A CROSS-SECTIONAL STUDY TO ESTIMATE THE PREVALENCE OF HYPERTENSION IN URBAN FIELD PRACTICE AREA OF MEDICAL COLLEGE IN METROPOLITAN CITY OF INDIA

Objectives: The objectives of the study were to estimate the prevalence of hypertension in people above 35 years and to study the sociodemographic profile of the study subjects. Methods: The study was a cross-sectional study conducted in urban field practice area of medical college. Five chawls were selected by simple random sampling out of 42 chawls. Males and females above 35 years of age living in study area formed a sample frame. Sample size was calculated and it was 667. As per the protocol, informed written consent and demographic details with clinical data were obtained from the patients. Results: A total of 667 participants were included from five chawls. Maximum number of participants, that is, 37%; were from the age group of 35 to 44, consisting of 41% males and 59% females. Around 67% of study respondents belonged to the age group of 35–54 years. Around 3/4th of study respondents had studied up to primary school and secondary and high school. Out of 263 males, 37%, that is, 98 respondents were hypertensive, and out of 404 females, 152, that is, 38% were hypertensive. Hence, the total prevalence of hypertension in this study was 37.5%. Conclusion: Hypertension is the new era pandemic which is the leading cause of morbidity and mortality in the world and is ranked third as a cause of disability-adjusted life years. To control hypertension, it is imperative to identify and modify its risk factors

Role of 0.5 M mannitol as an adjuvant with lidocaine with or without epinephrine for inferior alveolar nerve block : a randomized control trial

Background: The most commonly used local anesthetic in dentistry is lidocaine. For decades, mannitol is the most widely used agent in the management of raised intracranial pressure and as prophylaxis against acute renal failure surgeries. Material and Methods: 120 patients were randomly divided into four groups, 30 patients in each group. Group A was administered 2% lidocaine with 1:80000 epinephrine; group B, 2% lidocaine with 1:80000 epinephrine and 0.5 M mannitol; group C, 2% lidocaine and 0.5 M mannitol; and group D (control group), 2% lidocaine for achieving local anesthesia. Extraction of lower erupted tooth was done under inferior alveolar nerve block. Parameters taken were onset of anesthesia, duration of anesthesia and pain. Heft-Parker visual analogue scale was taken to evaluate the pain response during procedure after every 10 minutes until complete return of sensation by probing. The Chi-square test was used to compare the pain among the groups. The continuous variables were compared among the groups by one way analysis of variance (ANOVA) followed by Tukey?s post-hoc comparison tests. The p-value 0.05). The total time in return of sensation was higher among the patients of group C (70.30±4.34) than group A (65.94±3.45), group B (62.23±7.47) and group D (47.70±8.04) but difference among the groups was found to be statistically significant (p=0.0001). There was no significant (p>0.05) difference in the pain at baseline and at start. No pain was found among all the patients from 10 minutes to subsequent time intervals. Conclusions: Mannitol was effective in increasing the efficacy of lidocaine as an adjuvant to local anesthetic solution in inferior alveolar nerve block

Simulation of Field Oriented Control Variable Frequency Induction Motor Drive

now days replacing the DC motor with Induction motors are requirement of each plant due to very high operating cost associated with DC motors. To achieve the better dynamic response like as DC motors IM drives are developed. Field Oriented Control based drives with pulse width modulation technique for operation of inverter. In field oriented control method whole induction motor is converted into mathematical DC motor model and control like a dc motor. by Feedback control loop system a gate pulse is generated for the pulse width modulated inverter and according to that voltage and frequency to be controlled. These new technique improve the torque speed characteristics and reduced the response time. This results a very good speed controlling of induction motor and required speed torque characteristic

Nutritional assessment of rural children (6–12 years) of north bihar: A cross-sectional study

Objective: Malnutrition is one of the most common causes of morbidity and mortality among children and adolescent throughout the world. The present study was undertaken to assess the nutritional status in terms of the prevalence of stunting and thinness among rural children of North Bihar. Methods: The present community-based cross-sectional study was conducted on 1263 rural children (674 male and 589 female) with the age group of 6–12 years, during the period from January 2018 to March 2018. Age was recorded in completed year; height and weight were measured in centimeter and kilogram, respectively. Body mass index (BMI) was calculated using standard equation. Results: The nutritional status in terms of the prevalence of stunting and thinness was found to be 18.2% and 23.8%, respectively, among studied children. Stunting was significantly higher among girls (23.1%) in comparison to boys (13.9%). BMI was significantly associated with age, socioeconomic status and mother’s literacy. Conclusions: Anthropometric assessment indicates that the malnutrition is still a major problem among children (6–12 years) of North Bihar. The major factors identified for this problem is illiteracy of mother and socioeconomic status of the family

Economic losses due to important diseases of bovines in central India

Aim: To analyze the factors associated with morbidity and mortality rates as well as to evaluate economic losses due to important diseases of bovines, viz. mastitis, HS and surra in Purvanchal Region of Uttar Pradesh. Materials and Methods: A sample of 300 livestock owners were selected from each of five divisions of Purvanchal region of the state of Uttar Pradesh using multistage stratified sampling with simple random sampling without replacement at village level. The morbidity, mortality and case fatality rates due to different diseases were determined using standard statistical indices. Association between cattle morbidity and mortality rates and different factors was calculated by χ2 Test. The total economic loss due to diseases in bovines was worked out as sum of mortality loss, loss in milk yield and cost of treatment of affected animals. Results: The overall morbidity rates of mastitis, HS and surra in cattle and buffaloes were 15.5%, 7.1% and 5.3%, respectively. The mortality and case fatality due to HS was found higher in the young calves as compared to the adults in case of both buffaloes and cattle. Mortality and case fatality due to surra was greater in the adult animals as compared to the younger ones in case of both buffaloes and cattle. Total losses due to mastitis per lactation in ND cow, CB cow and buffalo were INR 868.34, INR 1, 314.10 and INR 1, 272.36, respectively. Total losses due to HS per animal in ND cows, CB cows and buffaloes were INR 2, 355.78, INR 3, 228.52 and INR 4, 262.57, respectively. Total losses due to surra per animal in ND cow, CB cow and buffalo were INR 3, 328.18, INR 6, 193 and INR 9, 872.33, respectively. Conclusion: The study thus revealed significant losses due to diseases in large ruminants on. There is thus ample scope for preventive measures to control the disease bovines

Comparative Study to Evaluate the Efficacy and Safety of Propranolol versus Amitriptyline for Prophylaxis of Migraine

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Hepatotoxicity of Microcystis aeruginosa Strains Growing as Blooms in Certain Eutrophic Ponds

Critical assessment of five eutrophicated ponds of Varanasi city (India) revealed the presence of heavy blooms of cyanobacteria consisting mainly of Microcystis aeruginosa. Crude aqueous extracts of blooms as well as laboratory grown M. aeruginosa isolated from three ponds, namely Lakshmikund, Durgakund and Adityanagar showed toxicity in mouse bioassay test. Crude aqueous extracts from these samples caused death of test mice within 1h of administration (i.p.) with a LD50 of 60 mg/kg body weight and the treated animals showed clinical signs of hepatotoxicity. However such an effect was not associated with the blooms from Laatbhairov and Surajkund ponds suggesting that not all strains of M. aeruginosa are toxic. Based on spectral properties (?max 230 nm), and comparison with standard microcystin-LR, the toxin is tentatively identified as microcystin-LR. The purified toxin caused death of test mice within 40 min of its administration with a LD50 of 100 µg/ kg body weight and induced gross morphological and functional changes in liver. A 1.55 fold increase in liver weight accompanied by deep red coloration most probably due to hemorrhage and blood pooling suggested the hepatotoxic properties of the toxin. Hepatotoxicity was also evident from the drastic increase (up to 2.5 fold) in activity of serum enzymes such as glutamate pyruvate transaminase/alanine aminotransferase (GPT/ALT), lactate dehydrogenase (LDH) and alkaline phosphatase (APase) following toxin treatment. ^14C-labelling experiments demonstrated maximum accumulation (~15%) of ^14C- toxin after 20 min. of toxin administration. Appreciable level of toxin was also detected in water of four ponds. In conclusion these results clearly demonstrate that microcystin-producing blooms of M. aeruginosa are common in eutrophicated ponds of Varanasi city but not all ponds harbour toxic blooms

Effect of Sertraline on biomarker alterations in patients of multidrug resistant tuberculosis with depression: a prospective clinical trial

Background: Lipid profile parameters may be used as biomarker for depression. Sertraline belongs to selective serotonin reuptake inhibitors (SSRIs), the most commonly used group to treat the depression in multidrug resistant tuberculosis patients.Methods: A prospective clinical trial was carried out in department of Psychiatry and department of Tuberculosis and Respiratory disease G.S.V.M. Medical College, Kanpur. Diagnosed MDR TB patients were screened for depression applying Hamilton Depression Rating Scale (HDRS) and these patients were referred to Psychiatrist for diagnosis of depression. Total 25 diagnosed patients of MDR TB with mild to moderate depression were selected. HDRS Score and morning blood sample of 5ml were collected to analyze biomarker for depression before intervention. Same test was repeated in 18 patients who completed the study at day 30 and 120 after administering Sertraline (50mg). Data were compiled and analyzed using SPSS 20.0 and paired t - test.Results: The mean decrease in HDRS score from base line at day 30 and 120 of administering Sertraline were 6.22 (±1.26) and 2.72 (±0.67) which were significant (p˂0.001). The mean increase in serum cholesterol at day 30 was 153.94 (±19.31) and at day 120 was 157.83 (±19.36) which were significant (p˂0.001). Rest of Tg, HDLc, LDLc and VLDL cholesterole levels were not increased significantly.Conclusions: As the depression symptoms improved by sertraline. The biomarkers of depression were also increased (within the normal range) from baseline but significant increase was observed in serum cholesterol only

Uncertainties in Bistatic RCS Measurements

Radar Cross Section (RCS) is a far field parameter and limited test range length produces error in its measurements. RCS measured with co-located Tx and Rx antennas is termed as monostatic RCS and with spatially separated Tx and Rx antennas as Bistatic RCS (BRCS). Interest in BRCS measurements has grown due to increase in use of multi-static Radars for detecting low-observable targets. In literature BRCS measurement techniques explored are either horn antenna based far field setups or Compact Antenna Test Range (CATR) based setups. All the techniques have inherent limitations and errors, which need to be assessed as the information generated plays a decisive role in the design of military platforms. In the present paper, the errors in each measurement technique are obtained through extensive numerical computation and measurements on various canonical as well as complex shapes. The results highlight the effect of the phase curvature in either or both, Tx, and Rx paths, affect the measurement accuracies, thereby limiting the target size and highest frequency of operation of present techniques

Process intensification for the small footprint compact heat transfer device

Process intensification for the development of compact heat exchanger with small footprint is greatest challenge of the heat exchanger technology today. In the present study, a heat transfer device, coiled flow inverter (CFI) is revamped for the better heat transfer efficiency with a smaller footprint. The proposed small foot-print coiled flow inverter (SFCFI) is fabricated by bending of helical coil at 90° with equal arm lengths before and after the bend with variable curvature radius. In integration to the improved centrifugal force due to variable curvature, the SFCFI additionally offers a complete 90 flow inversion caused by each 90 bend, which results in higher radial mixing and heat transfer. The velocity and temperature flow fields depict the improved radial mixing under the laminar flow regime for the Dean number ranges from 8 to 1581. The performance of existing CFI of same heat transfer area (0.17 m2) was studied and compared with the novel SFCFI device. The results suggest, the proposed SFCFI device provides three-fold heat transfer enhancement as compared to the straight tube of same heat transfer area at Dean number 400. Additionally, heat transfer coefficient in SFCFI enhanced by 48 % as compared to helical coil. Furthermore, SFCFI provides 18 % higher value of Nusselt number as compared to the CFI. The reason for improved heat transfer may be the enhanced centrifugal force due to additional curvature effect provided in each arm of SFCFI in the plane of vortex formation. It was interesting to note that the proposed device provides 11 % lower pressure drop as compared to the CFI. The present study may aids to the development of a novel design of compact coiled and small footprint heat transfer device.Papers presented at the 13th International Conference on Heat Transfer, Fluid Mechanics and Thermodynamics, Portoroz, Slovenia on 17-19 July 2017 .International centre for heat and mass transfer.American society of thermal and fluids engineers