372 research outputs found

    Length and time scales of a liquid drop impact and penetration into a granular layer

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    Liquid drop impact and penetration into a granular layer are investigated with diverse liquids and granular materials. We use various size of SiC abrasives and glass beads as a target granular material. We also employ ethanol and glycerol aqueous solutions as well as distilled water to make a liquid drop. The liquid drop impacts the granular layer with a low speed (~ m/s). The drop deformation and penetration are captured by a high speed camera. From the video data, characteristic time scales are measured. Using a laser profilometry system, resultant crater morphology and its characteristic length scales are measured. Static strength of the granular layer is also measured by the slow pillar penetration experiment to quantify the cohesive force effect. We find that the time scales are almost independent of impact speed, but they depend on liquid drop viscosity. Particularly, the penetration time is proportional to the square root of the liquid drop viscosity. Contrastively, the crater radius is independent of the liquid drop viscosity. The crater radius is scaled by the same form as the previous paper, (Katsuragi, Phys. Rev. Lett. vol. 104, 2010, p. 218001)

    Notice of Prehistoric Implements Found in Siberia

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    Effect of an oral supplementation with a proprietary melon juice concentrate (Extramel®) on stress and fatigue in healthy people: a pilot, double-blind, placebo-controlled clinical trial

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    <p>Abstract</p> <p>Background</p> <p>Recent studies have demonstrated a correlation between perceived stress and oxidative stress. As SOD is the main enzyme of the enzymatic antioxidant defence system of the body, we evaluated the effect of an oral daily intake of a proprietary melon juice concentrate rich in SOD (EXTRAMEL<sup>®</sup>) on the signs and symptoms of stress and fatigue in healthy volunteers.</p> <p>Methods</p> <p>This randomized, double blind, placebo controlled clinical study was conducted with seventy healthy volunteers aged between 30 and 55 years, who feel daily stress and fatigue. They took the dietary supplement based on the melon juice concentrate (10 mg Extramel<sup>® </sup>corresponding to 140 IU SOD per capsule) or a placebo one time daily during 4 weeks. Stress and fatigue were measured using four observational psychometric scales: FARD, PSS-14, SF-12 and Epworth scale. The study was conducted by Isoclin, a clinical research organization, located in Poitiers, France.</p> <p>Results</p> <p>No adverse effect was noted. The supplementation with the proprietary melon juice concentrate bringing 140 IU SOD/day significantly improved signs and symptoms of stress and fatigue linked to performance, physical (pain, sleep troubles), cognitive (concentration, weariness, sleep troubles) or behavioural (attitude, irritability, difficulty of contact) compared to the placebo. In the same way, quality of life and perceived stress were significantly improved with SOD supplementation.</p> <p>Conclusion</p> <p>This pilot study showed that an oral supplementation with a proprietary melon juice concentrate rich in SOD may have a positive effect on several signs and symptoms of perceived stress and fatigue.</p

    Genetic and environmental determinants of children's food preferences

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    Omnivores have the advantage of a variety of food options but face a challenge in identifying foods that are safe to eat. Not surprisingly, therefore, children show a relative aversion to new foods (neophobia) and a relative preference for familiar, bland, sweet foods. While this may in the past have promoted survival, in the modem food environment it could have an adverse effect on dietary quality. This review examines the evidence for genetic and environmental factors underlying individual differences in children's food preferences and neophobia. Twin studies indicate that neophobia is a strongly heritable characteristic, while specific food preferences show some genetic influence and are also influenced by the family environment. The advantage of the malleability of human food preferences is that dislike of a food can be reduced or even reversed by a combination of modelling and taste exposure. The need for effective guidance for parents who may be seeking to improve the range or nutritional value of foods accepted by their children is highlighted

    Démarche incrémentale pour l'évaluation d'un modèle multi-agent en éthologie

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    National audienceCet article propose une démarche d'évaluation incrémentale pour évaluer un modèle censé rendre compte d'un phénomène biologique. Il présente dans un premier temps le phénomène collectif cible : à savoir le comportement de différenciation observés dans des groupes de rats, le modèle qui en a été fait puis son évaluation. Le fait d'envisager l'évaluation de manière incrémentale permet alors de voir jusqu'à quel point le modèle répond aux attentes et permet de mettre en évidence de nouvelles questions en éthologie qui seront abordées dans la dernière partie

    Neural basis of developing salt taste sensation: Response changes in fetal, postnatal, and adult sheep

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    To learn whether salt taste responses change during mammalian development, we recorded from multifiber preparations of the chorda tympani while stimulating the anterior tongue in sheep fetuses, lambs, and adults. Stimuli were 0.5 M NH4C1, KC1, NaCl, and LiCl, and 0.05–0.75 M concentration series of the first three salts. Ultrastructural studies were made of taste buds at different ages to determine whether morphological elements such as microvilli and tight junctions are present in young fetuses. Substantial changes occur in relative salt taste responses, throughout development. In fetuses that are beginning the last third of gestation, NaCl and LiCl elicit much smaller response magnitudes than NH4C1 and KC1. Throughout the rest of gestation and postnatally, the NaCl and LiCl responses gradually increase in magnitude relative to NH4C1 and KCL In adults, NaCl, LiCl, and NH4Cl all elicit similar response magnitudes and KC1 is less effective as a taste stimulus. At ages when response ratios for the 0.5 M salts are changing, there are no changes in shapes of the response/concentration functions for individual salts. Furthermore, microvilli are present on taste bud cell apices and tight junctions are found between cells in the youngest fetuses studied. Therefore, initial stimulus-receptor membrane contacts are probably similar to those in adults. Our data suggest that different membrane components interact with the various monochloride salts and that taste receptors contain different proportions of these various membrane components at different developmental stages. Therefore young taste bud cells do not have the same salt response characteristics as mature cells, and a changing neural substrate underlies development of salt taste function, both pre- and postnatally.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/50018/1/902150207_ftp.pd

    Preventing childhood obesity: what works?

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    Rates of overweight in North American children and adolescents have increased dramatically since the 1970s. Childhood obesity has reached epidemic proportions and calls for prevention and treatment programs to reverse this trend have been made. However, the evidence base needed for effective action is still incomplete, especially for childhood obesity prevention programs. This paper focuses on primary prevention of childhood obesity and has three aims: (1) to briefly describe current primary prevention approaches for childhood obesity and the evidence for their impact; (2) to elucidate promising, but untested intervention strategies using an ecological framework and evidence from experimental and epidemiological research on factors influencing children\u27s eating and weight status; and (3) to introduce a multiphase strategy for screening intervention components and building and evaluating potent interventions for childhood obesity. Most childhood obesity prevention programs have focused on school-aged children and have had little success. We suggest that, given these findings, prevention efforts should be expanded to explore other contexts in which children live as possible settings for intervention efforts, including the family and childcare settings. Given that 25% of preschool children are already overweight, intervening with children before school entry should be a priority. A review of experimental research on the developing controls of food intake in infancy and childhood suggests possible intervention strategies, focusing on parenting and aspects of the feeding environment. Epidemiological findings point to even earlier modifiable risk factors, including gestational weight gain, maternal prepregnancy weight, and formula feeding. However, the potential impact of altering these risk factors remains to be evaluated. In response to this problem, we suggest a new, multiphase method for accomplishing this, including screening intervention components, refining intervention designs and confirming component efficacy to build and evaluate potent, optimized interventions

    Blood pressure in blacks and whites and its relationship to dietary sodium and potassium intake

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    The 24-hour dietary intake and blood pressure of 1928 black and 9739 white adults derived from the data sets of the first US National Health and Nutrition Examination Survey (NHANES I) of 1971-1974 were analyzed. Contrary to expectation, the absolute and relative intakes of sodium and potassium in blacks were less than those of whites. However, because the difference in potassium was greater than the difference in sodium, blacks did have a significantly higher sodium/potassium ratio than whites. Blacks had significantly higher blood pressure than whites even when adjusted for differences in sodium/potassium ratio. It is concluded that the higher blood pressure and prevalence of hypertension in blacks does not appear to be a function of an absolutely greater dietary sodium intake, but related to a relatively low intake of potassium. It is possible that blacks have a greater sensitivity than whites to the hypertensinogenic effects of sodium which, coupled with the relatively low dietary intake of potassium, accounts for their increased blood pressure.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/25014/1/0000441.pd
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