Relationship Between Pica and Laboratory Values in Patients with Iron Deficiency

INTRODUCTION: Pica is one of the symptoms of iron deficiency and a pathology that exacerbates the condition. In this study, we sought to identify the biomarkers associated with pica in iron-deficient patients. METHODS: The study included female iron deficient clinic applicants from April 2021 to August 2022. The main iron deficit inclusion criterion was ferritin <30 ug/L. Patients' demographics, hemograms, iron parameters, c-reactive protein levels, and presence and types of pica were recorded. Independent sample tests and logistic regression tests were used to analyze the data. RESULTS: There were a total of 381 patients who met the study's eligibility requirements (mean age 38.67+10.10). Fifty-three (13.9%) patients described pica. One hundred four of 381 patients (27.3%) showed non-anemic iron deficiency, while 277 (72.7%) had anemia. Pica was found in 9 (8.7%) non-anemic iron deficient individuals and 44 (15.9%) iron deficiency anemia patients. Pica subtypes geophagia (39.6%) and pagophagia (28.2%) were most common. Among the laboratory values, unsaturated iron binding capacity (UIBC), total iron binding capacity (TIBC) and transferrin saturation differed significantly between groups with and without pica (p=0.029, p=0.045 and, p=0.030, respectively). UIBC and TIBC were significant again with univariate logistic regression. DISCUSSION AND CONCLUSION: Elevated UIBC and TIBC values and decreased transferrin saturation appear to be associated with pica in iron-deficient patients

Unocculuded object grasping by using visual data

Automatic grasping objects can become important in the areas such as industrial processes, processes which are dangerous for human, or the operations which should be executed in the places, small for people work. In this study, it is aimed to design a robotic system for grasping unocculuded certain objects by using visual data. For this aim an experimental process was implemented. Visual data process can be divided in two main parts: identification and three dimensional positioning. Identification issue suffers from several conditions as rotation, camera position, and location of the subject in the frame. Also obtaining the features invariant from these conditions is important. Therefore Zernike moment method can be used to overcome these negativities. In order to identify the objects an artificial neural network was used to classify the objects by using Zernike moment coefficients. In the experimental system a parallel axis stereovision subsystem, a DSPFPGA embedded media processor, and five-axis robot arm were used. The success rate of artificial neural network was 98%. After identifying the objects, a sequential algebra were performed in the DSP part of the media processor and the position of the object according to robot arm reference point was extracted. After all, desired object in the instant frame was grasped and placed in different location by the robot arm

Unified resource allocation and mobility management technique using particle swarm optimization for VLC networks

In this paper, we present a unified resource allocation and mobility management algorithm based on particle swarm optimization (PSO) for indoor visible light communication (VLC) networks. We consider a VLC network where multiple LEDs serve as access points (APs). A centralized controller collects channel state information, quality of service requirements of the users, and the overload status of the APs. Based on the available information, in each time interval, the controller decides which user is served by which AP and assigns subcarriers to the users with the objective of maximizing both the system throughput and user satisfaction. We formulate the resource allocation problem as a constrained nonlinear integer programming problem and solve it using meta-heuristic PSO. Through an extensive simulation study, the superiority of the proposed algorithm in terms of system throughput and user satisfaction over round robin, best channel quality information, and genetic algorithms is demonstrated.Council for Scientific and Industrial ResearchPublisher versio

Knowledge levels and associated factors about newborn care of pregnants following by hospital

AMAÇ: Bu araştırmada bir hastanenin obstetrik polikliniğinde takip edilen gebelerin yenidoğan bakımı konusundaki bilgi düzeylerinin ve etkileyen faktörlerin belirlenmesi amaçlanmıştı. GEREÇ VE YÖNTEMLER: Tanımlayıcı tipteki bu araştırma bir hastanenin Obstetrik Polikliniği’nde takipli ve araştırmaya katılmayı kabul eden 118 gebe ile yürütüldü. Araştırmanın verileri 23 soru ve iki bölümden oluşan anket formunun yüzyüze gözlem altında uygulanması yoluyla toplandı. Verilerin istatistik analizlerinde tanımlayıcı istatistikler, ki-kare ve Fisher’in kesin testi kullanıldı ve p<0.05 istatistiksel anlamlılık düzeyi olarak kabul edildi. BULGULAR: Katılımcıların %40,7’si üniversite mezunu iken, %54,2’si çalışmakta idi. Sadece %13,6’sı bebek bakımı ile ilgili eğitim almıştı. Katılımcıların %84,7’si kundaklama, %72,9’u anne sütü verme zamanı, %71,2’si gün içinde emzirilme sayısı ve %66,1’i de yenidoğana yapılacak aşılar konularında doğru bilgi sahibi idi. Yenidoğanın bakımı ile ilgili konularla eğitim düzeyi, çalışma durumu ve bebek bakımıyla ilgili eğitim alma durumu arasında anlamlı farklılık bulundu (p<0.005). SONUÇ: Araştırmamızda katılımcıların yenidoğan bakımıyla ilgili bilgi düzeyleri yüksek bulunmuştur. Eğitim düzeyi yüksek, çalışan ve bebek bakımı eğitimi almış olanların daha bilgili olmaları, ülkemizde bu konuda eğitim verilmesinin ve kadının statüsünün arttırılmasının önemini göstermektedir.OBJECTIVE: The purpose of this study was to determined knowledge levels and associated factors about newborn care of pregnants following by obstetrics policlinic of a hospital. MATERIALS AND METHODS: This descriptive study was performed with 118 voluntary pregnants following by Obstetric Policlinic of a hospital. Study data was collected by a two part questionnaire which had 23 questions by using face to face interview. The data was evaluated by descriptive statatistics, chi square and Fisher exact tests. and p<0.05 has been accepted significany level. RESULTS: Of 40.7% participants were graduated from university and 54.2% of them employed. Only 13.6% of them had an education about newborn care. 84.7% of them had correct knowledge about swaddling, 72.9% of them had correct knowledge about breastfeeding time, 71.2% of them had correct knowledge about frequency of breastfeeding in a day and 66.1% of them had correct knowledge about vaccination of the newborn. There were significant differences between newborn care knowledge and education level, employment and having an education about newborn care (p<0.005). CONCLUSION: We find newborn knowledge levels of the participants high. Participants who are high educated, employed and have an education about newborn care have more knowledge about this subject. This results show us the importance of giving education about this subject and raising status of women in our country

Unified resource allocation and mobility management technique using particle swarm optimization for VLC networks

In this paper, we present a unified resource allocation and mobility management algorithm based on particle swarm optimization (PSO) for indoor visible light communication (VLC) networks. We consider a VLC network where multiple LEDs serve as access points (APs). A centralized controller collects channel state information, quality of service requirements of the users, and the overload status of the APs. Based on the available information, in each time interval, the controller decides which user is served by which AP and assigns subcarriers to the users with the objective of maximizing both the system throughput and user satisfaction. We formulate the resource allocation problem as a constrained nonlinear integer programming problem and solve it using meta-heuristic PSO. Through an extensive simulation study, the superiority of the proposed algorithm in terms of system throughput and user satisfaction over round robin, best channel quality information, and genetic algorithms is demonstrated.Council for Scientific and Industrial ResearchPublisher versio

Improvement in Attention and Executive Functions During Isotretinoin Treatment in Patients With Acne

Background and Design: We assessed attention, memory, verbal-linguistic ability, and executive functions in acne vulgaris patients before and during isotretinoin treatment.Materials and Methods: Fifty-two treatment-naive acne patients at baseline and 24 at the second visit were evaluated. A neurocognitive battery including the Rey Auditory Verbal Learning and Memory Test, Auditory Consonant Trigram Test, Controlled Word Association Test, Digit Span Test, Trail Making Test A and B and the Stroop Test was used. The Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I), Hospital Anxiety and Depression Scale (HADS), and the Liebowitz Social Anxiety Scale (LSAS) were also applied.Results: We found improvements in attention and executive functions at the second visit in comparison with the baseline evaluations. No alteration was found in verbal episodic memory, learning, working memory, and phonemic verbal fluency (Digit Span Forwards Test p=0.003, Trial Making-A Test p=0.002, Trial Making –B Test p=0.000, Stroop test p=0.028).Discussion: The positive effects of isotretinoin on cognitive functions may be related to the decline in acne lesions and less mental occupation with the social impacts of acne

The Effect of Corrected Inflammation, Oxidative Stress and Endothelial Dysfunction on Fmd Levels in Patients with Selected Chronic Diseases: A Quasi-Experimental Study.

While the pathophysiology of chronic disorders varies there are three basic mechanisms - inflammation, oxidative stress and endothelial dysfunction - that are common in many chronic diseases. However, the failure of these mechanisms to work synchronously can lead to morbidity complicating the course of many chronic diseases. We analyzed data of 178 patients from cohorts with selected chronic diseases in this quasi-experimental study. Endothelial dysfunction was determined by flow-mediated dilatation (FMD) and asymmetric dimethylarginine (ADMA) levels. Serum ADMA, high sensitive C-reactive protein (hs-CRP), serum PTX3, malondialdehyde (MDA), Cu/Zn-superoxide dismutase (Cu/Zn-SOD), glutathione peroxidase (GSH-Px) levels and FMD were studied in baseline and after 12 weeks of Morinda citrifolia (anti-atherosclerotic liquid- AAL), omega-3 (anti-inflammatory capsules- AIC) and extract with Alaskan blueberry (anti-oxidant liquid- AOL). Stepwise multivariate regression analysis was used to evaluate the association of FMD with clinical and serologic parameters. Serum ADMA, MDA, PTX3, hsCRP and albumin levels, and proteinuria were significantly decreased while CuZn-SOD, GSH-Px and FMD levels were significantly increased following AAL, AIC and AOL therapies. The FMD was negatively correlated with serum ADMA, MDA, PTX3, and hsCRP levels and positively correlated with CuZn-SOD and eGFR levels. ADMA and PTX3 levels were independently related to FMD both before and after AAL, AIC and AOL therapies. Our study shows that serum ADMA, MDA, PTX3 levels are associated with endothelial dysfunction in patients with selected chronic diseases. In addition, short-term AAL, AIC and AOL therapies significantly improves a number of parameters in our cohort and can normalize ADMA, PTX3, hsCRP and MDA levels

FRI0547 The Effect of Corrected Inflammation, Oxidative Stress and Endothelial Dysfunction on Fmd Levels in Patients with Selected Chronic Diseases: A Quasi-Experimental Study.

While the pathophysiology of chronic disorders varies there are three basic mechanisms - inflammation, oxidative stress and endothelial dysfunction - that are common in many chronic diseases. However, the failure of these mechanisms to work synchronously can lead to morbidity complicating the course of many chronic diseases. We analyzed data of 178 patients from cohorts with selected chronic diseases in this quasi-experimental study. Endothelial dysfunction was determined by flow-mediated dilatation (FMD) and asymmetric dimethylarginine (ADMA) levels. Serum ADMA, high sensitive C-reactive protein (hs-CRP), serum PTX3, malondialdehyde (MDA), Cu/Zn-superoxide dismutase (Cu/Zn-SOD), glutathione peroxidase (GSH-Px) levels and FMD were studied in baseline and after 12 weeks of Morinda citrifolia (anti-atherosclerotic liquid- AAL), omega-3 (anti-inflammatory capsules- AIC) and extract with Alaskan blueberry (anti-oxidant liquid- AOL). Stepwise multivariate regression analysis was used to evaluate the association of FMD with clinical and serologic parameters. Serum ADMA, MDA, PTX3, hsCRP and albumin levels, and proteinuria were significantly decreased while CuZn-SOD, GSH-Px and FMD levels were significantly increased following AAL, AIC and AOL therapies. The FMD was negatively correlated with serum ADMA, MDA, PTX3, and hsCRP levels and positively correlated with CuZn-SOD and eGFR levels. ADMA and PTX3 levels were independently related to FMD both before and after AAL, AIC and AOL therapies. Our study shows that serum ADMA, MDA, PTX3 levels are associated with endothelial dysfunction in patients with selected chronic diseases. In addition, short-term AAL, AIC and AOL therapies significantly improves a number of parameters in our cohort and can normalize ADMA, PTX3, hsCRP and MDA levels

Um Stent Mal Colocado na Artéria Septal Perfurante: Fístula Ventricular Direita, Hematoma do Septo Interventricular e Obstrução da Via de Saída do Ventrículo Direito

Resumo As fístulas coronário-camerais, embora consideradas em sua maioria como entidades congênitas, também têm sido encontradas como complicações de grandes traumas e intervenções coronárias percutâneas (ICPs).1 Por outro lado, o hematoma do septo interventricular (SIV) pode potencialmente surgir principalmente durante intervenções de oclusão total crônica retrógrada (OTC) e tem um curso benigno nesse contexto.2 Aqui, descrevemos uma complicação desafiadora da ICP (e sua estratégia de manejo) apresentando hematoma do SIV, fístula ventricular direita e obstrução da via de saída do ventrículo direito (VSVD) devido a um stent coronário mal implantado na artéria septal perfurante (ASP)