180 research outputs found

    Measuring Urban Spatial Activity Structures: A Comparative Analysis

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    Abstract: Human activity recognition has been of interest in the field of urban planning. This paper established a general framework by which expected human activity intensity (HAI) measured by the built environment and factual HAI measured by the Baidu thermal chart were estimated and comparatively analyzed so as to identify abnormal human activities in Hanghzou, China. Three elements of the built environment (i.e., residential density, road connectivity, and land-use mixing degree) from multi-source data with high precision are selected to assess the expected HAI. Results indicate Hangzhou has evolved into a polycentric city with three urban clusters. In addition, a significant positive correlation exists between the two types of HAIs. However, there are areas with spatial mismatches, particularly in the “urban village” and new towns, suggesting human activities are not equally distributed all over the city. Research implications, limitations, and future research needs are discussed

    Exploring native and non-native English speaker teachers’ perceptions of English teacher qualities and their students’ responses

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    Due to globalization, English has gradually become a lingua franca, leading to a rising demand for proficient English teachers all over the globe. In China, more EFL teachers are being recruited, particularly at the tertiary level, with a greater preference for so-called “native English speaking teachers (NESTs)” over “non-native English-speaking teachers (NNESTs)” due to the impacts of native-speakerism. Research has shown NESTs, NNESTs, and students are often misaligned in terms of beliefs about language learning and teaching which affect teaching effectiveness as well as student achievement. Recognizing this issue, this study investigated NESTs’, NNESTs’, and Chinese English-major students’ perceptions of characteristics of effective EFL teachers at four mid-tier universities across China. Findings from semi-structured interviews with 16 students suggest that NNESTs and Chinese English-major students had similar views on language learning and teaching. Both groups valued prerequisite qualities such as having expert knowledge, language skills, teaching skills, and professionalism. NESTs, however, valued qualities such as caring, patience, flexibility, engagement, and awareness of students’ learning needs. These differences are likely the result of these two groups of teachers’ linguistic, cultural, and educational background differences. The highly uniform views of the two groups of teachers suggest that they tended to emphasize certain qualities while disregarding others. These findings suggest the need to raise teachers’ and students’ awareness of the benefits of different types of teacher qualities so that curriculum design and lesson planning can be implemented for better instructional alignment to ultimately improve teaching effectiveness

    The effect of delignification process with alkaline peroxide on lactic acid production from furfural residues

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    Furfural residues produced from the furfural industry were investigated as a substrate for lactic acid production by simultaneous saccharification and fermentation (SSF). Alkaline peroxide was used for delignification of furfural residues to improve the final lactic acid concentration. The residue was treated with 1.3% to 1.7% hydrogen peroxide at 80 °C for 1 h with a substrate concentration of 3.33%. SSF of furfural residues with different delignification degrees were carried out to evaluate the effect of delignification degree on lactic acid production. Using corn hydrolysates/ furfural residues as substrates, SSF with different media were carried out to investigate the effect of lignin on the interaction between enzymes and lactic acid bacteria. Lactic acid bacteria had a negative effect on cellulase, thus resulting in the reduction of enzyme activity. Lignin and nutrients slowed down the decreasing trend of enzyme activity. A higher delignification resulted in a slower fermentation rate and lower yield due to degradation products of lignin and the effect of lignin on the interaction between enzymes and lactic acid bacteria. For the purpose of lactic acid production, a moderate delignification (furfural residues with the lignin content of 14.8%) was optimum

    Non-monotonic compositional dependence of isothermal bulk modulus of the (Mg1–xMnx)Cr2O4 spinel solid solutions, and its origin and implication

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    AbstractThe compressibility of the spinel solid solutions, (Mg1−xMnx)Cr2O4 with x = 0.00 (0), 0.20 (0), 0.44 (2), 0.61 (2), 0.77 (2) and 1.00 (0), has been investigated by using a diamond-anvil cell coupled with synchrotron X-ray radiation up to ∼10 GPa (ambient T). The second-order Birch–Murnaghan equation of state was used to fit the PV data, yielding the following values for the isothermal bulk moduli (KT), 198.2 (36), 187.8 (87), 176.1 (32), 168.7 (52), 192.9 (61) and 199.2 (61) GPa, for the spinel solid solutions with x = 0.00 (0), 0.20 (0), 0.44 (2), 0.61 (2), 0.77 (2) and 1.00 (0), respectively (KT′ fixed as 4). The KT value of the MgCr2O4 spinel is in good agreement with existing experimental determinations and theoretical calculations. The correlation between the KT and x is not monotonic, with the KT values similar at both ends of the binary MgCr2O4MnCr2O4, but decreasing towards the middle. This non-monotonic correlation can be described by two equations, KT = −49.2 (11)x + 198.0 (4) (x ≤ ∼0.6) and KT = 92 (41)x + 115 (30) (x ≥ ∼0.6), and can be explained by the evolution of the average bond lengths of the tetrahedra and octahedra of the spinel solid solutions. Additionally, the relationship between the thermal expansion coefficient and composition is correspondingly reinterpreted, the continuous deformation of the oxygen array is demonstrated, and the evolution of the component polyhedra is discussed for this series of spinel solid solutions. Our results suggest that the correlation between the KT and composition of a solid solution series may be complicated, and great care should be paid while estimating the KT of some intermediate compositions from the KT of the end-members

    A systematic bibliometric analysis on the clinical practice of CGM in diabetes mellitus from 2012 to 2022

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    BackgroundContinuous glucose monitoring (CGM) has revolutionized diabetes management, but a comprehensive analysis of its clinical implementation is lacking. This study aims to explore CGM in diabetes practice over the past decade using bibliometric analysis. It will identify trends, research focal points, and provide a framework for future investigations.Materials and methodsThe Web of Science Core Collection (WOSCC) was utilized to acquire literature pertaining to the employment of continuous glucose monitoring (CGM) in diabetes that was published between the years 2012 and 2022, and to conduct a comprehensive analysis of the associated citation data. To achieve bibliometric visualization and analysis of the collated data, the bibliography package in the Rstudio(v.4.2.2), Citespace 6.2.R4, and VOS viewer were employed.ResultsA total of 3024 eligible publications were extracted from 91 countries, with the United States being the leading country in terms of the number of issued articles. Furthermore, the annual publication rate has shown a gradual increase during the past decade. Among the various journals in this field, DIABETES TECHNOLOGY & THERAPEUTICS was identified as the most highly cited one. Keyword clustering analysis of the extracted publications indicates that the research hotspots in the past decade have primarily focused on “continuous glucose monitoring”, “glycemic variability”, “type 1 diabetes”, “hypoglycemia”, and “glycemic control”. Moreover, the analysis of keyword emergence reveals that “Time In Range” and “Young Adult” represent the current research frontiers for the years 2012-2022.ConclusionThe concept of Time in Range (TIR) has garnered considerable attention as a significant area of inquiry and an emerging research trend in the clinical practice of Continuous Glucose Monitoring (CGM) for Diabetes Mellitus. Moreover, recent investigations have demonstrated a growing focus on young adults with type 1 diabetes as the research population of interest. In the foreseeable future, research endeavors will persist in the pursuit of improving glycemic management among young adults through the utilization of continuous glucose monitoring (CGM) technology, while also delving into the examination of the Time in Range metric via supplementary clinical investigations

    Ciliary parathyroid hormone signaling activates transforming growth factor-β to maintain intervertebral disc homeostasis during aging

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    © 2018 The Author(s). Degenerative disc disease (DDD) is associated with intervertebral disc degeneration of spinal instability. Here, we report that the cilia of nucleus pulposus (NP) cells mediate mechanotransduction to maintain anabolic activity in the discs. We found that mechanical stress promotes transport of parathyroid hormone 1 receptor (PTH1R) to the cilia and enhances parathyroid hormone (PTH) signaling in NP cells. PTH induces transcription of integrin αvβ6 to activate the transforming growth factor (TGF)-β-connective tissue growth factor (CCN2)-matrix proteins signaling cascade. Intermittent injection of PTH (iPTH) effectively attenuates disc degeneration of aged mice by direct signaling through NP cells, specifically improving intervertebral disc height and volume by increasing levels of TGF-β activity, CCN2, and aggrecan. PTH1R is expressed in both mouse and human NP cells. Importantly, knockout PTH1R or cilia in the NP cells results in significant disc degeneration and blunts the effect of PTH on attenuation of aged discs. Thus, mechanical stress-induced transport of PTH1R to the cilia enhances PTH signaling, which helps maintain intervertebral disc homeostasis, particularly during aging, indicating therapeutic potential of iPTH for DDD

    AdaTaskRec:An Adaptive Task Recommendation Framework in Spatial Crowdsourcing

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    Spatial crowdsourcing is one of the prime movers for the orchestration of location-based tasks, and task recommendation is a crucial means to help workers discover attractive tasks. While a number of existing studies have focused on modeling workers' geographical preferences in task recommendation, they ignore the phenomenon of workers' travel intention drifts across geographical areas, i.e., workers tend to have different intentions when they travel in different areas, which discounts the task recommendation quality of existing methods especially for workers that travel in unfamiliar out-of-Town areas. To address this problem, we propose an Adaptive Task Recommendation (AdaTaskRec) framework. Specifically, we first give a novel two-module worker preference learning architecture that can calculate workers' preferences for POIs (that tasks are associated with) in different areas adaptively based on workers' current locations. If we detect that a worker is in the hometown area, then we apply the hometown preference learning module, which hybrids different strategies to aggregate workers' travel intentions into their preferences while considering the transition and the sequence patterns among locations. Otherwise, we invoke the out-of-Town preference learning module, which is to capture workers' preferences by learning their travel intentions and transferring their hometown preferences into their out-of-Town ones. Additionally, to improve task recommendation effectiveness, we propose a dynamic top-k recommendation method that sets different k values dynamically according to the numbers of neighboring workers and tasks. We also give an extra-reward-based and a fair top-k recommendation method, which introduce the extra rewards for tasks based on their recommendation rounds and consider exposure-based fairness of tasks, respectively. Extensive experiments offer insight into the effectiveness of the proposed framework.</p

    Multifeature Detection of Microaneurysms Based on Improved SSA

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    The early diagnosis of retinopathy is crucial to the prevention and treatment of diabetic retinopathy. The low proportion of positive cases in the asymmetric microaneurysm detection problem causes preprocessing to treat microaneurysms as noise to be eliminated. To obtain a binary image containing microaneurysms, the object was segmented by a symmetry algorithm, which is a combination of the connected components and SSA methods. Next, a candidate microaneurysm set was extracted by multifeature clustering of binary images. Finally, the candidate microaneurysms were mapped to the Radon frequency domain to achieve microaneurysm detection. In order to verify the feasibility of the algorithm, a comparative experiment was conducted on the combination of the connected components and SSA methods. In addition, PSNR, FSIM, SSIM, fitness value, average CPU time and other indicators were used as evaluation standards. The results showed that the overall performance of the binary image obtained by the algorithm was the best. Last but not least, the accuracy of the detection method for microaneurysms in this paper reached up to 93.24%, which was better than that of several classic microaneurysm detection methods in the same period
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