1,388 research outputs found
Identifying the Burdens and Opportunities for Tribes and Communities in Federal Facility Cleanup Activities: Environmental Remediation Technology Assessment Matrix For Tribal and Community Decision-Makers
The cleanup of this country's federal facilities can affect a wide range of tribal and community interests and concerns. The technologies now in use, or being proposed by the Department of Energy, Department of Defense and other federal agencies can affect tribal treaty protected fishing, hunting and other rights, affect air and water quality thereby requiring the tribe to bear the burden of increased environmental regulation. The International Institute for Indigenous Resource Management developed a tribal and community decision-maker's Environmental Remediation Technology Assessment Matrix that will permit tribes and communities to array technical information about environmental remediation technologies against a backdrop of tribal and community environmental, health and safety, cultural, religious, treaty and other concerns and interests. Ultimately, the matrix will allow tribes and communities to assess the impact of proposed technologies on the wide range of tribal and community interests and will promote more informed participation in federal facility cleanup activities
THE SCENARIOS APPROACH TO ATTENUATION-BASED REMEDIES FOR INORGANIC AND RADIONUCLIDE CONTAMINANTS
Guidance materials based on use of conceptual model scenarios were developed to assist evaluation and implementation of attenuation-based remedies for groundwater and vadose zones contaminated with inorganic and radionuclide contaminants. The Scenarios approach is intended to complement the comprehensive information provided in the US EPA's Technical Protocol for Monitored Natural Attenuation (MNA) of Inorganic Contaminants by providing additional information on site conceptual models and extending the evaluation to consideration of Enhanced Attenuation approaches. The conceptual models incorporate the notion of reactive facies, defined as units with hydrogeochemical properties that are different from surrounding units and that react with contaminants in distinct ways. The conceptual models also incorporate consideration of biogeochemical gradients, defined as boundaries between different geochemical conditions that have been induced by waste disposal or other natural phenomena. Gradients can change over time when geochemical conditions from one area migrate into another, potentially affecting contaminant mobility. A recognition of gradients allows the attenuation-affecting conditions of a site to be projected into the future. The Scenarios approach provides a stepwise process to identify an appropriate category of conceptual model and refine it for a specific site. Scenario materials provide links to pertinent sections in the EPA technical protocol and present information about contaminant mobility and important controlling mechanism for attenuation-based remedies based on the categories of conceptual models
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GROUNDWATER RADIOIODINE: PREVALENCE, BIOGEOCHEMISTRY, AND POTENTIAL REMEDIAL APPROACHES
Iodine-129 ({sup 129}I) has not received as much attention in basic and applied research as other contaminants associated with DOE plumes. These other contaminants, such as uranium, plutonium, strontium, and technetium are more widespread and exist at more DOE facilities. Yet, at the Hanford Site and the Savannah River Site {sup 129}I occurs in groundwater at concentrations significantly above the primary drinking water standard and there is no accepted method for treating it, other than pump-and-treat systems. With the potential arrival of a 'Nuclear Renaissance', new nuclear power facilities will be creating additional {sup 129}I waste at a rate of 1 Ci/gigawatts energy produced. If all 22 proposed nuclear power facilities in the U.S. get approved, they will produce more {sup 129}I waste in seven years than presently exists at the two facilities containing the largest {sup 129}I inventories, ({approx}146 Ci {sup 129}I at the Hanford Site and the Savannah River Site). Hence, there is an important need to fully understand {sup 129}I behavior in the environment to clean up existing plumes and to support the expected future expansion of nuclear power production. {sup 129}I is among the key risk drivers at all DOE nuclear disposal facilities where {sup 129}I is buried, because of its long half-life (16 million years), high toxicity (90% of the body's iodine accumulates in the thyroid), high inventory, and perceived high mobility in the subsurface environment. Another important reason that {sup 129}I is a key risk driver is that there is the uncertainty regarding its biogeochemical fate and transport in the environment. We typically can define {sup 129}I mass balance and flux at sites, but can not accurately predict its response to changes in the environment. This uncertainty is in part responsible for the low drinking water standard, 1 pCi/L {sup 129}I, and the low permissible inventory limits (Ci) at the Savannah River Site, Hanford Site, and the former Yucca Mountain disposal facilities. The objectives of this report are to: (1) compile the background information necessary to understand behavior of {sup 129}I in the environment, (2) discuss sustainable remediation approaches to {sup 129}I contaminated groundwater, and (3) identify areas of research that will facilitate remediation of {sup 129}I contaminated areas on DOE sites. Lines of scientific inquiry that would significantly advance the goals of basic and applied research programs for accelerating {sup 129}I environmental remediation and reducing uncertainty associated with disposal of {sup 129}I waste are: (1) Evaluation of amendments or other treatment systems that can sequester subsurface groundwater {sup 129}I. (2) Develop analytical techniques for measurement of total {sup 129}I that eliminate the necessity of collecting and shipping large samples of groundwater. (3) Develop and evaluate ways to manipulate areas with organic-rich soil, such as wetlands, to maximize {sup 129}I sorption, minimizing releases during anoxic conditions. (4) Develop analytical techniques that can identify the various {sup 129}I species in the subsurface aqueous and solid phases at ambient concentrations and under ambient conditions. (5) Identify the mechanisms and factors controlling iodine-natural organic matter interactions at appropriate environmental concentrations. (6) Understand the biological processes that transform iodine species throughout different compartments of subsurface waste sites and the role that these processes have on {sup 129}I flux
Increasing Doses of Intraoperative Hydromorphone Do Not Reduce Postoperative Pain
Introduction:
• Intermediate and long acting opioids are given intraoperatively to reduce pain during emergence from anesthesia.
• Recent evidence suggests that intraoperative opioids have inconsistent effects on nociception and pain in the immediate postoperative period.
• Multiple potent, short-acting opioids such as remifentanil, sufentanil and fentanyl have been shown to produce dose-related increases in pain scores and opioid consumption in the immediate postoperative recovery period.
• Intraoperative doses of longer acting opioids such as morphine and methadone6 have been shown to reduce pain scores and narcotic requirements in the immediate postoperative period.
• Hydromorphone is an intermediate duration narcotic which is commonly used intraoperatively but has not been studied for its potential to reduce pain in the immediate postoperative period
Around the tangent cone theorem
A cornerstone of the theory of cohomology jump loci is the Tangent Cone
theorem, which relates the behavior around the origin of the characteristic and
resonance varieties of a space. We revisit this theorem, in both the algebraic
setting provided by cdga models, and in the topological setting provided by
fundamental groups and cohomology rings. The general theory is illustrated with
several classes of examples from geometry and topology: smooth quasi-projective
varieties, complex hyperplane arrangements and their Milnor fibers,
configuration spaces, and elliptic arrangements.Comment: 39 pages; to appear in the proceedings of the Configurations Spaces
Conference (Cortona 2014), Springer INdAM serie
Chamber basis of the Orlik-Solomon algebra and Aomoto complex
We introduce a basis of the Orlik-Solomon algebra labeled by chambers, so
called chamber basis. We consider structure constants of the Orlik-Solomon
algebra with respect to the chamber basis and prove that these structure
constants recover D. Cohen's minimal complex from the Aomoto complex.Comment: 16 page
Identifying the Burdens and Opportunities for Tribes and Communities in Federal Facility Cleanup Activities: Environmental Remediation Technology Assessment Matrix For Tribal and Community Decision-Makers
The cleanup of this country’s federal facilities can affect a wide range of tribal and community interests and concerns. The technologies now in use, or being proposed by the Department of Energy, Department of Defense and other federal agencies can affect tribal treaty protected fishing, hunting and other rights, affect air and water quality thereby requiring the tribe to bear the burden of increased environmental regulation. The International Institute for Indigenous Resource Management developed a tribal and community decision-maker’s Environmental Remediation Technology Assessment Matrix that will permit tribes and communities to array technical information about environmental remediation technologies against a backdrop of tribal and community environmental, health and safety, cultural, religious, treaty and other concerns and interests. Ultimately, the matrix will allow tribes and communities to assess the impact of proposed technologies on the wide range of tribal and community interests and will promote more informed participation in federal facility cleanup activities.
This research was completed money allocated during Round 1 of the Citizens’ Monitoring and Technical Assessment Fund (MTA Fund). Clark University was named conservator of these works.
If you have any questions or concerns please contact us at [email protected]://commons.clarku.edu/iiirm/1000/thumbnail.jp
Cuts and flows of cell complexes
We study the vector spaces and integer lattices of cuts and flows associated
with an arbitrary finite CW complex, and their relationships to group
invariants including the critical group of a complex. Our results extend to
higher dimension the theory of cuts and flows in graphs, most notably the work
of Bacher, de la Harpe and Nagnibeda. We construct explicit bases for the cut
and flow spaces, interpret their coefficients topologically, and give
sufficient conditions for them to be integral bases of the cut and flow
lattices. Second, we determine the precise relationships between the
discriminant groups of the cut and flow lattices and the higher critical and
cocritical groups with error terms corresponding to torsion (co)homology. As an
application, we generalize a result of Kotani and Sunada to give bounds for the
complexity, girth, and connectivity of a complex in terms of Hermite's
constant.Comment: 30 pages. Final version, to appear in Journal of Algebraic
Combinatoric
Impact of Radiotherapy, Chemotherapy and Surgery in Multimodal Treatment of Locally Advanced Esophageal Cancer
Objectives: It was the aim of this study to assess our institutional experience with definitive chemoradiation (CRT) versus induction chemotherapy followed by CRT with or without surgery (C-CRT/S) in esophageal cancer. Methods: We retrospectively analyzed 129 institutional patients with locally advanced esophageal cancer who had been treated by either CRT in analogy to the RTOG 8501 trial (n = 78) or C-CRT/S (n = 51). Results: The median, 2-and 5-year overall survival (OS) of the entire collective was 17.6 months, 42 and 24%, respectively, without a significant difference between the CRT and C-CRT/S groups. In C-CRT/S patients, surgery statistically improved the locoregional control (LRC) rates (2-year LRC 73.6 vs. 21.2%; p = 0.003); however, this was translated only into a trend towards improved OS (p = 0.084). The impact of escalated radiation doses (>= 60.0 vs. <60.0 Gy) on LRC was detectable only in T1-3 N0-1 M0 patients of the CRT group (2-year LRC 77.8 vs. 42.3%; p = 0.036). Conclusion: Definitive CRT and a trimodality approach including surgery (C-CRT/S) had a comparable outcome in this unselected patient collective. Surgery and higher radiation doses improve LRC rates in subgroups of patients, respectively, but without effect on OS. Copyright (C) 2012 S. Karger AG, Base
Likelihood Geometry
We study the critical points of monomial functions over an algebraic subset
of the probability simplex. The number of critical points on the Zariski
closure is a topological invariant of that embedded projective variety, known
as its maximum likelihood degree. We present an introduction to this theory and
its statistical motivations. Many favorite objects from combinatorial algebraic
geometry are featured: toric varieties, A-discriminants, hyperplane
arrangements, Grassmannians, and determinantal varieties. Several new results
are included, especially on the likelihood correspondence and its bidegree.
These notes were written for the second author's lectures at the CIME-CIRM
summer course on Combinatorial Algebraic Geometry at Levico Terme in June 2013.Comment: 45 pages; minor changes and addition
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