Seasonal activity of frog erythrocytes by data of electrophoretic mobility

The peculiarities of frog erythrocyte electrophoretic mobility, coupled to the seasonal course of temperatures, have been studied. At the periods of anabiosis and of burst of hemopoiesis, in the vascular bed there increases the portion of functionally young erythrocytes (up to 22%) with increased values of the cell membrane surface charge. Preparation to winter is accompanied by a rise of the number of circulating functionally worn down blood cells (up to 60%) with low values of the superficial charge and low mobility in electrical field. Use of the cell microelectrophoresis method of evaluation of seasonal activity of frog erythrocytes allows obtaining objective data about the cellular surface charge and its depending functional cell activity without submitting the erythrocytes to modifying action

Astrophysical science metrics for next-generation gravitational-wave detectors

The second generation of gravitational-wave (GW) detectors are being built and tuned all over the world. The detection of signals from binary black holes is beginning to fulfil the promise of GW astronomy. In this work, we examine several possible configurations for third-generation laser interferometers in existing km-scale facilities. We propose a set of astrophysically motivated metrics to evaluate detector performance. We measure the impact of detector design choices against these metrics, providing a quantitative cost-benefit analyses of the resulting scientific payoffs

Gravitational waves from Sco X-1: A comparison of search methods and prospects for detection with advanced detectors

The low-mass X-ray binary Scorpius X-1 (Sco X-1) is potentially the most luminous source of continuous gravitational-wave radiation for interferometers such as LIGO and Virgo. For low-mass X-ray binaries this radiation would be sustained by active accretion of matter from its binary companion. With the Advanced Detector Era fast approaching, work is underway to develop an array of robust tools for maximizing the science and detection potential of Sco X-1. We describe the plans and progress of a project designed to compare the numerous independent search algorithms currently available. We employ a mock-data challenge in which the search pipelines are tested for their relative proficiencies in parameter estimation, computational efficiency, robust- ness, and most importantly, search sensitivity. The mock-data challenge data contains an ensemble of 50 Scorpius X-1 (Sco X-1) type signals, simulated within a frequency band of 50-1500 Hz. Simulated detector noise was generated assuming the expected best strain sensitivity of Advanced LIGO and Advanced VIRGO ($4 \times 10^{-24}$ Hz$^{-1/2}$). A distribution of signal amplitudes was then chosen so as to allow a useful comparison of search methodologies. A factor of 2 in strain separates the quietest detected signal, at $6.8 \times 10^{-26}$ strain, from the torque-balance limit at a spin frequency of 300 Hz, although this limit could range from $1.2 \times 10^{-25}$ (25 Hz) to $2.2 \times 10^{-26}$ (750 Hz) depending on the unknown frequency of Sco X-1. With future improvements to the search algorithms and using advanced detector data, our expectations for probing below the theoretical torque-balance strain limit are optimistic.Comment: 33 pages, 11 figure

Einstein@Home all-sky search for continuous gravitational waves in LIGO O2 public data

We conduct an all-sky search for continuous gravitational waves in the LIGO O2 data from the Hanford and Livingston detectors. We search for nearly-monochromatic signals with frequency between 20.0 Hz and 585.15 Hz and spin-down between -2.6e-9 Hz/s and 2.6e-10 Hz/s. We deploy the search on the Einstein@Home volunteer-computing project and follow-up the waveforms associated with the most significant results with eight further search-stages, reaching the best sensitivity ever achieved by an all-sky survey up to 500 Hz. Six of the inspected waveforms pass all the stages but they are all associated with hardware-injections, which are fake signals simulated at the LIGO detector for validation purposes. We recover all these fake signals with consistent parameters. No other waveform survives, so we find no evidence of a continuous gravitational wave signal at the detectability level of our search. We constrain the h0 amplitude of continuous gravitational waves at the detector as a function of the signal frequency, in half-Hz bins. The most constraining upper limit at 163.0 Hz is h0 = 1.3e25, at the 90% confidence level. Our results exclude neutron stars rotating faster than 5 ms with equatorial ellipticities larger than 1e-7 closer than 100 pc. These are deformations that neutron star crusts could easily support, according to some models

A high precision, compact electromechanical ground rotation sensor

We present a mechanical rotation sensor consisting of a balance pivoting on a tungsten carbide knife edge. These sensors are important for precision seismic isolation systems, as employed in land-based gravitational wave interferometers and for the new field of rotational seismology. The position sensor used is an air-core linear variable differential transformer with a demonstrated noise floor of 1×10^(−11)m/√Hz. We describe the instrument construction and demonstrate low noise operation with a noise floor upper bound of 5.7×10^(−9)rad/√Hz at 10 mHz and 6.4×10^(−10)rad/√Hz at 0.1 Hz. The performance of the knife edge hinge is compatible with a behaviorur free of noise from dislocation self-organized criticality

Investigation of antiparkinsonian activity of new imidazole-4,5-dicarboxylic acid derivatives on the experimental model of catalepsy

To study the antiparkinsonian activity of new ligands of the glutamate NMDA receptor complex -1,2-substituted imidazole-4,5-dicarboxylic acids - on an experimental model of catalepsy caused by haloperidol intraabdominal injections in rat

Design and initial characterization of a compact, ultra high vacuum compatible, low frequency, tilt accelerometer

A compact tilt accelerometer with high sensitivity at low frequency was designed to provide low frequency corrections for the feedback signal of the Advanced Laser Interferometer Gravitational Wave Observatory active seismic attenuation system. It has been developed using a Tungsten Carbide ceramic knife-edge hinge designed to avoid the mechanical 1/f noise believed to be intrinsic in polycrystalline metallic flexures. Design and construction details are presented; prototype data acquisition and control limitations are discussed. The instrument's characterization reported here shows that the hinge is compatible with being metal-hysteresis-free, and therefore also free of the 1/f noise generated by the dislocation Self-Organized Criticality in the metal. A tiltmeter of this kind will be effective to separate the ground tilt component from the signal of horizontal low frequency seismometers, and to correct the ill effects of microseismic tilt in advanced seismic attenuation systems

First search for gravitational waves from the youngest known neutron star

We present a search for periodic gravitational waves from the neutron star in the supernova remnant Cassiopeia A. The search coherently analyzes data in a 12 day interval taken from the fifth science run of the Laser Interferometer Gravitational-Wave Observatory. It searches gravitational-wave frequencies from 100 to 300 Hz and covers a wide range of first and second frequency derivatives appropriate for the age of the remnant and for different spin-down mechanisms. No gravitational-wave signal was detected. Within the range of search frequencies, we set 95% confidence upper limits of (0.7–1.2) × 10^(−24) on the intrinsic gravitational-wave strain, (0.4–4) × 10^(−4) on the equatorial ellipticity of the neutron star, and 0.005–0.14 on the amplitude of r-mode oscillations of the neutron star. These direct upper limits beat indirect limits derived from energy conservation and enter the range of theoretical predictions involving crystalline exotic matter or runaway r-modes. This paper is also the first gravitational-wave search to present upper limits on the r-mode amplitude