Seeded x-ray free-electron laser generating radiation with laser statistical properties

The invention of optical lasers led to a revolution in the field of optics and even to the creation of completely new fields of research such as quantum optics. The reason was their unique statistical and coherence properties. The newly emerging, short-wavelength free-electron lasers (FELs) are sources of very bright coherent extreme-ultraviolet (XUV) and x-ray radiation with pulse durations on the order of femtoseconds, and are presently considered to be laser sources at these energies. Most existing FELs are highly spatially coherent but in spite of their name, they behave statistically as chaotic sources. Here, we demonstrate experimentally, by combining Hanbury Brown and Twiss (HBT) interferometry with spectral measurements that the seeded XUV FERMI FEL-2 source does indeed behave statistically as a laser. The first steps have been taken towards exploiting the first-order coherence of FELs, and the present work opens the way to quantum optics experiments that strongly rely on high-order statistical properties of the radiation.Comment: 24 pages, 10 figures, 37 reference

ATLAS Simulation readiness for first data at LHC

The commissioning phase for the ATLAS experiment, in preparation for the new LHC machine to switch on, has presented challenges to nearly every aspect of the software development. The ATLAS simulation program, as a part of this phase, is now operational and fully functional within the ATLAS common software framework, Athena. The latest developments are directed towards enhanced versatility to cope with the increasing needs of developers and users and ease of use for the large ATLAS community, now with more than 2000 potential users. Emphasis in this talk is on recently added functionality recently added, validation and production strategy, and improved robustness and maintainability

The Dynamics of Poor Systems of Galaxies

We assemble and observe a sample of poor galaxy systems that is suitable for testing N-body simulations of hierarchical clustering (Navarro, Frenk, & White 1997; NFW) and other dynamical halo models (e.g., Hernquist 1990). We (1) determine the parameters of the density profile rho(r) and the velocity dispersion profile sigma(R), (2) separate emission-line galaxies from absorption-line galaxies, examining the model parameters and as a function of spectroscopic type, and (3) for the best-behaved subsample, constrain the velocity anisotropy parameter, beta, which determines the shapes of the galaxy orbits. The NFW universal profile and the Hernquist (1990) model both provide good descriptions of the spatial data. In most cases an isothermal sphere is ruled out. Systems with declining sigma(R) are well-matched by theoretical profiles in which the star-forming galaxies have predominantly radial orbits (beta > 0); many of these galaxies are probably falling in for the first time. There is significant evidence for spatial segregation of the spectroscopic classes regardless of sigma(R).Comment: 36 pages, 20 figures, and 5 tables. To appear in the Astrophysical Journa

Asymptotics for the number of eigenvalues of three-particle Schr\"{o}dinger operators on lattices

We consider the Hamiltonian of a system of three quantum mechanical particles (two identical fermions and boson)on the three-dimensional lattice $\Z^3$ and interacting by means of zero-range attractive potentials. We describe the location and structure of the essential spectrum of the three-particle discrete Schr\"{o}dinger operator $H_{\gamma}(K),$ $K$ being the total quasi-momentum and $\gamma>0$ the ratio of the mass of fermion and boson. We choose for $\gamma>0$ the interaction $v(\gamma)$ in such a way the system consisting of one fermion and one boson has a zero energy resonance. We prove for any $\gamma> 0$ the existence infinitely many eigenvalues of the operator $H_{\gamma}(0).$ We establish for the number $N(0,\gamma; z;)$ of eigenvalues lying below $z<0$ the following asymptotics $$\lim_{z\to 0-}\frac{N(0,\gamma;z)}{\mid \log \mid z\mid \mid}={U} (\gamma) .$$ Moreover, for all nonzero values of the quasi-momentum $K \in T^3$ we establish the finiteness of the number $N(K,\gamma;\tau_{ess}(K))$ of eigenvalues of $H(K)$ below the bottom of the essential spectrum and we give an asymptotics for the number $N(K,\gamma;0)$ of eigenvalues below zero.Comment: 25 page

Using XDAQ in Application Scenarios of the CMS Experiment

XDAQ is a generic data acquisition software environment that emerged from a rich set of of use-cases encountered in the CMS experiment. They cover not the deployment for multiple sub-detectors and the operation of different processing and networking equipment as well as a distributed collaboration of users with different needs. The use of the software in various application scenarios demonstrated the viability of the approach. We discuss two applications, the tracker local DAQ system for front-end commissioning and the muon chamber validation system. The description is completed by a brief overview of XDAQ.Comment: Conference CHEP 2003 (Computing in High Energy and Nuclear Physics, La Jolla, CA

Healthy Eating, Physical Activity, and Sleep Hygiene (HEPAS) as the Winning Triad for Sustaining Physical and Mental Health in Patients at Risk for or with Neuropsychiatric Disorders: Considerations for Clinical Practice

Neuropsychiatric disorders stem from gene-environment interaction and their development can be, at least in some cases, prevented by the adoption of healthy and protective lifestyles. Once full blown, neuropsychiatric disorders are prevalent conditions that patients live with a great burden of disability. Indeed, the determinants that increase the affliction of neuropsychiatric disorders are various, with unhealthy lifestyles providing a significant contribution in the interplay between genetic, epigenetic, and environmental factors that ultimately represent the pathophysiological basis of these impairing conditions. On one hand, the adoption of Healthy Eating education, Physical Activity programs, and Sleep hygiene promotion (HEPAS) has the potential to become one of the most suitable interventions to reduce the risk to develop neuropsychiatric disorders, while, on the other hand, its integration with pharmacological and psychological therapies seems to be essential in the overall management of neuropsychiatric disorders in order to reduce the disability and improve the quality of life of affected patients. We present an overview of the current evidence in relation to HEPAS components in the prevention and management of neuropsychiatric disorders and provide suggestions for clinical practice

Generalized Electromagnetic fields in Chiral Medium

The time dependent Dirac-Maxwell's Equations in presence of electric and magnetic sources are written in chiral media and the solutions for the classical problem are obtained in unique simple and consistent manner. The quaternion reformulation of generalized electromagnetic fields in chiral media has also been developed in compact, simple and consistent manner

Projective Invariance and One-Loop Effective Action in Affine-Metric Gravity Interacting with Scalar Field

We investigate the influence of the projective invariance on the renormalization properties of the theory. One-loop counterterms are calculated in the most general case of interaction of gravity with scalar field.Comment: 10 pages, LATE

Coagulation activation and inflammation in sickle cell disease-associated pulmonary hypertension

BACKGROUND: Pulmonary hypertension (PHT) is common in sickle cell disease (SCD). The purpose of this study was to determine whether markers of coagulation activation and inflammation are associated with PHT in SCD. DESIGN AND METHODS: This cross-sectional study was performed using a cohort of patients followed at an adult Sickle Cell Clinic. Pulmonary artery systolic pressure was determined by Doppler echocardiography, and the diagnosis of PHT was defined using age, sex and body mass index-adjusted reference ranges. Clinical laboratory examinations, including hematologic studies and biochemical tests, as well as various measures of coagulation activation, endothelial activation and inflammation, were conducted on SCD subjects and on healthy, race-matched control subjects without SCD. RESULTS: Patients with SCD (n=76) had higher plasma levels of markers of coagulation (thrombin-antithrombin complex, prothrombin fragment F1+2, D-dimer) and endothelial (soluble vascular endothelial cell adhesion molecule, sVCAM) activation compared with control subjects (n=6). SCD patients with PHT (n=26) had significantly higher levels of sVCAM compared with those patients without PHT (n=50). Although PHT patients showed increased plasma measures of coagulation activation, the differences were not statistically significant when compared to those of patients without PHT. HbSS patients with PHT also had a trend towards higher levels of other inflammatory cytokines (interleukins 6, 8 and 10) than HbSS patients without PHT. There was a modest negative correlation between hemoglobin and plasma measures of coagulation and endothelial activation, and modest positive correlations between markers of hemolysis and plasma measures of coagulation and endothelial activation. CONCLUSIONS: SCD patients with PHT have higher levels of markers of endothelial activation and other inflammatory markers than patients without PHT. A trend towards an increased level of markers of coagulation activation was observed in SCD patients with PHT compared with that in patients without PHT. Markers of hemolysis are associated with coagulation activation and endothelial dysfunction in SCD patients. Clinical trials of anticoagulants and anti-inflammatory agents are warranted in SCD patients with PHT

UV Circular Polarisation in Star Formation Regions : The Origin of Homochirality?

Ultraviolet circularly polarised light has been suggested as the initial cause of the homochirality of organic molecules in terrestrial organisms, via enantiomeric selection of prebiotic molecules by asymmetric photolysis. We present a theoretical investigation of mechanisms by which ultraviolet circular polarisation may be produced in star formation regions. In the scenarios considered here, light scattering produces only a small percentage of net circular polarisation at any point in space, due to the forward throwing nature of the phase function in the ultraviolet. By contrast, dichroic extinction can produce a fairly high percentage of net circular polarisation (∼10%) and may therefore play a key role in producing an enantiomeric excessPeer reviewe