19 research outputs found
Recommended from our members
Cooperative Adaptive Cruise Control (CACC) for Truck Platooning: Operational Concept Alternatives
Cooperative Adaptive Cruise Control (CACC) provides an intermediate step toward a longer-term vision of trucks operating in closely-coupled automated platoons. There are important distinctions between CACC and automated truck platooning. First, with CACC, only truck speed control will be automated, using vehicle to vehicle (V2V) communication to supplement forward sensors. The drivers will still be responsible for actively steering the vehicle, lane keeping, and monitoring roadway and traffic conditions. Second, while truck platooning systems have relied on a Constant Distance Gap (CDG) control strategy, CACC has relied on a Constant-Time Gap (CTG) control strategy, where the distance between vehicles is proportional to the speed. For these reasons, a series of trucks using CACC is referred to as a string, rather than a platoon. This report mainly focuses on describing the various CACC operational concept alternatives at the level of individual vehicles, local groups of vehicles and their drivers, and which alternatives should be employed in this research project. These operational concepts can be broken into four categories: string formation, steady-state cruising, string split maneuvers, and faults or abnormal operating conditions
Recommended from our members
Cooperative Adaptive Cruise Control (CACC) for Truck Platooning: Operational Concept Alternatives
Cooperative Adaptive Cruise Control (CACC) provides an intermediate step toward a longer-term vision of trucks operating in closely-coupled automated platoons. There are important distinctions between CACC and automated truck platooning. First, with CACC, only truck speed control will be automated, using vehicle to vehicle (V2V) communication to supplement forward sensors. The drivers will still be responsible for actively steering the vehicle, lane keeping, and monitoring roadway and traffic conditions. Second, while truck platooning systems have relied on a Constant Distance Gap (CDG) control strategy, CACC has relied on a Constant-Time Gap (CTG) control strategy, where the distance between vehicles is proportional to the speed. For these reasons, a series of trucks using CACC is referred to as a string, rather than a platoon. This report mainly focuses on describing the various CACC operational concept alternatives at the level of individual vehicles, local groups of vehicles and their drivers, and which alternatives should be employed in this research project. These operational concepts can be broken into four categories: string formation, steady-state cruising, string split maneuvers, and faults or abnormal operating conditions
Disruptive mutations in TANC2 define a neurodevelopmental syndrome associated with psychiatric disorders
Contains fulltext :
208995.pdf (publisher's version ) (Open Access
Statin and non-steroidal anti-inflammatory drug use in relation to clinical outcome among patients with Rai stage 0 chronic lymphocytic leukemia
Recommended from our members
Development of a Conditional Event-Free Survival Tool in Diffuse Large B-Cell Lymphoma
Disruptive mutations in TANC2 define a neurodevelopmental syndrome associated with psychiatric disorders
Postsynaptic density (PSD) proteins have been implicated in the pathophysiology of neurodevelopmental and psychiatric disorders. Here, we present detailed clinical and genetic data for 20 patients with likely gene-disrupting mutations in TANC2âwhose protein product interacts with multiple PSD proteins. Pediatric patients with disruptive mutations present with autism, intellectual disability, and delayed language and motor development. In addition to a variable degree of epilepsy and facial dysmorphism, we observe a pattern of more complex psychiatric dysfunction or behavioral problems in adult probands or carrier parents. Although this observation requires replication to establish statistical significance, it also suggests that mutations in this gene are associated with a variety of neuropsychiatric disorders consistent with its postsynaptic function. We find that TANC2 is expressed broadly in the human developing brain, especially in excitatory neurons and glial cells, but shows a more restricted pattern in Drosophila glial cells where its disruption affects behavioral outcomes