Analysis of Compost Parameters and a Molecular Approach on its Thermophilic Microflora

Abstract- The present study deals on factors and parameters influencing composting. The temperature, pH, ash, moisture, carbon and nitrogen content estimated at every 15 days interval states that composting is high during thermophilic phase than mesophilic phase. The microbial loads of bacteria were estimated by SPC method in PBYG medium. charecterization was done by biochemical analysis, thermotolerance assay and by molecular methods. Amplification of 16s rRNA gene sequence and universal eubacterial primers 27F and 1492 R to give a product of approximately 1500 bp in length was amplified by PCR. Sequencing software windows VQ2, gene codes were used to assemble the fragment. The sequence data was analyzed by comparing in gene bank database using Basic local Alignment Search Tool (BLAST 2.2.1.6) in a nucleotide to nucleotide search of 16s rRNA gene sequence from type strain and species were identified as thermophilic Bacillus pumilis and Pseudomonas stutzeri showing 93 % and 98 % homology respectively. T Index Terms- Thermophiles, Compost, Composting Analysi

3D QSAR studies of synthetic compounds as potential inhibitors for Anti - hyperglycemic targets.

 Background: The identification of potential compounds for an anti-hyperglycemic makes real challenges in the pharmaceutical industry. Library ofcompounds have introduced so far, but identifying the specific target, which makes more sensation.Objective: In the present study, the quantitative structure-activity relationship (QSAR) studies have been analyzed from the compounds wereretrieved from online and literature survey.Methods: The compound, 6, 7, 8, 9-tetrahydro-2h-11-oxa-2, 4, 10-triaza-benzo [b] fluoren-1-one has taken as a potential target to perform QSARstudy based on the principle of the molecular docking analysis and pharmacophoric features. QSAR models were generated a target from the first 10potential targets in the training set.Results: The predictive ability of both models was determined using a randomly chosen test set gave predictive correlation coefficients of r2=0.9.Conclusion: This analysis shows the ADNRR shows very close to the interactions recorded in the active site of the ligand bound complex.Keywords: Quantitative structure-activity relationship, Pharmacophore Alignment and Scoring Engine, Dipeptidyl peptidase 4, Anti-hyperglycemictargets, Docking studies, Three dimensional quantitative structure-activity relationship

Searching and locating OER: Barriers to the wider adoption of OER for teaching in Asia

Abstract Open Educational Resources (OER) are fast becoming a global phenomenon which could potentially provide free access to knowledge for the masses. Since the inception of this concept, governmental and non-governmental grants alongside generous philanthropy have given rise to a vast array of OER repositories all over the world. With this movement gaining momentum, more and more of the learned community have started contributing resources to these OER repositories making them grow exponentially rich in knowledge. However, despite the availability of a large number of OER repositories, the use and re-use of OER are yet to become mainstream in many regions and institutions. One reason for this slow uptake is the inability to effectively search and locate desirable OER using the available search methodologies as it would be next to impossible to trawl through all the disconnected and disparate repositories manually. The findings discussed in this paper are part of a broader study into the OER landscape in the Asian region concentrating mainly on China, Hong Kong, India, Indonesia, Japan, South Korea, Malaysia, Philippines and Vietnam where close to five hundred and eighty academics from public, private notfor-profit and private for-profit institutions participated. This research paper discusses how Asia fares with respect to searching and locating desirable OER and whether it is truly a barrier to the wider adoption of OER for teaching in the region

Natrinai Based on the Narrative Songs of Tholkaappiyam

Tolkaappiyam is a comprehensive text on grammar which contains total 1610 sutras in the nurpa meter, it contains three books such as letters, words and subject matter. Tholkaappiyar has explained about the various types of claims both internal and external in subject matter.  In particular, he points out the narration in the 15th song out of 34 songs. This article explains the way in which Natrinai songs are composed with special interpretations called narrations. M.S. Rabising explains narrations as follows. A narration where one of the characters is speaking directly to the audience is called poetry.  Subjective songs are classified as ``Talaivan Kootru'', a song that sounds like a boy speaking, and ``Thozhi Kootru'', a song that sounds like a friend speaking.  In Tiruvalluvar's Kamathuppal, this type of narration or conversationis very famous.  In subjective literature, the hero and the heroine are the main character for narration. Therefore, this article reveals the manner in which the narrators follow the internal norms by analyzing the hymns from the perspective of the performers during the times of love making