Household Assets, School Enrollment and Parental Aspirations for Children\u27s Education in Rural China: Does Gender Matter?

Using rural household data from the China Household Income Project (CHIP) 2002, this paper provides an analysis of different effects of household assets independent of family income on children’s school enrollment and parental aspirations for education, examining both outcomes by child’s gender. The study first compares the responsiveness of boys’ and girls’ enrollment to the improvement of household assets, measured as liquid assets and net worth, relative to family income. The multivariate regression analysis further detects the effects of household assets on both boys’ and girls’ school enrollment and parental aspirations for children’s future education by child’s gender. Statistical results show that, compared to family income, household assets matter more for girls’ schooling than for boys’. In addition, household net worth is significantly associated with parental aspirations for children’s education regardless of gender. This study, albeit exploratory, sheds light on child welfare and education policies in rural China

Asset-Based Policy in China: Applied Projects and Policy Progress

Since the Center for Social Development (CSD) at Washington University in St. Louis introduced the idea of asset building in China in 2004, asset-based projects and policy discussion have drawn great attention from the central government and mainstream media. CSD research and consultation have played a central role in these developments

Asset Poverty in Urban China: A Study Using the 2002 Chinese Household Income Project

Defining asset poverty as insufficiency of assets to satisfy household basic needs for a limited period of time, the study examines asset poverty rates in urban China using the 2002 survey data from the Chinese Household Income Project (CHIP). We find that asset poverty rates in urban China are lower than those of developed countries, in part due to Chinese households’ strong commitment to precautionary savings and the low poverty standards. However, the liquid asset poverty rate is five times that of the income poverty rate in urban China. Notably, the asset-poverty-gap ratio shows that most households in asset poverty have zero liquid assets or negative net worth. Given the increasingly common trend for lower-income individuals to experience transient poverty and income uncertainty, asset building ought to be an integral part of the anti-poverty agenda to protect the poor from economic hardship and provide them with opportunities for economic growth

Discovery of highly potent HDAC8 PROTACs with anti-tumor activity

Various diseases are deeply associated with aberrations in HDAC8 functions. These aberrations can be assigned to either structural functions or catalytic functions of HDAC8. Therefore, development of HDAC8 degradation inducers might be more promising than HDAC8 inhibitors. We employed the proteolysis targeting chimera (PROTAC) strategy to develop a selective and potent HDAC8 degradation inducer CT-4 with single-digit nanomolar DC50 values and over 95% Dmax in both triple-negative breast cancer MDA-MB-231 cells and T-cell leukemia cells. Notably, CT-4 demonstrated potent anti-migration activity and limited anti-proliferative activity in MDA-MB-231 cells. In contrast, CT-4 effectively induced apototic cell death in Jurkat cells, as assessed by a caspase 3/7 activity assay and flow cytometry. Our findings suggest that the development of HDAC8 degradation inducers holds great potential for the treatment of HDAC8-related diseases

Institutional determinants of construction safety management strategies of contractors in Hong Kong

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