25 research outputs found
Finite-time ruin probability of aggregate Gaussian processes
Let (Sigma(n)(i)=1 lambda X-i(i)(t) - g(t), t is an element of [0, T]} be an aggregate Gaussian risk process with a trend g(t). We derive exact asymptotics of the finite-time ruin probability given by
P((sup)(t is an element of[0,T]) (Sigma(i=1) lambda X-i(i)(t) - g(t)) > u)
as u -> infinity for {X-i(t), t is an element of [0,T]}, i <= n, satisfying some asymptotic conditions. Further, we derive asymptotic results for the finite-time ruin probabilities of risk processes perturbed by an aggregate Gaussian process
The BSUIN project
Baltic Sea Underground Innovation Network (BSUIN) is an European Union funded project that
extends capabilities of underground laboratories. The aim of the project is to join efforts in making
the underground laboratories in the Baltic Sea Region’s more accessible for innovation, business
development and science by improving the availability of information about the underground
facilities, service offerings, user experience, safety and marketing.The development of standards
for the characterization of underground laboratories will allow to compared them with each other.
This will help you choose the best places for physical measurements such as neutrino physics or
searching for dark matter. The project concerns laboratories where so far no measurements have
been made, and even undergrounds where there are no organized laboratories yet.The description
of the BSUIN project and the first results of characterization of natural radioactive background in
underground laboratories will be presented ˙ The BSUIN Project is funded by Interreg Baltic Sea
funding cooperation [2]
A cost-utility analysis of cervical cancer vaccination in preadolescent Canadian females
<p>Abstract</p> <p>Background</p> <p>Despite the fact that approximately 70% of Canadian women undergo cervical cancer screening at least once every 3 years, approximately 1,300 women were diagnosed with cervical cancer and approximately 380 died from it in 2008. This study estimates the effectiveness and cost-effectiveness of vaccinating 12-year old Canadian females with an AS04-adjuvanted cervical cancer vaccine. The indirect effect of vaccination, via herd immunity, is also estimated.</p> <p>Methods</p> <p>A 12-health-state 1-year-cycle Markov model was developed to estimate lifetime HPV related events for a cohort of 12-year old females. Annual transition probabilities between health-states were derived from published literature and Canadian population statistics. The model was calibrated using Canadian cancer statistics. From a healthcare perspective, the cost-effectiveness of introducing a vaccine with efficacy against HPV-16/18 and evidence of cross-protection against other oncogenic HPV types was evaluated in a population undergoing current screening practices. The base-case analysis included 70% screening coverage, 75% vaccination coverage, 18,672-$31,687 per QALY-gained, the lower range representing inclusion of cross-protective efficacy and herd immunity. The cost per QALY-gained was most sensitive to duration of vaccine protection, discount rate, and the correlation between probability of screening and probability of vaccination.</p> <p>Conclusion</p> <p>In the context of current screening patterns, vaccination of 12-year old Canadian females with an ASO4-ajuvanted cervical cancer vaccine is estimated to significantly reduce cervical cancer and mortality, and is a cost-effective option. However, the economic attractiveness of vaccination is impacted by the vaccine's duration of protection and the discount rate used in the analysis.</p
Helium burning and neutron sources in the stars
Helium burning represents an important stage of stellar evolution as it contributes to the synthesis of key elements such as carbon, through the triple-alfa process, and oxygen, through the 12C(alfa, gamma)16O reaction. It is the ratio of carbon to oxygen at the end of the helium burning stage that governs the following phases of stellar evolution leading to different scenarios depending on the initial stellar mass. In addition, helium burning in Asymptotic Giant Branch stars, provides the two main sources of neutrons, namely the 13C(alfa, n)16O and the 22Ne(alfa, n)25Mg, for the synthesis of about half of all elements heavier than iron through the s-process. Given the importance of these reactions, much experimental work has been devoted to the study of their reaction rates over the last few decades. However, large uncertainties still remain at the energies of astrophysical interest which greatly limit the accuracy of stellar models predictions. Here, we review the current status on the latest experimental efforts and show how measurements of these important reaction cross sections can be significantly improved at next-generation deep underground laboratories
Methods for Health Economic Evaluation of Vaccines and Immunization Decision Frameworks: A Consensus Framework from a European Vaccine Economics Community
Experimental behaviour of anchor bolts under pullout and relaxation tests
International audienc
Comparison of grain size distribution of loess soils measured with areometric and laser methods
Factors affecting the development and quality of bolts and screws
26.00; Translated from Polish (Wiad. Hutn. 1986 (6) p. 115-120)SIGLEAvailable from British Library Document Supply Centre- DSC:9022.06(BISI--26143)T / BLDSC - British Library Document Supply CentreGBUnited Kingdo