A very rare mass in the uterus: Malignant lymphoma

The female genital area is the fi rst site of malignant lymphoma; is a very rare localization.While most genital lymphomas occur in the vagina or cervix, uterine corpus is very rare [1]. Patients usually present with bleeding or pelvic, low back pain, but very rarely tumors are discovered through a routine examination. In the present case; When the radiological examination was performed for avascular femoral necrosis, it was thought that myoma was the incidental mass. However, the patient had no preoperative diagnosis and the pathology was high grade B-cell lymphoma located in the uterus. We were unable to make a preoperative diagnosis and we thought that it could be lyomyosarcoma. Here we report a case of primary lymphoma of the uterus, which is very rare among postmenopausal masses.</p

The Effects of Preeclampsia Severity and Thrombocytopenia on the Prognosis of Hypertensive Pregnant Women

OBJECTIVE: The present study was aimed to determine the effects of preeclampsia severity and thrombocytopenia on maternal and fetal prognosis in hypertensive pregnant women, and to discuss the clinical and biochemical findings in light of the literature. STUDY DESIGN: Three hundred and one pregnant patients, who had been admitted to the Department of Obstetrics and Gynecology of our clinic, with the diagnosis of preeclampsia between October 2006 and October 2008, were retrospectively evaluated. The patients were divided into two groups as patients with mild and severe preeclampsia. Additionally, the patients were analyzed in two subgroups according to their platelet counts, as the groups with low and normal platelet counts. RESULTS: When the patients with mild and severe preeclampsia were compared with regard to maternal complications, no significant difference was determined between the two groups (p>0.05). However, a significant difference was noted between the groups with respect to the development of eclampsia and HELLP syndrome (p<0.05). Eclampsia (n=17; 12%) and HELLP syndrome (n=30; 21.1%) were more common in the patients with severe preeclampsia. On the other hand, no significant difference was noted between the two groups in terms of fetal outcomes (p>0.05). When the patients with low and the normal platelet counts were compared with respect to maternal complications, it was noted that HELLP syndrome (n=39; 51%) and eclampsia (n=11; 14.5%) were more common in patients with low platelet counts, when compared to the patients with normal platelet counts,and difference between the two groups was significant (p<0.05). Birth weight was significantly lower in patients with low platelet counts (p<0.05). CONCLUSIONS: There is a significant relationship between the severity of preeclampsia and potential complications. The risk for the development of HELLP syndrome and eclampsia increases in patients with severe preeclampsia. Furthermore, the risk for the development of complications increases with a decreased platelet count

Vaginal Preparation with Povidone Iodine and Postcesarean Infectious Morbidity: A Retrospective Trial

OBJECTIVE: The aim of the study was to evaluate the effect of preventing development of postpartum infections by vaginal preparation with povidone iodine before cesarean delivery, with a retrospective file scanning. STUDY DESIGN: This study included 250 pregnant women undergoing cesarean delivery, who applied our clinic between the dates 2010-2011. All women received the standard antibiotic prophylaxis, 1 gr cefazolin iv before 30 minutes from the operation. Patients were investigated in two groups, vaginal cleansing with povidone iodine before cesarean delivery (126 case) or no cleansing (124 case), the groups compared with presence of postoperative fever endometritis and wound infection. RESULTS: Demographic characteristics of two groups were similar. There were no differences in age, height, weight, BMI, time of pregnancy, number of prior cesarean delivery, preoperative-postoperative time of staying in hospital, preoperative - postoperative hemoglobin values (p>0.05); there was only statistically significant difference in operating time (p<0.05). Analyzing the distribution of postoperative fever, there was only one case in vaginal cleansing group and four cases in the other group. There was no statistically significant difference between the groups (p>0.05). Comparing the two groups with postoperative wound infection, there is only one case in vaginal cleansing group and three cases in the other group. There is no statistically significant difference between the groups (p>0.05). Because of absence of endometritis in two, groups, we could not assess efficiency of vaginal cleansing in postpartum endometritis. No statistically significant difference was determined between the groups, in postoperative fever and postoperative wound infection (p>0.05). CONCLUSIONS: Vaginal cleansing with povidone iodine before cesarean delivery may decrease postoperative fever and wound infection morbidities, although this is not statistically significant

The Importance of Serum Prolidase Activity in Endometriosis

Objective: In this study, our objective was to evaluate the abnormal collagen destruction and turnover and the prolidase activity in the etiopathogenesis of endometriosis, which may deteriorate the collagenous structure of exracellular matrix (ECM). Materials and Methods: For the assessment of the prolidase activity, venous blood samples were obtained from 37 patients, who had applied to the outpatient department of the Medical Faculty at Ondokuz Mayıs University with complaints of pelvic pain, dysmenorrhea and infertility between October 1st, 2011 and February 15th, 2012, underwent clinical and ultrasonographic examination, prediagnosed with endometriosis, and scheduled for laparoscopy or laparotomy. A total of 22 patients, who were diagnosed with endometriosis via intraoperative exploration and/or pathological examination, constituted the study group and the remaining 15 patients, who did not have any pathological finding or were diagnosed with a benign disease except for endometriosis, constituted the control group. Serum samples obtained from all patients were first centrifuged and then stored in a freezer at -70 C until the time of analysis. During the analysis, the prolidase activity was measured following the necessary biochemical enzymatic processing. Results: We found a statistically significant difference between stage 4 and stage 1,2,3 patients in the study group regarding the CA 125 levels (p=0.018). On the other hand, there was no statistically significant difference between stage 1,2,3 patients in the study group and the control group for serum prolidase levels (p=0.778). There was a statistically significant difference between stage 4 endometriosis patients in the study group and the control group considering the serum prolidase levels (p=0.026). Conclusion: We conclude that serum prolidase activity has a critical function in the development of the endometriotic lesions. In endometriosis patients, the increase in the serum prolidase activity may play an important role in the progress to more advanced stages and in the development of infertility

Multidisciplinary Management of Giant Fetal Sacrococcygeal Teratom

Sacrococcygeal Teratoma (SCT) is one of the most frequent tumors of the newborn period. SCT is seen in varying sizes, and there is a relationship between the size and the clinical course. Postoperative prognosis of SCT with a low malign potential is good in the newborn period. Prenatal follow-up and postnatal management are rather important. We described our patient who was diagnosed in the early weeks and followed up till week 37, and then was given birth by caesarean section. The hemodynamic findings were stabilized during the newborn period. the patient was successfully operated by pediatric surgeons to restore her health

Primary Pelvic Involvement of Hydatid Disease

Hydatid disease is caused by larval stage of a parasite named as Echinococcus. To diagnose this condition may be challenging without surgery and postoperative pathological examination due to limited value of serological studies but imaging techniques may give a clue when hydatid disease is suspected and hydatid disease shall be considered for differential diagnosis in pelvic mass. In the present case, we present a 75-year-old postmenopausal woman with pelvic hydatosis

Coexisting Endometrioid Type of Endometrial Carcinoma and Transitional Cell Carcinoma of Right Ovary Representing with Acute Abdominal Discomfort: A Case Report

Coexisting cancers involving both endometrium and ovary in the female genital tract is a well-recognized phenomenon. However, most of them are metastatic lesions arising from one organ and simultaneous primary cancer occurring in both organs is relatively rare. We report a case with dual primary cancer occurring in both ovaries and endometrium with two different histologies. Recently, a 53-year-old woman presented with abdominopelvic discomfort and had symptoms and signs of acute abdomen was found to have Grade III T1C, Nx Mx transitional cell carcinoma of the right ovary and Grade 1, T1a, Nx Mx endometrial carcinoma of endometrioid type. We present this case with a brief review of references

Retrospective Analysis of Placental Invasion Anomalies in a University Hospital

OBJECTIVE: Retrospective analysis of cases applying to the Gynecology and Obstetrics Clinic in Ondokuz Mayıs University Medicine School and diagnosed with placental invasion abnormalities, their common features and evaluation of test results STUDY DESIGN: Retrospective analyses and treatments were evaluated of cases applying to our clinic between February 2008 and February 2010 with placental invasion abnormalities and that diagnoses were ultrasonographically and pathologically finalized. RESULT: Four cases out of 6 were diagnosed preoperatively, and invasion of the bladder in one of these had been recognized preoperatively. All the cases had past cesarean section in their histories. Need for blood transfusion was less in cases diagnosed beforehand, and their hospitalization periods were shorter. Placenta previa was present in all the cases. Peripartum histerectomy was performed for all the six cases. Incidence of placental invasion abnormality was found as 1:294. This result may be cause of our university is a references origin in area. CONCLUSION: Maternal and fetal problems in cases of placenta invasion that are diagnosed previously and intervened after making the required preparations can be reduced