10 research outputs found

    Bispectral Index In Calves Anesthetized With Xylazine, Midazolam, Ketamine, Isoflurane And Subjected To Continuous Rate Infusion Of Lidocaine

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    PURPOSE: To assess the bispectral index (BIS) and recovery in calves anesthetized with xylazine, midazolam, ketamine and isoflurane and subjected to CRI of lidocaine. METHODS: Xilazine was administered followed by ketamine and midazolam, orotracheal intubation and maintenance on isoflurane using mechanical ventilation. Lidocaine (2 mg kg-1 bolus) or saline (0.9%) was administered IV followed by a CRI (100 μg kg-1 minute-1) of lidocaine (L) or saline (C). Were recorded BIS, heart rate (HR), mean arterial pressure (MAP) and rectal temperature (RT) before administration of premedication (TB) and 15 minutes after (TX), before administering lidocaine (T0) and 20, 40, 60 and 80 minutes after the start of the CRI. Time do sternal recumbency (SRE) and standing (ST) and plasma lidocaine concentration also evaluated. RESULTS: In both treatments BIS decreased significantly at all times compared to TB. TX was higher than the subsequent times. HR decreased from baseline at all times and decreased from T40 in L compared to C. SRE was higher in L compared to C. CONCLUSIONS: Bispectral index values were consistent with the degree of hypnosis of the animals. Lidocaine did not potentiate isoflurane anesthesia assessed by BIS in unstimulated calves anesthetized with constant E´Iso. Lidocaine increased the time to sternal recumbency.3016772Haga, H.A., Dolvik, N.I., Evaluation of the bispectral index as an indicator of degree of central nervous system depression in isoflurane-anesthetizes horses (2002) Am J Vet Res, 63 (3), pp. 438-442Henao-Guerreno, P.N., McMurphy, R., Kukanich, B., Hodgson, D.S., Effect of morphine on the bispectral index during isoflurane anesthesia in dogs (2009) Vet Anaesth Analg, 36 (2), pp. 133-143Rosow, C., Manberg, P.J., Bispectral index monitoring (2001) Anesthesiol Clin North Am, 19 (4), pp. 947-966Antognini, J.F., Wang, X.W., Cartens, E., Isoflurane anaesthetic depth in goats monitored using the bispectral index of the electroencephalogram (2000) Vet Res Commun, 24 (6), pp. 361-370Martin-Cancho, M., Lima, J.R., Luis, L., Crisóstomo, V., Ezquerra, L.J., Carrasco, M.S., Usón-Gargallo, J., Bispectral index, spectral edge frequency 95%, and median frequency recorded for various concentration of isoflurane and sevoflurane in pigs (2003) Am J Vet Res, 64 (7), pp. 866-873March, P.A., Muir, W.W., Use of the bispectral index as a monitor of anesthetic depth in cats anesthetized with isoflurane (2003) Am J Vet Res, 64 (12), pp. 1534-1541Campagnol, D., Teixeira Neto, F.J., Monteiro, E.R., Beier, L.S., Aguiar, J.A., Use of bispectral index to monitor depth of anesthesia in isoflurane-anesthetized dogs (2007) Am J Vet Res, 68 (12), pp. 1300-1307Garcia-Pereira, F.L., Greene, A.S., Keegan, R.D., McEwen, M.M., Tibary, A., Effects of intravenous butorphanol on cardiopulmonary function in isoflurane-anesthetized alpacas (2007) Vet Anesth Analg, 34 (4), pp. 269-274Muir, W.W., Wiese, A.J., March, P.A., Effects of morphine, lidocaine, ketamine, and morphine-lidocaine-ketamine drug combination on minimum alveolar concentration in dogs anesthetized with isoflurane (2003) Am J Vet Res, 64 (9), pp. 1155-1160Vesal, N., Spadavecchia, C., Steiner, A., Kirscher, F., Levionnois, O.L., Evaluation of the isoflurane-sparing effects of lidocaine infusion during umbilical surgery in calves (2011) Vet Anaest Analg, 38 (5), pp. 451-460Dzikiti, T.B., Hellebrekers, P., Van Dijk, P., Effects of intravenous lidocaine on isoflurane concentration, physiological parameters, metabolic parameters and stress-related hormones in horses undergoing surgery (2003) J Vet Med A, 50 (4), pp. 190-195Pypendop, B.H., Ilkiw, J.E., The effects of intravenous lidocaine administration on the minimum alveolar concentration of isoflurane in cats. Anesth Analg (2005) Jan, 100 (1), pp. 97-101Doherty, T., Redua, M.A., Queiroz-Castro, P., Egger, C., Cox, S.K., Rohrbach, B.W., Effect of intravenous lidocaine and ketamine on the minimum alveolar concentration of isoflurane in goats (2007) Vet Anaest Analg, 34 (2), pp. 125-131Doherty, T.J., Frazier, D.L., Effect of intravenous lidocaine on halothane minimum alveolar concentration in ponies (1998) Equine Vet J, 30 (4), pp. 300-303Valverde, A., Doherty, T.J., Hérnandez, J., Davies, W., Effect of lidocaine on the minimum alveolar concentration of isoflurane in dogs (2004) Vet Anaest Analg, 31 (4), pp. 264-274. , OctMurrel, J.C., White, K.L., Johnson, C.B., Taylor, P.M., Doherty, T.J., Waterman-Pearson, A.E., Investigation of the EEG effects of intravenous lidocaine during halothane anaesthesia in ponies (2005) Vet Anaest Analg, 32 (4), pp. 212-221Robertson, S.A., Sanches, L.C., Merrit, A.M., Doherty, T.J., Effect of systemic lidocaine on visceral and somatic nociception in conscious horses (2005) Equine Vet J, 37 (2), pp. 122-127Moraes, A.N., Dyson, D.H., Mr, O., McDonell, W.N., Holmberg, D.L., Plasma concentration and cardiovascular influence of lidocaine infusions during isoflurane anesthesia in healthy dogs and dogs with subaortic stenosis (1998) Vet Surg, 27 (5), pp. 486-497Pypendop, B.H., Ilkiw, J.E., Assessment of the hemodynamic effects of lidocaine administered IV in isoflurane-anesthetized cats (2005) Am J Vet Res, 66 (4), pp. 661-668Ringer, S.K., Kalchofner, K., Boller, J., Fürst, A., Bettschart- Wolfensberger, R.A., clinical comparison of two anaesthetic protocols using lidocaine or medetomidine in horses. Vet. Anaesth (2007) Analg, 34 (4), pp. 257-268Valverde, A., Rickey, E., Sinclair, M., Rioja, E., Pedernera, J., Hathway, A., Cruz, A., Comparison of cardiovascular function and quality of recovery in isoflurane-anaesthetised horses administered a constant rate infusion of lidocaine or lidocaine and medetomidine during elective surgery (2010) Equine Vet. J, 42 (3), pp. 192-199Cantalapietra, A.G., Villanueva, B., Pereira, J.L., Anaesthetic potency of isoflurane in cattle: Determination of the minimum alveolar concentration (2000) Vet Anaesth Analg, 27 (1), pp. 22-26Mendes, F.D., Chen, L.S., Borges, A., Babadópulos, T., Ilha, J.O., Alkharfy, K.M., Mendes, G.D., De Nucci G. Ciprofibrate quantification in human plasma by high performance liquid chromatography coupled with electrospray tandem mass spectrometry for pharmacokinetic studies (2012) J Chromatogr B Analyt Technol Biomed Life Sci, 879 (24), pp. 2361-2368. , Aug;15Johansen, J.W., Sebel, P.S., Development and clinical application of electroencephalographic bispectrum monitoring (2000) Anesthesiology, 93 (5), pp. 1336-1344Kissin, I., Depth of anesthesia and bispectral index monitoring (2000) Anesth Analg, 90 (5), pp. 1114-1117March, P.A., Muir, W.W., Bispectral analysis of the electroencephalogram: A review of its development and use in anesthesia (2005) Vet Anaest Analg, 32 (5), pp. 241-255Hans, G.A., Lauwick, S.M., Kaba, A., Bonhomme, V., Struys, M.M., Hans, P.C., Lamy, M.L., Joris, J.L., Intravenous lidocaine infusion reduces bispectral index-guided requirements of propofol only during surgical stimulation (2010) Br J Anaesth, 105 (4), pp. 471-479Wilson, R.A., Soel, L.K., Beztarosti, K., Lamers, J.M., Verdouw, P.D., Negative inotropy of lidocaine: Possible biochemical mechanisms (1993) Eur Heart J, 14 (2), pp. 284-289Pankucsi, C., Varrô, A., Nánási, P.P., Three distinct components of the negative inotropic action of lidocaine in dog Purkinje fiber (1996) Gen Pharmacol, 27 (1), pp. 69-71Valverde, A., Gunkelt, C., Doherty, T.J., Giguère, S., Pollak, A.S., Effect of a constant rate infusion of lidocaine on the quality of recovery from sevoflurane or isoflurane general anaesthesia in horses (2005) Equine Vet J, 37 (6), pp. 559-564Feary, D.J., Mama, K.R., Wagner, E.A., Thomasy, S., Influence of general anesthesia on pharmacokinetics of intravenous lidocaine infusion in horses (2005) Am J Vet Res, 66 (4), pp. 574-580. , Ap

    Aquisição de imunidade passiva em cabritos alimentados com colostro de cabras com e sem mastite

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    O objetivo deste trabalho foi avaliar a transferência de imunidade passiva de cabras, que pariram com mastite, para seus respectivos cabritos. Os animais foram distribuídos em dois grupos, a saber: grupo 1 (GI), constituído por cabritos, filhos de cabras sem isolamento microbiológico em ambas as glândulas mamárias, e grupo 2 (GII), composto por cabritos, filhos de cabras com resultado positivo à lactocultura, em pelo menos uma das glândulas mamárias. Foram coletadas amostras de colostro e sangue à parição, bem como às 24 e às 48 horas após o parto/nascimento. O diagnóstico e o monitoramento da mastite nos animais foram realizados por meio do California Mastitis Test (CMT), contagem de células somáticas e isolamento microbiológico. A proteína total foi mensurada pelo método do biureto, e as concentrações de imunoglobulina A (IgA), imunoglobulina G (IgG), transferrina, albumina e haptoglobina por meio da eletrofoerese em gel de poliacrilamida contendo dodecil sulfato de sódio (SDS-PAGE). Os agentes mais isolados na cultura microbiológica foram os Staphylococcus coagulase negativa. Não houve diferença significativa (P<0,05) entre os valores médios de imunoglobulina G (IgG) nos cabritos provenientes de cabras com mastite quando comparados aos recém-nascidos oriundos de cabras livres de infecções intramamárias. Da mesma forma, a atividade de gamaglutamiltransferase (GGT) não mostrou diferença entre os grupos em todos os momentos avaliados. A ingestão de colostro decorrente de cabras com mastite não causou falha na transferência de imunidade passiva nos respectivos conceptos

    Primeiro registro de Amblyomma geayi (Acari: ixodidae) em preguiça (Bradypus variegatus) no estado do Acre, Amazônia Ocidental: relato de caso

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    RESUMO O Amblyomma geayi é um carrapato da família Ixodidae, encontrado principalmente em mamíferos e aves silvestres de regiões tropicais da América do Sul. Descreve-se a ocorrência de um carrapato ixodídeo da espécie A. geayi, encontrado em uma preguiça (Bradypus variegatus) proveniente do Parque Zoobotânico da Universidade Federal do Acre, Rio Branco, Acre, Amazônia Ocidental

    Influence of dexamethasone and surfactant in the vitality and lung function of preterm lambs born by cesarean section

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    ABSTRACT The aim of this study was to assess the vitality and lung function of preterm lambs. Twenty seven preterm lambs were divided in four groups. Group I (n=6) preterm lambs/ control; group II (n=9) lambs born to mothers that were treated with dexamethasone antepartum; group III (n=6) lambs treated with surfactant; and group IV (n=6) lambs treated with surfactant and born to mothers that were treated with dexamethasone antepartum. The APGAR score was performed after birth (T0) and 15 minutes later (T1/4) to assess vitality. The vital signs, blood gas analysis, spirometry and capnometry were assessed immediately after birth and continued until 48 hours. Chest radiographs were performed at T0, T24 and T48. Significant rectal temperature interactions occurred at T1 and T6 depending on the type of treatment used. All animals showed low pH values, which were associated with high pCO2 values and HCO3 -values that increased over time from immediately after birth to two days of age. Higher tidal volume values were observed at T1/4, T1 and T24 when the animals were not treated with surfactant. Capnometry showed significant interactions between treatments at T0. Premature animals showed low vitality and impaired pulmonary function
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