use, without requiring nano-structuration or tedious and costly preparation or pre-activation procedures. In addition, due to the amphoteric properties of ZnO, the catalyst can simultaneously promote transesterification and esterification processes, thus becoming applicable to common vegetable oils (e.g., soybean, jatropha, linseed, etc.) and animal fats (lard and fish oil), but also to waste lipids such as cooking oils (WCOs), highly acidic lipids from oil industry processing, and lipid fractions of municipal sewage sludge. Reusability of the catalyst system together with kinetic (Ea) and thermodynamic parameters of activation (∆G‡ and ∆H‡) are also studied for transesterification reaction

Dermoscopy and methyl aminolevulinate: A study for detection and evaluation of field cancerization

Actinic keratosis (AK) is a keratinocyte intraepidermal neoplasia UV light – induced that frequently appears in sun-exposed areas of the skin. Although historically AK was de fi ned as “ precancerous ” , actually it is considered as the earliest stage of squamous cell carcinoma (SCC) in situ. Since AKs can progress into invasive SCC, their treatment isrecommended. AKsrarely developasa singlelesion;usually multiplelesions commonly affect anen- tire area of chronically actinic damaged skin. This has led to the concept of “ fi eld cancerization ” , an area chroni- cally sun-exposed that surrounds peripherally visible lesions, in which are individualized subclinical alterations. One of the main principles endpoint in the management of AKs is the evaluation and the treatment of fi eld cancerization. In this view, in order to detect and quantify fi eld cancerization, we employed a method based on the topical application of methyl aminolevulinate (MAL) and the detection of the fl uorescence emitted by its metabolite Protoporphyrin IX (PpIX); then, considering the extension and the intensity of measured fl uores- cence, we create a score of fi eld cancerization. The results show that patients underwent to daylight PDT had a reduction of total score, from T0 to T2. Whereas in the group untreated we observed a stability of total score or a slightly worse. So, the method and the score used allows to evaluate with a good approximation the dimension of fi eld cancerization and show the modi fi cation of it after treatment

Resting state functional thalamic connectivity abnormalities in patients with post-stroke sleep apnoea: a pilot case-control study

OBJECTIVE: Sleep apnoea is common after stroke, and has adverse effects on the clinical outcome of affected cases. Its pathophysiological mechanisms are only partially known. Increases in brain connectivity after stroke might influence networks involved in arousal modulation and breathing control. The aim of this study was to investigate the resting state functional MRI thalamic hyper connectivity of stroke patients affected by sleep apnoea (SA) with respect to cases not affected, and to healthy controls (HC). PATIENTS AND METHODS: A series of stabilized strokes were submitted to 3T resting state functional MRI imaging and full polysomnography. The ventral-posterior-lateral thalamic nucleus was used as seed. RESULTS: At the between groups comparison analysis, in SA cases versus HC, the regions significantly hyper-connected with the seed were those encoding noxious threats (frontal eye field, somatosensory association, secondary visual cortices). Comparisons between SA cases versus those without SA, revealed in the former group significantly increased connectivity with regions modulating the response to stimuli independently to their potentiality of threat (prefrontal, primary and somatosensory association, superolateral and medial-inferior temporal, associative and secondary occipital ones). Further significantly functionally hyper connections were documented with regions involved also in the modulation of breathing during sleep (pons, midbrain, cerebellum, posterior cingulate cortices), and in the modulation of breathing response to chemical variations (anterior, posterior and para-hippocampal cingulate cortices). CONCLUSIONS: Our preliminary data support the presence of functional hyper connectivity in thalamic circuits modulating sensorial stimuli, in patients with post-stroke sleep apnoea, possibly influencing both their arousal ability and breathing modulation during sleep

Effects of acoustic features modifications on the perception of dysarthric speech - preliminary study (pitch, intensity and duration modifications)

Marking stress is important in conveying meaning and drawing listener’s attention to specific parts of a message. Extensive research has shown that healthy speakers mark stress using three main acoustic cues; pitch, intensity, and duration. The relationship between acoustic and perception cues is vital in the development of a computer-based tool that aids the therapists in providing effective treatment to people with Dysarthria. It is, therefore, important to investigate the acoustic cues deficiency in dysarthric speech and the potential compensatory techniques needed for effective treatment. In this paper, the relationship between acoustic and perceptive cues in dysarthric speech are investigated. This is achieved by modifying stress marked sentences from 10 speakers with Ataxic dysarthria. Each speaker produced 30 sentences using the 10 Subject-Verb-Object-Adjective (SVOA) structured sentences across three stress conditions. These stress conditions are stress on the initial (S), medial (O) and final (A) target words respectively. To effectively measure the deficiencies in Dysarthria speech, the acoustic features (pitch, intensity, and duration) are modified incrementally. The paper presents the techniques involved in the modification of these acoustic features. The effects of these modifications are analysed based on steps of 25% increments in pitch, intensity and duration. For robustness and validation, 50 untrained listeners participated in the listening experiment. The results and the relationship between acoustic modifications (what is measured) and perception (what is heard) in Dysarthric speech are discussed