The Influence of High Density Grazing and Conventional, Rotational Grazing on Soil And Vegetation Parameters in the Semi-Arid and Mesic Grasslands of South Africa

In South Africa, multi-camp rotational grazing using ‘conservative stocking rates’ have been the conventional approach to livestock grazing management systems. However, as of late, the high-desnity approach (used interchangeably – depending on the situation – with regenerative grazing, mob grazing, short duration, high pressure grazing, rapid rotation, time controlled, ultra-high density, holistic grazing and holistic resource management) has been adopted by numerous farmers. This approach is considered to be an adaptable one, incorporating the ‘herd effect’ concept, whereby large numbers of animals occupy an area for short periods of time, and allowed an extended rest period. It claims to improve rangeland productivity by improving both vegetation and soil condition, and, in turn, enhancing animal productivity. However, scientifically sound information regarding these claims, as well as the influences of this strategy opposed to the conventional rotational systems in South Africa is somewhat lacking. The aim of our research is to explore the different facets of regenerative grazing, practiced by various livestock farmers in natural veld in the semi-arid and mesic grasslands of South Africa. These facets include different soil (physical and chemical parameters), vegetation (composition, dry matter production, necromass, cover and quality (i.e. crude protein (CP), neutral detergent fibre (NDF), acid detergent fibre (ADF), acid detergent lignin (ADL) and organic matter (OM)), animal and human (decision-making and financials) interactions and dynamics, in comparison to conventional, rotational grazing. Due to preliminary trials, only the forage quality parameters will be discussed. These parameters have been shown to differ between the two different grazing management strategies on a farm scale, however, not on a spatial scale. This project has the potential to produce scientific and objective information on the functionality of different grazing systems in the grasslands of South Africa, and it can, too, assist livestock farmers in understanding the rationale behind high pressure grazing

Finding essentiality feasible: common questions and misinterpretations concerning the “essential-use” concept

The essential-use concept is a tool that can guide the phase-out of per- and polyfluoroalkyl substances (PFAS) and potentially other substances of concern. This concept is a novel approach to chemicals management that determines whether using substances of concern, such as PFAS, is truly essential for a given functionality. To assess the essentiality of a particular use case, three considerations need to be addressed: (1) the function (chemical, end use and service) that the chemical provides in the use case, (2) whether the function is necessary for health and safety and critical for the functioning of society and (3) if the function is necessary, whether there are viable alternatives for the chemical for this particular use. A few illustrative examples of the three-step process are provided for use cases of PFAS. The essential-use concept takes chemicals management away from a substance-by-substance approach to a group approach. For PFAS and other substances of concern, it offers a more rapid pathway toward effective management or phase-out. Parts of the concept of essential use have already been widely applied in global treaties and international regulations and it has also been recently used by product manufacturers and retailers to phase out substances of concern from supply chains. Herein some of the common questions and misinterpretations regarding the practical application of the essential-use concept are reviewed, and answers and further clarifications are provided

Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications

This work was supported by a restricted research grant of Bayer AG

Finding essentiality feasible: common questions and misinterpretations concerning the "essential-use" concept

The essential-use concept is a tool that can guide the phase-out of per- and polyfluoroalkyl substances (PFAS) and potentially other substances of concern. This concept is a novel approach to chemicals management that determines whether using substances of concern, such as PFAS, is truly essential for a given functionality. To assess the essentiality of a particular use case, three considerations need to be addressed: (1) the function (chemical, end use and service) that the chemical provides in the use case, (2) whether the function is necessary for health and safety and critical for the functioning of society and (3) if the function is necessary, whether there are viable alternatives for the chemical for this particular use. A few illustrative examples of the three-step process are provided for use cases of PFAS. The essential-use concept takes chemicals management away from a substance-by-substance approach to a group approach. For PFAS and other substances of concern, it offers a more rapid pathway toward effective management or phase-out. Parts of the concept of essential use have already been widely applied in global treaties and international regulations and it has also been recently used by product manufacturers and retailers to phase out substances of concern from supply chains. Herein some of the common questions and misinterpretations regarding the practical application of the essential-use concept are reviewed, and answers and further clarifications are provided