Impact of Internet Addiction on Academic Performance of Undergraduate Dental Students of Bhubaneswar, India

Objective: To assess the level of internet addiction and its impact on the academic performance of undergraduate dental students of Bhubaneswar. Material and Methods: A cross-sectional descriptive survey was steered among 814 undergraduate dental students (representing first year through internship) in Bhubaneswar, India. Internet addiction was assessed with the Internet Addiction Test (IAT) developed by Young, which consisted of 20 items rated on a 5-point Likert scale. Google Forms were used to collect the data. Statistical tests like Chi-square, Kruskal-Wallis, and Spearman correlation coefficient were used to analyze the qualitative and quantitative variables, respectively, with the significance level set at p ≤ 0.05. Results: The prevalence of Internet Addiction was found to be 27.5%. Interns showed the highest mean Internet Addiction (57.91±10.71) score. The proportion of addicted students was higher in males, 74 (31.4%), than in females, 150 (26%). The mean scores for individual domains were overuse (16.31±3.64), non-restraints (7.77±2.66), inhibiting the flow of life (9.52±3.05), emotional state (11.25±2.86), and dependence (10.47±2.53). A correlation coefficient (Spearman’s rho value of -.167) indicates a negative correlation between internet addiction and academic scores, which was statistically significant (p=0.001). Conclusion: This study revealed that internet use for varying purposes eventually leads to addiction and affects students’ academic performance. The affected students need early intervention and control over internet usage

Antimicrobial Activity of Soyabean (Glycine max) and Pumpkin Seeds (Cucurbita pepo) Extracts against Common Oral Pathogens: An in vitro Study

Objective: To evaluate the antimicrobial activity of soyabean and pumpkin seeds methanolic extract against oral microbiome. Material and Methods: An in vitro study compared the antimicrobial activity of methanolic extract of soyabean and pumpkin seed along with 0.2% chlorhexidine (positive control) by Agar well diffusion method against Streptococcus mutans, Streptococcus pyogenes, Staphylococcus aureus, Lactobacillus and Candida albicans. Suitable dilutions of each seed extract determined Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC). Qualitative phytochemical analysis and Thin Layer Chromatography (TLC) was done to determine the phytochemical components. Results: Both the methanolic extracts showed the highest zone of inhibition, 26±0.31 mm and 24±0.82 mm, followed by 22±0.87 mm and 21±0.55 mm against Streptococcus mutans and Streptococcus pyogenes, respectively. The zone of inhibition was higher at concentrations in both extracts, which was not statistically significant (p>0.05). MIC values fluctuated from 1.56 to 4.5 mg/ml and 3.5 to 5.0 mg/ml for soyabean and pumpkin seed extract, respectively. Phytochemical analysis showed the presence of alkaloids, glycosides, terpenoids, tannins, and flavonoids. Conclusion: Both extracts were effective against S. mutans and S. pyogenes and contain compounds with therapeutic potential

Remodelación de la odontología y las tecnologías dentales después de la enfermedad por coronavirus 2019 (COVID-19).

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The economic synthesis of pyridinium fluorochromate(VI), C<SUB>5</SUB>H<SUB>5</SUB>NH[CrO<SUB>3</SUB>F] (PFC), and solvent-free oxidation of organic substrates with PFC

A 1:1:1 stoichiometric reaction among CrO3, aqueous HF and pyridine affords orange crystalline pyridinium fluorochromate(VI), C5H5NH[CrO3F] (PFC), in 99.2% isolated yield. The reagent under solvent-free conditions readily converts benzylic, secondary, and allylic alcohols to the corresponding carbonyls and selectively oxidizes secondary alcohols in the presence of primary alcohols, polycyclic hydrocarbons to cyclic ketones, benzoin to benzil, PPh3 to O=PPh3, methylphenyl sulfide to sulfoxide, cyclohexanone oxime to cyclohexanone, an allylic &#916;5-steroid to the corresponding &#945;,&#946;-unsaturated ketone and deprotects dioxolanes and dithiolanes to aldehydes; the economic synthesis of PFC, its ease of reaction without solvent, versatility, and high isolated yields of the products are the significant features of the protocol

Temporal Trends of Exposure to Phthalates and Phthalate Alternatives in California Pregnant Women during 2007–2013: Comparison with Other Populations

Phthalates with potential adverse health effects are being replaced by other phthalates or phthalate alternatives. Little is known about temporal trends of phthalate exposure in pregnant women in the United States. We quantified 16 metabolites of eight phthalates and di(isononyl) cyclohexane-1,2-dicarboxylate (DINCH) in 656 urine samples collected from 192 California pregnant women in 2007-2013 during their second and third trimesters of pregnancy who participated in the MARBLES (Markers of Autism Risk in Babies-Learning Early Signs) study. We used multiple regression to estimate least squares geometric means of phthalate biomarker concentrations and annual percent changes over the study period. Biomarker concentrations of diethyl phthalate (DEP) and three phthalates with known toxicity and adverse health effects (i.e., butyl benzyl phthalate [BBzP], dibutyl phthalate [DBP], di(2-ethylhexyl) phthalate [DEHP]) decreased, while those of di-isobutyl phthalate [DiBP], di-isononyl phthalate [DiNP], and di-n-octyl phthalate [DOP] increased in California pregnant women during our study period. To understand broad social forces that may influence temporal trends and geographic variations in phthalate exposure across countries, we compared our phthalate biomarker concentrations with those of other populations. We observed over a factor of 2 differences in exposure across countries for some phthalate biomarkers and between pregnant and nonpregnant women for DEP

Regioselective bromination of organic substrates by tetrabutylammonium bromide promoted by V<SUB>2</SUB>O<SUB>5</SUB>-H<SUB>2</SUB>O<SUB>2</SUB>: an environmentally favorable synthetic protocol

Vanadium pentoxide very effectively promotes the bromination of organic substrates, including selective bromination of some aromatics, by tetrabutylammonium bromide in the presence of hydrogen peroxide; mild conditions, high selectivity, yield, and reaction rate, and redundancy of bromine and hydrobromic acid are some of the major advantages of the synthetic protocol

Dengue-specific subviral nanoparticles: design, creation and characterization.

Dengue is today the most significant of arboviral diseases. Novel tools are necessary to effectively address the problem of dengue. Virus-like particles (VLP) offer a versatile nanoscale platform for developing tools with potential biomedical applications. From the perspective of a potentially useful dengue-specific tool, the dengue virus envelope protein domain III (EDIII), endowed with serotype-specificity, host receptor recognition and the capacity to elicit virus-neutralizing antibodies, is an attractive candidate

Dengue-specific subviral nanoparticles: design, creation and characterization

Abstract Background Dengue is today the most significant of arboviral diseases. Novel tools are necessary to effectively address the problem of dengue. Virus-like particles (VLP) offer a versatile nanoscale platform for developing tools with potential biomedical applications. From the perspective of a potentially useful dengue-specific tool, the dengue virus envelope protein domain III (EDIII), endowed with serotype-specificity, host receptor recognition and the capacity to elicit virus-neutralizing antibodies, is an attractive candidate. Methods We have developed a strategy to co-express and co-purify Hepatitis B virus surface (S) antigen in two forms: independently and as a fusion with EDIII. We characterized these physically and functionally. Results The two forms of the S antigen associate into VLPs. The ability of these to display EDIII in a functionally accessible manner is dependent upon the relative levels of the two forms of the S antigen. Mosaic VLPs containing the fused and un-fused components in 1:4 ratio displayed maximal functional competence. Conclusions VLPs armed with EDIII may be potentially useful in diagnostic, therapeutic and prophylactic applications