Cluster Model for Near-barrier Fusion Induced by Weakly Bound and Halo Nuclei

The influence on the fusion process of coupling transfer/breakup channels is investigated for the medium weight $^{6,7}$Li+$^{59}$Co systems in the vicinity of the Coulomb barrier. Coupling effects are discussed within a comparison of predictions of the Continuum Discretized Coupled-Channels model. Applications to $^{6}$He+$^{59}$Co induced by the borromean halo nucleus $^{6}$He are also proposed.Comment: 5 pages, 3 figures, FINUSTAR2 Conference, Aghios Nikolaus, Crete, Greece. 10-14 September 200

Visualising transformative spaces for education: a focus on lecture halls, computer rooms and studios

One room, three learning spaces for creative education. This image-led investigation shows how a standard blank room can be effectively transformed into three different kinds of learning environments: a lecture hall, a computer room and a studio. Research has shown that effective design of teaching spaces is beneficial to the learning experience and contributes to creating a more engaging relationship between teachers and learners. On the other hand, few visual resources have been produced to support this in the UK. This article seeks to fill this gap. The design of these classrooms applies Basye’s idea of campfire to stimulate and support interaction between teachers and learners. In particular, these visuals show how technology can improve the students’ experience of the lecture hall, provide adequate lighting, personal space and drawing devices in the computer room, and finally how gathering in a circle may replicate the benefits of campfires in the studio

Atomistic Characterization of Stochastic Cavitation of a Binary Metallic Liquid under Negative Pressure

We demonstrate the stochastic nature of cavitation in a binary metallic liquid Cu_(46)Zr_(54) during hydrostatic expansion by employing molecular dynamics (MD) simulations using a quantum mechanics (QM)-derived potential. The activation volume is obtained from MD simulations and transition-state theory. Extrapolation of the pressure dependence of the activation volume from our MD simulations to low tensile pressure agrees remarkably with macroscale cavitation experiments. We find that classical nucleation theory can predict the cavitation rate if we incorporate the Tolman length derived from the MD simulations

Molecular beacon-based real-time PCR detection of primary isolates of Salmonella Typhimurium and Salmonella Enteritidis in environmental and clinical samples

RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display the work; make derivative works; or make commercial use of the work - under the following conditions: the original author must be given credit; for any reuse or distribution, it must be made clear to others what the license terms of this work are.Abstract Background A fast and simple two-step multiplex real-time PCR assay has been developed to replace the traditional, laborious Salmonella serotyping procedure. Molecular beacons were incorporated into the assay as probes for target DNA. Target sequences were regions of the invA, prot6E and fliC genes specific for Salmonella spp. Salmonella Enteritidis and Salmonella Typhimurium, respectively, the two most clinically relevant serotypes. An internal amplification positive control was included in the experiment to ensure the optimal functioning of the PCR and detect possible PCR inhibition. Three sets of primers were used for the amplification of the target sequences. The results were compared to those of the Kauffmann-White antigenic classification scheme. Results The assay was 100% sensitive and specific, correctly identifying all 44 Salmonella strains, all 21 samples of S. Enteritidis and all 17 samples of S. Typhimurium tested in this work. Therefore, the entire experiment had specificity and sensitivity of 100%. The detection limit was down to 10 copies of DNA target per 25 μl reaction. Conclusion The assay can amplify and analyse a large number of samples in approximately 8 hours, compared to the 4 to 5 days conventional identification takes, and is thus considered a very promising method for detecting the two major serotypes of Salmonella quickly and accurately from clinical and environmental samples.Published versio

Meson exchange currents in electromagnetic one-nucleon emission

The role of meson exchange currents (MEC) in electron- and photon-induced one-nucleon emission processes is studied in a nonrelativistic model including correlations and final state interactions. The nuclear current is the sum of a one-body and of a two-body part. The two-body current includes pion seagull, pion-in-flight and the isobar current contributions. Numerical results are presented for the exclusive 16O(e,e'p)15N and 16O(\gamma,p)15N reactions. MEC effects are in general rather small in (e,e'p), while in (\gamma,p) they are always large and important to obtain a consistent description of (e,e'p) and (\gamma,p) data, with the same spectroscopic factors. The calculated (\gamma,p) cross sections are sensitive to short-range correlations at high values of the recoil momentum, where MEC effects are larger and overwhelm the contribution of correlations.Comment: 9 pages, 6 figure

Expression of Lineage Transcription Factors Identifies Differences in Transition States of Induced Human Oligodendrocyte Differentiation

Oligodendrocytes (OLs) are critical for myelination and are implicated in several brain disorders. Directed differentiation of human-induced OLs (iOLs) from pluripotent stem cells can be achieved by forced expression of different combinations of the transcription factors SOX10 (S), OLIG2 (O), and NKX6.2 (N). Here, we applied quantitative image analysis and single-cell transcriptomics to compare different transcription factor (TF) combinations for their efficacy towards robust OL lineage conversion. Compared with S alone, the combination of SON increases the number of iOLs and generates iOLs with a more complex morphology and higher expression levels of myelin-marker genes. RNA velocity analysis of individual cells reveals that S generates a population of oligodendrocyte-precursor cells (OPCs) that appear to be more immature than those generated by SON and to display distinct molecular properties. Our work highlights that TFs for generating iOPCs or iOLs should be chosen depending on the intended application or research question, and that SON might be beneficial to study more mature iOLs while S might be better suited to investigate iOPC biology

Cognitive and motivational monitoring during enriched sport activities in a sample of children living in Europe. The ESA program

Enriched Sport Activities (ESA) Program is an Evidence-based Practice Exercise Program cofounded by the Erasmus + Programme of the European Union (Key action: Sport-579661-EPP-1-2016-2-IT-SPO-SCP). It aims to enhance social inclusion, equal opportunities and psycho-physical wellbeing in children with typical development and special needs. This aim will be pursued through two ways: (1) Children and preadolescents’ participation in Enriched Sport Activities (ESA) Program; (2) Parents’ involvement and education on cognitive, motivational and social benefits of Physical Activities (PA) in their children. Recent research showed that high-level cognitive processes, such as inhibition, shifting, working memory and planning, can be improved by aerobic exercise programs following both single bouts of exercise and longer trainings from moderate to vigorous intensity [1]. Nevertheless, in the developmental age, structured sport activities, such as martial arts, basketball, soccer, rowing and dancing, act by delivering both physical and psychological benefits. The former involve physical fitness such as cardiorespiratory fitness, muscular strength, muscular endurance, flexibility and motor skills such as coordination, whilst the latter concern enjoyment, self-confidence and self-esteem, a sense of belonging and social support [2–4]. The effectiveness of PMA (Programma Motorio Arricchito), a structured motor program on coordination and executive functioning in kindergarten children, has been demonstrated [5]

Systematic Review of Explicit Instruments Measuring Nature Connectedness: What Do We Know and What is Next?

This systematic review assesses the methodological quality of manuscripts focusing on scales that explicitly measure nature connectedness. A literature search in six electronic databases was conducted using a search strategy based on PICO guidelines. Only peer-reviewed primary research available in English language, published between 2000 and 2021, meeting the scope of this review were included. Data from 35 studies were narratively analyzed. Their methodological quality was assessed using the COSMIN Risk of Bias checklist. Only five studies were rated as high/adequate quality. Based on the findings we make the following recommendations: (a) the need for the development of a more universal nature connectedness construct, (b) the requirement to increase the methodological quality of the scales, (c) the need to identify which the scales measure trait or state, (d) the need to increase the validate scales cross-culturally, and (e) the need to develop scales that can be employed with non-adult samples

Pairing in nuclear systems: from neutron stars to finite nuclei

We discuss several pairing-related phenomena in nuclear systems, ranging from superfluidity in neutron stars to the gradual breaking of pairs in finite nuclei. We focus on the links between many-body pairing as it evolves from the underlying nucleon-nucleon interaction and the eventual experimental and theoretical manifestations of superfluidity in infinite nuclear matter and of pairing in finite nuclei. We analyse the nature of pair correlations in nuclei and their potential impact on nuclear structure experiments. We also describe recent experimental evidence that points to a relation between pairing and phase transitions (or transformations) in finite nuclear systems. Finally, we discuss recent investigations of ground-state properties of random two-body interactions where pairing plays little role although the interactions yield interesting nuclear properties such as 0+ ground states in even-even nuclei.Comment: 74 pages, 33 figs, uses revtex4. Submitted to Reviews of Modern Physic