450 research outputs found
Towards a pragmatic approach for dealing with uncertainties in water management practice
Management of water resources is afflicted with uncertainties. Nowadays it is facing more and new uncertainties since pace and dimension of changes (e.g. climatic, demographic) are accelerating and are likely to increase even more in the future. Hence it is crucial to find pragmatic ways to deal with these uncertainties in water management. So far, decision-making under uncertainty in water management is based on either intuition, heuristics and experience of water managers or on expert assessments all of which are only of limited use for water managers in practice. We argue for an analytical yet pragmatic approach to enable practitioners to deal with uncertainties in a more explicit and systematic way and allow for better informed decisions. Our approach is based on the concept of framing, referring to the different ways in which people make sense of the world and of the uncertainties. We applied and tested recently developed parameters that aim to shed light on the framing of uncertainty in two sub-basins of the Rhine. We present and discuss the results of a series of stakeholder interactions in the two basins aimed at developing strategies for improving dealing with uncertainties. The strategies are synthesized in a cross-checking list based on the uncertainty framing parameters as a hands-on tool for systematically identifying improvement options when dealing with uncertainty in water management practice. We conclude with suggestions for testing the developed check-list as a tool for decision aid in water management practice. Key words: water management, future uncertainties, framing of uncertainties, hands-on decision aid, tools for practice, robust strategies, social learnin
Characterization of Proton Transfer Reaction Mass Spectrometry for the detection of sesquiterpenes
Sexual violence in medical students and specialty registrars in Flanders, Belgium : a population survey
Background: Sexual violence has globally been recognized as harmful to young people’s health. In medical school,
which is a highly competitive environment, the risk is supposedly even bigger. In this study we firstly aimed to
investigate the magnitude and precipitating factors of sexual violence in medical students and specialty registrars in
Flanders, Belgium. Secondly, we wanted to assess the reactive behaviours as well as the knowledge of possible
types of bystander reactions as well as potential support resources for victims of sexual violence.
Methods: This study was initiated and coordinated by the Flemish medical student representation organisation
(VGSO). A survey containing demographic and behaviour-specific questions based on the UNMENAMAIS and SAS-V
questionnaire was sent to all undergraduate, graduate and postgraduate students of the 5 medical schools in
Flanders. Participants were asked to limit their responses to internship-related events. Further questions concerning
reactions to sexual violence, assailants, bystander reactions and general knowledge concerning support after sexual
violence were asked.
Results: We received 3015 valid responses to our survey, obtaining a response rate of 29% in the potential target
population. Within the total study population, 1168 of 3015 participants (38,73%) reported having been victim of at
least one type of sexual violence as explored by our survey. This percentage was the highest in GP specialty
registrars (53%), followed by specialty registrars (50%) and master students (39%). Assailants of sexual violence
varied, most often they were medical staff members, students or patients. In most types of sexual violence, nobody
reacted to this behaviour. Women (57.3%) talked about what happened afterwards more often than men (39.7%).
When asked about their knowledge of possible bystander reactions and support services for sexual violence, 60% of
the respondents did not know about their existence.
Conclusions: Sexual violence is still a relatively frequent issue in medical students and specialty registrars. Patients
form an important part of the assailants. In a third of reported sexual violence cases, nobody reacted. In addition,
male victims seem to underreport. There is still much need for sensitisation on support mechanisms and centres for
victims and witnesses of sexual violence
Classification and management of allergic rhinitis patients in general practice during pollen season
Background: Allergic rhinitis (AR) represents a major challenge in primary care. The Allergic Rhinitis and its Impact on Asthma (ARIA) group proposed a new classification for AR and developed evidence-based guidelines for the management of this disease. We conducted this study to further characterize the classes of AR described by ARIA, and to evaluate whether the management of AR in general practice is in accordance with the ARIA guidelines.
Methods: During the pollen season of 2003, 95 Belgian general practitioners (GPs) enrolled 804 patients who presented with symptoms of AR. For each patient, a questionnaire comprising the clinical presentation and management was completed.
Results: In 64% of the patients, AR was classified as intermittent and in 36% as persistent. Persistent rhinitis caused more discomfort than intermittent rhinitis. Only 50% of the patients had ever undergone allergy testing. Among them, 51% were allergic to both seasonal and perennial allergens. Eighty-two per cent of the persistent rhinitics were allergic to at least one seasonal allergen and 72% of the intermittent rhinitics to at least one perennial allergen. When compared strictly with the ARIA recommendations, 49% of the patients with mild and/or intermittent AR were overtreated, whereas about 30% of those with moderate/severe persistent rhinitis were undertreated.
Conclusion: This study confirms that the previous classification of AR into 'seasonal' and 'perennial' is not satisfactory and that intermittent and persistent AR are not equivalent to seasonal and perennial AR respectively. Furthermore, persistent rhinitis has been shown to be a distinct disease entity. Further efforts are required to disseminate and implement evidence-based diagnostic and treatment guidelines for AR in primary care practice
Is the Allergic Rhinitis and its Impact on Asthma classification useful in daily primary care practice?
Is the Allergic Rhinitis and its Impact on Asthma classification useful in daily primary care practice?
Repeated disinfectant use in broiler houses and pig nursery units does not affect disinfectant and antibiotic susceptibility in Escherichia coli field isolates
Background Disinfectants are frequently used in animal production to reduce or eliminate the load of infectious agents and parasites in buildings and equipment associated with the housing or transportation of animals. There are growing concerns that the use of disinfectants would select for resistance to antibiotics and disinfectants. The aim of this study was to determine the effect of repeated use of different disinfectants on the disinfectant and antibiotic susceptibility under practical conditions in a broiler and pig pilot farm. Therefore, the susceptibility of Escherichia coli (E. coli) to 14 antibiotics and 4 disinfectants was monitored over a one-year period. Results High (20-50%) to very high (> 50%) resistance levels for ampicillin, sulfamethoxazole, trimethoprim and tetracycline were observed in both animal production types. Disinfectant susceptibility did not change over time and did not depend on the used disinfection product. Compared to in-use concentrations of formaldehyde, benzalkoniumchloride and a peracetic acid - hydrogen peroxide formulation, all E. coli strains remained susceptible indicating that the use of disinfectants did not select for disinfectant resistance. Moreover, no association could be found between the use of disinfectants and antibiotic resistance. Conclusions These findings suggest that repeated use of disinfectants in agricultural environments does not select for antibiotic resistance nor does it reduce disinfectant susceptibility
Branch enclosure BVOC flux measurements from Fagus sylvatica L. in a natural forest environment: preliminary results
Applied research note : biomonitoring of mycotoxins in blood serum and feed to assess exposure of broiler chickens
Because European maximum guidance values of mycotoxins are only available for feed, mycotoxin exposure in animals is mainly monitored by feed analysis. However, proper sample collection is needed to ensure reliable results because of uneven distributions and disproportional spread of mycotoxins in feed which can hamper the evaluation of mycotoxin exposure in animals. A cross-sectional study was performed on 40 randomly selected broiler farms in Belgium. During a farm visit at the animal's age of 28 d, a pooled feed sample at the beginning and the end of the feed line was collected. Feed samples were analyzed by a validated multimycotoxin LC-MS/MS method. Moreover, serum samples were collected from 10 randomly selected chickens per farm. Serum concentrations of mycotoxins and major in vivo phase I metabolites were analyzed quantitatively, whereas the presence of phase II metabolites was determined in a qualitative approach by an UPLC-HRMS method. Deoxynivalenol (DON) was the most frequently occurring mycotoxin, being present in 74% of the feed samples, with an average concentration of 270 +/- 171 mu g/kg and a maximum concentration of 751 mu g/kg in positive samples. Also the acetylated forms 3and 15-acetyldeoxynivalenol (3 and 15ADON) were present in half of the samples, however, at lower concentrations (8 +/- 3 mu g 3ADON and 10 +/- 7 mu g 15ADON/kg). Only in 17.5% of the farms, DON was detected in serum samples at a mean serum concentration and standard deviation (SD) of 11 +/- 19 ng/mL. The maximum serum concentration of 49 ng DON/ mL was detected in broilers which were fed a diet that was contaminated with 191 mu g DON/kg, whereas the maximum concentration of DON in feed was 751 mu g/kg. Besides, 3 and 15ADON were only detected in 10% of the serum samples (max. 1.3 ng/mL). Sulfate conjugates of DON were only detected in a few serum samples. Qualitative screening for phase II metabolites of other mycotoxins showed similar results. Overall, correlations between feed and serum concentrations of all mycotoxins were lacking (R-2 = 0.18 for DON)
- …