Investigation Of Junior And Senior High School Students' Attitudes Towards Correcting Mistakes : A casse Study in Guilin

Students' attitudes towards correcting mathematics wrong questions affect the effect of mathematics learning to a certain extent. Focusing on students' attitudes towards correcting maths wrong questions, discovering the problem from the root cause can provide an important basis for correcting behavior. This research uses quantitative methods. the data were taken using a questionnaire. The sample of this study was 622 students in Guilin, China. The results of the questionnaire were processed using Microsoft Word and SPSS. the students filled out a questionnaire Attitudes towards Correcting Mathematics Wrong Questions Scale to investigate the attitudes of junior and senior high school students to correcting mathematics wrong questions from the three dimensions of cognition, behavior tendency and emotion. This research found 1) the overall level of Junior and senior high school students' attitudes towards correcting mathematics wrong questions is relatively high; 2) There are differences in the three dimensions, that is, cognitive level>emotional level>behavioral tendency; 3) there are significant differences in the attitude of correcting mathematics wrong questions in gender, whether or not they are student leaders, whether the head teacher is a math teacher, and grade; 4) And there is a significant correlation between each dimension and mathematics academic performance; 5) the attitude of correcting mathematics wrong questions significantly positively affects mathematics academic performance

N-(5-Ethylsulfanyl-1,3,4-thiadiazol-2-yl)-2-(4,5,6,7-tetrahydrothieno[3,2-c]pyri­din-5-yl)acetamide

In the title compound, C13H16N4OS3, a thienopyridine­derivative, the tetra­hydro­pyridine ring exhibits a half-chair conformation, and the folded conformation of the mol­ecule is defined by the N—C—C—N torsion angle of −78.85 (16)°. The crystal packing features inter­molecular C—H⋯N, N—H⋯N and C—H⋯O hydrogen bonds

1-[4-(3-{[5-(4-Chloro­phen­yl)furan-2-yl]methyl­idene­amino}-2,5-dioxoimidazol­idin-1-yl)but­yl]-4-methyl­piperazine-1,4-diium dichloride hemihydrate

The title compound, C23H30ClN5O3 2+·2Cl−·0.5H2O, was synthesized by N-alkyl­ation of 1-({[5-(4-chloro­phen­yl)-2-furan­yl]methyl­ene}amino)-2,4-imidazolidinedione with 1-bromo-4-chloro­butane, and N-methyl­piperazine. In the crystal, the cations, anions and water mol­ecules are linked by O—H⋯Cl and N—H⋯Cl hydrogen bonds

Analysis of the EGFR gene mutation in patients with nonsmall cell lung cancer in a Chinese population

Purpose: To investigate the epidermal growth factor receptor (EGFR) gene mutations and analyze their clinical significance in patients with non-small cell lung cancer (NSCLC) in Hubei province of China.Methods: A total of 138 paraffin embedded tissues were taken from patients with NSCLC who were treated at Hubei Hospital from January 2014 to June 2015. The tissue DNA was extracted and EGFR mutation was evaluated by polymerase chain reaction (PCR) sequencing analysis of exons 18, 19, 20, and 21.Results: The overall mutation rate of EGFR gene was 30.43 % (42/138) in 138 NSCLC patients. The mutation rates of EGFR gene at exon 18, 19, 20, 21 were 0 %（0/138), 13.8 %（19/138), 0.7 % (1/138) and 15.9 % (22/138), respectively. The mutation rate of EGFR gene was higher in female patients than that in males (62.2 % (28/45) vs 15.1 % (14/93), p < 0.01), and higher in non-smoking patients than in smoking ones (p < 0.05), but had no correlation with age in NSCLC patients (p > 0.05). EGFR mutation frequency in adenocarcinoma was higher than that in squamous cell carcinoma: 33.9 % (41/121) vs. 5.9 % (1/17, p < 0.05).Conclusion: EGFR mutations in NSCLC patients mainly exist in exons 19 and 21, and the mutation rate of exon 21 is higher than that of exon 19, which is more commonly found in female, adenocarcinoma and non-smoking patients.Keywords: Non-small cell lung cancer, Epidermal growth factor receptor (EGFR), Targeted therapy, Sequencin

1-(4,5,6,7-Tetra­hydro­thieno[3,2-c]pyridin-5-yl)-2-{4-[3-(trifluoro­meth­yl)phen­yl]piperazin-1-yl}ethanone

In the title mol­ecule, C20H22F3N3OS, the piperazine ring has a chair conformation, and the N—C(=O)—C—N torsion angle is −59.42 (14)°. In the crystal, weak C—H⋯O and C—H⋯π inter­actions link the mol­ecules into layers parallel to (101)