98 research outputs found

    Low serum albumin and the acute phase response predict low serum selenium in HIV-1 infected women

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    BACKGROUND: Low serum selenium has been associated with lower CD4 counts and greater mortality among HIV-1-seropositive individuals, but most studies have not controlled for serum albumin and the presence of an acute phase response. METHODS: A cross-sectional study was conducted to evaluate relationships between serum selenium concentrations and CD4 count, plasma viral load, serum albumin, and acute phase response markers among 400 HIV-1-seropositive women. RESULTS: In univariate analyses, lower CD4 count, higher plasma viral load, lower albumin, and the presence of an acute phase response were each significantly associated with lower serum selenium concentrations. In multivariate analyses including all four of these covariates, only albumin remained significantly associated with serum selenium. For each 0.1 g/dl increase in serum albumin, serum selenium increased by 0.8 μg/l (p < 0.001). Women with an acute phase response also had lower serum selenium (by 5.6 μg/l, p = 0.06). CONCLUSION: Serum selenium was independently associated with serum albumin, but not with CD4 count or plasma viral load, in HIV-1-seropositive women. Our findings suggest that associations between lower serum selenium, lower CD4 count, and higher plasma viral load may be related to the frequent occurrence of low serum albumin and the acute phase response among individuals with more advanced HIV-1 infection

    Maroon Archaeology Beyond the Americas: A View From Kenya

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    Archaeological research on Maroons—that is, runaway slaves—has been largely confined to the Americas. This essay advocates a more global approach. It specifically uses two runaway slave communities in 19th-century coastal Kenya to rethink prominent interpretive themes in the field, including “Africanisms,” Maroons’ connections to indigenous groups, and Maroon group cohesion and identity. This article’s analysis demonstrates that the comparisons enabled by a more globalized perspective benefit the field. Instead of eliding historical and cultural context, these comparisons support the development of more localized and historically specific understandings of individual runaway slave communities both in Kenya and throughout the New World

    Nothing Lasts Forever: Environmental Discourses on the Collapse of Past Societies

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    The study of the collapse of past societies raises many questions for the theory and practice of archaeology. Interest in collapse extends as well into the natural sciences and environmental and sustainability policy. Despite a range of approaches to collapse, the predominant paradigm is environmental collapse, which I argue obscures recognition of the dynamic role of social processes that lie at the heart of human communities. These environmental discourses, together with confusion over terminology and the concepts of collapse, have created widespread aporia about collapse and resulted in the creation of mixed messages about complex historical and social processes

    An early type of post-medieval toothbrush?

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    Dendrochronological dating of wood from the Fountain of Youth Park Archaeological site (8SJ31), St. Augustine, Florida, U.S.A.

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    Settled in 1565 by the Pedro Mene´ndez de Aviles expedition, St. Augustine, Florida, holds great educational, historical, and anthropological interest for current researchers as the oldest continuously occupied European community in the continental United States. Archaeological excavations produced two large (ca. 20 cm diameter) posts from the Fountain of Youth Archaeological Park site. Our objective in this project was to use tree-ring dating to determine the outermost dates of the two posts and to use these dates to assist archaeological interpretations. Sample 8SJ31-2741 was pine and contained tree rings that were successfully crossdated using the Lake Louise reference chronology from southern Georgia to AD 1620–1668. Sample 8SJ31-2766 was a cypress sample that we could not crossdate using a nearby reference chronology from the Altamaha River in southern Georgia. The date for sample 8SJ31-2741 places its cutting and deposition within the Mission Period occupation and verifies that the Nombre de Dios mission village was still active and building after 1668 into the late 17th Century. Furthermore, the dendrochronological date confirmed the stratigraphic interpretation, suggesting that disturbance of the upper layers of the surface in this part of the site was perhaps not as disruptive to the soils as originally assumed. This project demonstrates the feasibility of dating wood extracted from sites from the historic Spanish-era period in the Southeastern US.This item is part of the Tree-Ring Research (formerly Tree-Ring Bulletin) archive. For more information about this peer-reviewed scholarly journal, please email the Editor of Tree-Ring Research at [email protected]
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