47 research outputs found
A characterization of positive linear maps and criteria of entanglement for quantum states
Let and be (finite or infinite dimensional) complex Hilbert spaces. A
characterization of positive completely bounded normal linear maps from
into is given, which particularly gives a
characterization of positive elementary operators including all positive linear
maps between matrix algebras. This characterization is then applied give a
representation of quantum channels (operations) between infinite-dimensional
systems. A necessary and sufficient criterion of separability is give which
shows that a state on is separable if and only if
for all positive finite rank elementary operators
. Examples of NCP and indecomposable positive linear maps are given and
are used to recognize some entangled states that cannot be recognized by the
PPT criterion and the realignment criterion.Comment: 20 page
Mathematical models for immunology:current state of the art and future research directions
The advances in genetics and biochemistry that have taken place over the last 10 years led to significant advances in experimental and clinical immunology. In turn, this has led to the development of new mathematical models to investigate qualitatively and quantitatively various open questions in immunology. In this study we present a review of some research areas in mathematical immunology that evolved over the last 10 years. To this end, we take a step-by-step approach in discussing a range of models derived to study the dynamics of both the innate and immune responses at the molecular, cellular and tissue scales. To emphasise the use of mathematics in modelling in this area, we also review some of the mathematical tools used to investigate these models. Finally, we discuss some future trends in both experimental immunology and mathematical immunology for the upcoming years
Is America coming apart? Socioeconomic segregation in neighborhoods, schools, workplaces, and social networks, 1970–2020
As income inequality in the United States has reached an all-time high, commentators from across the political spectrum warn about the social implications of these economic changes. America, they fear, is “coming apart” as the gap between the rich and poor grows into a fault line. This paper provides a comprehensive review of empirical scholarship in sociology, education, demography, and economics in order to address the question: How have five decades of growing economic inequality shaped America's social landscape? We find that growing levels of income inequality have been accompanied by increasing socioeconomic segregation across (1) friendship networks and romantic partners, (2) residential neighborhoods, (3) K-12 and university education, and (4) workplaces and the labor market. The trends documented in this review give substance to commentators' concerns: compared to the 1970s, rich and poor Americans today are less likely to know one another and to share the same social spaces. The United States is a nation divided.Published versio
Injury-Initiated Clot Formation Under Flow: A Mathematical Model with Warfarin Treatment
The formation of a thrombus (commonly referred to as a blood clot) can potentially pose a severe health risk to an individual, particularly when a thrombus is large enough to impede blood flow. If an individual is considered to be at risk for forming a thrombus, he/she may be prophylactically treated with anticoagulant medication such as warfarin. When an individual is treated with warfarin, a blood test that measures clotting times must be performed. The test yields a number known as the International Normalized Ratio (INR). The INR test must be performed on an individual on a regular basis (e.g., monthly) to ensure that warfarin’s anticoagulation action is targeted appropriately. In this work, we explore the conditions under which an injury-induced thrombus may form in vivo even when the in vitro test shows the appropriate level of anticoagulation action by warfarin. We extend previous models to describe the in vitro clotting time test, as well as thrombus formation in vivo with warfarin treatments. We present numerical simulations that compare scenarios in which warfarin doses and flow rates are modified within biological ranges. Our results indicate that traditional INR measurements may not accurately reflect in vivo clotting times