A Novel Technique of Using Touch and Keystroke Dynamics for Sequential Authentication on Smartphones

Smartphones are now more of a requirement than an accessory in the modern world. Thanks to all of the applications on the smartphone, it has evolved into our personal assistant. Every smartphone user is concerned about mobile security because they conduct a variety of transactions on their phones and store sensitive data there. Passwords can be stolen via finger oil or shoulder surfing, so password authentication is not really a more reliable authentication method. Sequential or continuous authentication on smart devices, touch and keystroke dynamics are behavioral biometric authentication techniques that use the user's typing and touching patterns to confirm their identity continuously. For all smart devices, the authors of this study suggested a TKDSmart system to improve authentication. The TKDSmart system's authenticity was confirmed by the EER 4.1 percent, FRR 6.73 percent, and FAR 1.66 percent, that were systematically proved

Performance Analysis of Network Coding with Exponential back off Algorithm Using Multi Path Transfer Protocol in Wireless Network

Network coding is an effective technique to boost the capacity of wireless networks. In that network, transmitted data is encoded and decoded to increase network throughput and to reduce end to end delay and make the network more robust. In this paper, the throughput and end to end delay of network coding is investigated under IEEE802.11 DCF. It is proposed that this can be achieved with CSMA/CA as in IEEE802.11 distributed coordination function with Multi Path Transfer Protocol (DCF-MPTP). CSMA/CA is based on the combination of physical carrier sensing and exponential back off algorithm. Proposed model prevents the delay and packed loss

Determination of bioanalytical parameters for the standardization of Abroma augusta

AbstractObjectiveTo set the analytical parameters for simultaneous determination of different phytochemicals present in the Abroma augusta (A. augusta).MethodsDifferent phytochemical test including total phenol and total flavonoid content were carried out in the present investigation. Further, a rapid and simple high-performance thin-layer chromatographic (HPTLC) method was developed for the qualitative and quantitative analysis. Moreover antimicrobial study was also performed in the present investigation to know the presence of biological contamination.ResultsPreliminary phytochemical analysis revealed the presence of glycoside, alkaloid, carbohydrate and steroid in the A. augusta. Total phenol and total flavonoid content were found to be 0.29% and 0.50% w/w respectively. All tested microorganism in the A. augusta extract were found to be under the limit. Chloroform: methanol: acetic acid: H2O (170:25:25:4) was used as a solvent system for the qualitative and quantitative analysis through HPTLC Method. HPTLC analysis revealed 1.87 % w/w of linoleic acid in the A. augusta extract.ConclusionsResults showed that the selected parameters in the present investigation would set the new standards for the qualitative and quantitative analysis of A. augusta

Formulation and Evaluation of Transdermal Delivery System Comprising Captopril as Antihypertensive Drug

Eventually, based on results of various evaluation parameters like thickness, strength, elongation, better compatibility and stability the transdermal matrix patches was successfully designed and developed by trial and error method. Formulations were prepared by employing combination of HPMCK15M, PVPK30, and EC in various ratios. From the research, various conclusions were drawn. The patches showed good thickness, tensile strength and content uniformity of drug. The used polymers (HPMCK15M, PVPK30, and EC in various ratios) employed to design transdermal patches in different proportion. Invitro release from transdermal patches showed extended release of drug for 24 hours. From the result of present experimental investigation, the formulation F4 showed good results on evaluation studies. Hence F4 formulation were the Optimized formulation. The Captopril penetration from formulated transdermal patches was found to follow diffusion mechanism and obeys zero order release. So we can conclude that transdermal delivery system would be used as drug carrier for Captopril

Inhibition of angiogenesis and tumour growth by VEGF121–toxin conjugate: differential effect on proliferating endothelial cells

Vascular endothelial growth factor (VEGF) plays an important role in tumour angiogenesis. VEGF binds to tyrosine kinase receptors, which are expressed almost exclusively on tumour endothelium. Therefore, VEGF can be used to target toxin molecules to tumour vessels for anti-angiogenic therapy. However, recent evidence suggests that VEGF can also bind in an isoform-specific fashion to a newly identified neuropilin-1 (NP-1) receptor. NP-1 is widely expressed in normal tissue and presents a potential target for unwanted toxicity. As a consequence, we investigated whether the VEGF121 isoform, which lacks the NP-1 binding domain, could be used to target toxin polypeptides to tumour vasculature. Treatment of endothelial cells with a VEGF121–diphtheria toxin (DT385) conjugate selectively inhibited proliferating endothelial cells, whereas confluent cultures were completely resistant to the construct. In addition, VEGF121–DT385 conjugate treatment completely prevented tumour cell induced angiogenesis in vivo. Most importantly, the conjugate inhibited tumour growth in athymic mice and induced tumour-specific vascular damage. There was also no apparent toxicity associated with the treatment. Our results suggest that proliferating endothelial cells are highly sensitive to VEGF121–toxin conjugates and that the binding to NP-1 receptors is not necessary for efficient inhibition of tumour growth. © 2000 Cancer Research Campaig

NATURAL PRODUCTS AS AN IMPORTANT LEADS FOR DISCOVERY OF NEW ANTITUBERCULAR AGENTS: A REVIEW

There is a very much need for a discovery of new molecules a potent molecule that can cure tuberculosis and prevent the recurrence. A multidisciplinary approach is required to procure a potent bioactive compound and this includes expertise in the fields of ethnobotany, ethnopharmacology and Phytochemistry. The present communication acts as a bioprospecting source for the drug discovery against tuberculosis, including several anti tubercular agents which is used by used by tribal people and prescribed by THPS which showed a good inhibition rate. Therefore, this review strives to describe the literature on the traditional plants/potent molecules those have been proved to have antimicrobial activity and to provide essential discussion and accelerate the research.Â

PERFORMANCE ANALYSIS OF NETWORK CODING WITH IEEE802.11 DCF USING MULTI PATH TRANSFR PROTOCOL IN WIRELESS NETWORK

In this paper investigated the throughput and end to end delay of network coding under IEEE802.11 Distributed coordination Function (DCF). In this paper proposed the random medium access of CSMA/CA   as in IEEE802.11 distributed coordination function with Multi Path Transfer Protocol (DCF-MPTP). In an CSMA/CA is based on the combination of physical carrier sensing and exponential back off algorithm and then formulate the probability of successful transmission, collision probability and the re-transmission mechanism. In our model multi hop network used the MPTP (protocol) it prevent the delay and packed loss of source to destination. Finally use computer simulation to verify an analytical  model

WILL THE TRADITIONAL MEDICINE UN-PAUSE THE WORLD AND DECIDE THE FATE OF COVID-19?

COVID-19 is a life-threatening disease that mainly affects the human respiratory system. In today’s world, scientists are working conscientiously for the identification of promising drugs and vaccines. But, when we look back to the former times, herbal medicines were considered for curing most of the diseases; luckily, nowadays, natural remedies are being carried forward by few researchers even for the treatment of most life-threatening diseases like cancer, diabetes and alzheimer’s etc. So, why can't we attempt the herbal formulation for the management of COVID-19 too? Since there is no proper scientific validation for traditional herbs and spices; it just can’t be simply ignored. When a product with less or few side effects can be prepared and made available for the benefit of people, there is nothing wrong in pondering them. Thus, keeping these points in mind, in this article, we have discussed about SARS CoV-2, their treatment options and the impact of natural remedies on both the former as well as novel coronavirus. Further, we have also emphasized on traditional Chinese medicine, various flavonoids and kabasura kudineer and their impact on coronavirus infection. Till now, there is no particular drug or vaccine available for the treatment of COVID-19; thus prevention is the only option. But, we hope that thorough study; screening, preclinical and clinical evaluation of natural compounds may give some action against SARS CoV-2. Moreover, incorporating natural herbs and spices in our diet can help in boosting immunity and fight against various life-threatening diseases