Low-cost, highly efficient, and tunable ultrafast laser technology based on directly diode-pumped Cr:Colquiriites

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2010.This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Cataloged from student submitted PDF version of thesis.Includes bibliographical references (p. 335-352).This doctoral project aims to develop robust, ultra low-cost ($5,000-20,000), highly-efficient, and tunable femtosecond laser technology based on diode-pumped Cr:Colquiriite gain media (Cr:LiCAF, Cr3+:LiSAF and Cr:LiSGaF). By using inexpensive single-mode diodes ($150) as the pump source, we have obtained continuous-wave (cw) output powers >250-mW with slope efficiencies >50%. Record cw tuning ranges were demonstrated for Cr:LiSAF (775-1042 nm), Cr:LiSGaF (777-977 nm), and Cr:LiCAF (754-871 nm). For femtosecond pulse generation, semiconductor saturable absorber mirrors (SESAMs/SBRs) were developed, which were used to initiate and sustain mode-locking. Typical performance was ~25-100 fs pulses, with an optical spectrum in the 770-920 nm range, with ~1-2 nJ of pulse energies from ~100-MHz repetition rate cavities. Record electrical-to-optical conversion efficiencies of ~10% were demonstrated in the cw mode-locked regime. A mode-locked tuning range of 767-817 nm, with ~130-fs long pulses was obtained by using Cr:LiCAF as gain medium. With the Cr:LiSAF gain medium, using regular SESAMs/SBRs centered around 800 nm, 850 nm, and 910 nm, mode-locked tuning ranges of 803-831 nm, 828-873 nm, and 890-923 nm were demonstrated, respectively. By using a broadband oxidized SESAM/SBR, a record tuning range of 800-905 nm was demonstrated with ~150-fs long pulses. Using an extended cavity Cr:LiCAF laser, pulse energies >15-nJ with peak powers exceeding 100-kW were obtained. We performed the first cavity-dumping experiments with a Cr:Colquiriite laser and demonstrated pulse energies >100-nJ, and peak powers approaching MW level, at repetition rates up to 50-kHz. Cr:LiCAF gain media were also pumped by single-emitter multimode diodes, where we obtained >2-W output power in cw operation, and ~100-fs pulses with 390-mW of average power at a repetition rate of 140 MHz in cw mode-locked operation. As an example application area for this low cost technology, we performed multiphoton microcopy experiments with a single-mode diode-pumped Cr:LiCAF laser. We also performed attosecond-resolution timing jitter characterization experiments of the femtosecond Cr:LiSAF laser, and measured a record-low upper limit for the integrated timing jitter of the Cr:LiSAF laser (137-attoseconds in 10 kHz-10 MHz range).by Umit Demirbas.Ph.D

Ozone Therapy and Hyperbaric Oxygen Treatment in Lung Injury in Septic Rats

Various therapeutic protocols were used for the management of sepsis including hyperbaric oxygen (HBO) therapy. It has been shown that ozone therapy (OT) reduced inflammation in several entities and exhibits some similarity with HBO in regard to mechanisms of action. We designed a study to evaluate the efficacy of OT in an experimental rat model of sepsis to compare with HBO. Male Wistar rats were divided into sham, sepsis+cefepime, sepsis+cefepime+HBO, and sepsis+cefepime+OT groups. Sepsis was induced by an intraperitoneal injection of Escherichia coli; HBO was administered twice daily; OT was set as intraperitoneal injections once a day. The treatments were continued for 5 days after the induction of sepsis. At the end of experiment, the lung tissues and blood samples were harvested for biochemical and histological analysis. Myeloperoxidase activities and oxidative stress parameters, and serum proinflammatory cytokine levels, IL-1β and TNF-α, were found to be ameliorated by the adjuvant use of HBO and OT in the lung tissue when compared with the antibiotherapy only group. Histologic evaluation of the lung tissue samples confirmed the biochemical outcome. Our data presented that both HBO and OT reduced inflammation and injury in the septic rats' lungs; a greater benefit was obtained for OT. The current study demonstrated that the administration of OT as well as HBO as adjuvant therapy may support antibiotherapy in protecting the lung against septic injury. HBO and OT reduced tissue oxidative stress, regulated the systemic inflammatory response, and abated cellular infiltration to the lung demonstrated by findings of MPO activity and histopathologic examination. These findings indicated that OT tended to be more effective than HBO, in particular regarding serum IL-1β, lung GSH-Px and histologic outcome

Widely unable dual-wavelength operation of Tm:YLF, Tm:LuAG, and Tm:YAG lasers using off-surface optic axis birefringent filters

BEYATLI, Ersen/0000-0002-2548-6858; Demirbas, Umit/0000-0001-8420-8965WOS: 000441287300009PubMed: 30129612In this work, we have demonstrated dual-wavelength continuous-wave laser operation in diode-end-pumped Tm:YLF, Tm:LuAG, and Tm:YAG lasers. A 3-mm-thick quartz birefringent filter with an optical axis 45 degrees to the surface plane was exploited for achieving broadly tunable two-color laser operation. By using the different orders of the filter with varying filter width and free spectral range values, dual-wavelength operation has been achieved in 11, 12, and 8 different wavelength pairs in Tm:YLF, Tm:LuAG, and Tm:YAG, respectively. Fine tuning of the rotation angle of the birefringent filter enabled control of laser power in each line. To our knowledge, this is the first report of multicolor laser operation in these gain media, and the technique used is applicable to other laser operation regimes including mode-locking. (C) 2018 Optical Society of AmericaTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [115F053]Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) (115F053)

Alexandrite: an attractive thin-disk laser material alternative to Yb:YAG?

Yb:YAG thin-disk (TD) technology has enabled construction of laser/amplifier systems with unprecedented average/peak power levels, and has become the workhorse of many scientific investigations. On the other hand, for some applications, the narrow emission bandwidth of Yb:YAG limits its potential, and the search for alternative broadband TD gain media with suitable thermo-optomechanical parameters is ongoing. The alexandrite gain medium has a broad emission spectrum centered around 750 nm, possesses thermomechanical strength that even outperforms Yb:YAG, and has unique spectroscopic properties enabling efficient laser operation even at elevated temperatures. In this work, we have numerically investigated the power scaling potential of continuous-wave (cw) alexandrite lasers in TD geometry for the first time. Using a detailed laser model, we have compared the potential cw laser performance of Yb:YAG, Ti:Sapphire, Cr:LiSAF, Cr:LiCAF, and alexandrite thin-disk lasers under similar conditions and show that among the investigated transition metal-doped gain media, alexandrite is the best alternative to Yb:YAG in power scaling studies at room temperature. Our analysis further demonstrates that potentially Ti:Sapphire is also a good alternative TD material, but only at cryogenic temperatures. However, in comparison with Yb:YAG, the achievable laser gain is relatively low for both alexandrite and Ti:Sapphire, which then requires usage of low-loss cavities with small output coupling for efficient cw operation

Passively Q-switched Cr:LiCAF laser with a saturable Bragg reflector

We present a low-cost multimode diode pumped passively Q-switched Cr:LiCAF laser operating near 800 nm. AlGaAs-based saturable Bragg reflectors (SBRs) were used for passive Q-switching. The system is experimentally characterized in detail using four different output couplers and two SBRs with different modulation depths. Pulse widths in the 1.5–4 µs range at repetition rates between 18 and 40 kHz were achieved with average powers up to 125 mW. The experimentally obtained results are compared with basic Q-switching theory and further performance improvement in terms of pulse length shortening and peak power scaling is elaborated

Temperature dependence of Alexandrite effective emission cross section and small signal gain over the 25-450 °C range

We present detailed measurements of effective emission cross section spectra of theAlexandrite gain medium in the 25-450 °C temperature range and provide analytic formulasthat can be used to match the measured spectra. The measurement results have been used toinvestigate the wavelength and temperature dependence of small signal gain, as well as gainbandwidth relevant for ultrafast pulse generation/amplification. We show that the estimated laserperformance based on the measured spectroscopic data provides a good fit to the results in theliterature. We further discuss the need for a detailed measurement of excited-state absorptioncross section in future studies