14 research outputs found
Effects of imperfect noise correlations on decoherence-free subsystems: SU(2) diffusion model
We present a model of an N-qubit channel where consecutive qubits experience
correlated random rotations. Our model is an extension to the standard
decoherence-free subsystems approach (DFS) which assumes that all the qubits
experience the same disturbance. The variation of rotations acting on
consecutive qubits is modeled as diffusion on the SU(2) group. The model may be
applied to spins traveling in a varying magnetic field, or to photons passing
through a fiber whose birefringence fluctuates over the time separation between
photons. We derive an explicit formula describing the action of the channel on
an arbitrary N-qubit state. For N=3 we investigate the effects of diffusion on
both classical and quantum capacity of the channel. We observe that
nonorthogonal states are necessary to achieve the optimal classical capacity.
Furthermore we find the threshold for the diffusion parameter above which
coherent information of the channel vanishes.Comment: 11 pages, 6 figures, improved clarity, more discussion, many new
references and the title change
Screening of Chloroquine, Hydroxychloroquine and Its Derivatives for Their Binding Affinity to Multiple SARS-CoV-2 Protein Drug Targets
Recently Chloroquine and its derivative Hydroxychloroquine have garnered enormous interest amongst the clinicians and health authorities’ world over as a potential treatment to contain COVID-19 pandemic. The present research aims at investigating the therapeutic potential of Chloroquine and its potent derivative Hydroxychloroquine against SARS-CoV-2 viral proteins. At the same time we have screened some chemically synthesized derivatives of Chloroquine and compared their binding efficacy with chemically synthesized Chloroquine derivatives through in silicoapproaches. For the purpose of the study, we have selected some essential viral proteins and enzymes implicated in SARS-CoV-2 replication and multiplication as putative drug targets.<br /