Modeling of Laboratory Tests on Saint-Roch-de-l\u27Achigan Clay with S-CLAY1S Model

This technical note presents some results of numerical simulations performed to evaluate the influence of anisotropy and destructuration on the stress-strain response of Saint-Roch-de-l\u27Achigan clay. The oedometer and triaxial tests were simulated with the finite-element method using two different constitutive models to represent the soil: the S-CLAY1S model, which accounted for anisotropy and destructuration, and the isotropic modified Cam clay model (MCC), which was used for comparison. In contrast to the MCC model, the S-CLAY1S model was able to simulate the compression curve for the whole range of stresses with one parameter set and, hence, represented soil behavior in the triaxial test in a more realistic way than the MCC. The results of this study confirm that when using recommended procedures for the determination and calibration of the input parameters, the S-CLAY1S model represents well the overall behavior of Saint-Roch-de-l\u27Achigan clay in the specific cases analyzed

Additive Manufacturing of Multi-Scale Porous Soft Tissue Implants That Encourage Vascularization and Tissue Ingrowth

Medical devices, such as silicone-based prostheses designed for soft tissue implantation, often induce a suboptimal foreign-body response which results in a hardened avascular fibrotic capsule around the device, often leading to patient discomfort or implant failure. Here, it is proposed that additive manufacturing techniques can be used to deposit durable coatings with multiscale porosity on soft tissue implant surfaces to promote optimal tissue integration. Specifically, the “liquid rope coil effect”, is exploited via direct ink writing, to create a controlled macro open-pore architecture, including over highly curved surfaces, while adapting atomizing spray deposition of a silicone ink to create a microporous texture. The potential to tailor the degree of tissue integration and vascularization using these fabrication techniques is demonstrated through subdermal and submuscular implantation studies in rodent and porcine models respectively, illustrating the implant coating's potential applications in both traditional soft tissue prosthetics and active drug-eluting devices

Food for thought: The underutilized potential of tropical tree‐sourced foods for 21st century sustainable food systems

1. The global food system is causing large-scale environmental degradation and is a major contributor to climate change. Its low diversity and failure to produce enough fruits and vegetables is contributing to a global health crisis. 2. The extraordinary diversity of tropical tree species is increasingly recognized to be vital to planetary health and especially important for supporting climate change mitigation. However, they are poorly integrated into food systems. Tropical tree diversity offers the potential for sustainable production of many foods, providing livelihood benefits and multiple ecosystem services including improved human nutrition. 3. First, we present an overview of these environmental, nutritional and livelihood benefits and show that tree-sourced foods provide important contributions to critical fruit and micronutrient (vitamin A and C) intake in rural populations based on data from sites in seven countries. 4. Then, we discuss several risks and limitations that must be taken into account when scaling-up tropical tree-based food production, including the importance of production system diversity and risks associated with supply to the global markets. 5. We conclude by discussing several interventions addressing technical, financial, political and consumer behaviour barriers, with potential to increase the consumption and production of tropical tree-sourced foods, to catalyse a transition towards more sustainable global food systems.ISSN:2575-831