923 research outputs found
Study of non-collinear parton dynamics in the prompt photon photoproduction at HERA
We investigate the prompt photon photoproduction at HERA within the framework
of kt-factorization QCD approach. Our consideration is based on the off-shell
matrix elements for the underlying partonic subprocesses. The unintegrated
parton densities in a proton and in a photon are determined using the
Kimber-Martin-Ryskin (KMR) prescription. Additionally, we use the CCFM-evolved
unintegrated gluon as well as valence and sea quark distributions in a proton.
A conservative error analisys is performed. Both inclusive and associated with
the hadronic jet production rates are investigated. The theoretical results are
compared with the recent experimental data taken by the H1 and ZEUS
collaborations. We study also the specific kinematical properties of the
photon-jet system which are strongly sensitive to the transverse momentum of
incoming partons. Using the KMR scheme, the contribution from the quarks
emerging from the earlier steps of the parton evolution is estimated and found
to be of 15 - 20 approximately.Comment: 22 pages, 13 figures, 2 tabl
Two-Allergen Model Reveals Complex Relationship between IgE Crosslinking and Degranulation
SummaryAllergy is an immune response to complex mixtures of multiple allergens, yet current models use a single synthetic allergen. Multiple allergens were modeled using two well-defined tetravalent allergens, each specific for a distinct IgE, thus enabling a systematic approach to evaluate the effect of each allergen and percentage of allergen-specific IgE on mast cell degranulation. We found the overall degranulation response caused by two allergens is additive for low allergen concentrations or low percent specific IgE, does not change for moderate allergen concentrations with moderate to high percent specific IgE, and is reduced for high allergen concentrations with moderate to high percent specific IgE. These results provide further evidence that supraoptimal IgE crosslinking decreases the degranulation response and establishes the two-allergen model as a relevant experimental system to elucidate mast cell degranulation mechanisms
IoT (Internet of Things) and DfPL (Device-free Passive Localisation) in a disaster management scenario
Insulin-like growth factor-1 in CNS and cerebrovascular aging
Insulin-like growth factor-1 (IGF-1) is an important anabolic hormone that decreases with age. In the past two decades, extensive research has determined that the reduction in IGF-1 is an important component of the age-related decline in cognitive function in multiple species including humans. Deficiency in circulating IGF-1 results in impairment in processing speed and deficiencies in both spatial and working memory. Replacement of IGF-1 or factors that increase IGF-1 to old animals and humans reverses many of these cognitive deficits. Despite the overwhelming evidence for IGF-1 as an important neurotrophic agent, the specific mechanisms through which IGF-1 acts have remained elusive. Recent evidence indicates that IGF-1 is both produced by and has important actions on the cerebrovasculature as well as neurons and glia. Nevertheless, the specific regulation and actions of brain- and vascular-derived IGF-1 is poorly understood. The diverse effects of IGF-1 discovered thus far reveal a complex endocrine and paracrine system essential for integrating many of the functions necessary for brain health. Identification of the mechanisms of IGF-1 actions will undoubtedly provide critical insight into regulation of brain function in general and the causes of cognitive decline with age
Multi-gluon helicity amplitudes with one off-shell leg within high energy factorization
Basing on the Slavnov-Taylor identities, we derive a new prescription to
obtain gauge invariant tree-level scattering amplitudes for the process g*g->Ng
within high energy factorization. Using the helicity method, we check the
formalism up to several final state gluons, and we present analytical formulas
for the the helicity amplitudes for N=2. We also compare the method with
Lipatov's effective action approach.Comment: 25 pages, quite a few figures, an appendix added, typos correcte
Autonomic dysregulation and self‐injurious thoughts and behaviours in children and young people: A systematic review and meta‐analysis
Background: self-injurious thoughts and behaviours (SITBs) have been associated with dysfunction of the Autonomic Nervous System (ANS) in children and young people, suggesting that objective ANS measures may aid assessment of suicide risk, but a systematic synthesis of this literature is currently lacking.Methods: following a pre-registered protocol (PROSPERO CRD42022327605), we conducted a systematic search of PubMed, Medline, Embase, PsycINFO, and Web of Science, for empirical studies published until 10th May 2022 that compared indices of ANS functioning in individuals aged 0–25 years with versus without SITBs, or reported continuous associations between ANS measures and SITBs. Study quality was assessed with the Newcastle-Ottawa Scales. Pooled effect sizes (Hedge's g) were estimated with random-effects meta-analytic models.Results: twenty studies (1979 participants) were included in our systematic review, with 16 included in meta-analyses. Results suggested that SITBs were associated with altered cardiac indices of arousal (g = −0.328, p < 0.001), which was driven by lower heart rate variability in individuals with SITBs (g = −0.375, p = 0.025). Overall results for electrodermal activity were not significant (g = 0.026, p = 0.857), but subgroup analyses showed increased activity in studies of individuals who engaged specifically in non-suicidal self-harm (g = 0.249, p = 0.014) but decreased activity in the remaining studies (g = −0.567, p = 0.004).Conclusions: our systematic review and meta-analysis found evidence of reduced parasympathetic regulation as well as more tentative evidence of altered electrodermal activity in children and young people displaying SITBs. Future longitudinal studies should test the clinical utility of these markers for detecting and monitoring suicide risk
Non-linear evolution in CCFM: The interplay between coherence and saturation
We solve the CCFM equation numerically in the presence of a boundary
condition which effectively incorporates the non-linear dynamics. We retain the
full dependence of the unintegrated gluon distribution on the coherence scale,
and extract the saturation momentum. The resulting saturation scale is a
function of both rapidity and the coherence momentum. In Deep Inelastic
Scattering this will lead to a dependence of the saturation scale on the photon
virtuality in addition to the usual x-Bjorken dependence. At asymptotic
energies the interplay between the perturbative non-linear physics, and that of
the QCD coherence, leads to an interesting and novel dynamics where the
saturation momentum itself eventually saturates. We also investigate various
implementations of the "non-Sudakov" form factor. It is shown that the
non-linear dynamics leads to almost identical results for different form
factors. Finally, different choices of the scale of the running coupling are
analyzed and implications for the phenomenology are discussed.Comment: 37 pages, 21 figure
Polygenic scores for smoking and educational attainment have independent influences on academic success and adjustment in adolescence and educational attainment in adulthood
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