Defining frequency domain performance of analog-to-information converters

Peer Reviewe

MRI findings in a patient with glossopharyngeal neuralgia.

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A New Surgical Approach for Direct Acoustic Cochlear Implant: A Temporal Bone Study

The direct acoustic cochlear implant (DACI) is among the latest developments in the field of implantable acoustic prostheses. The surgical procedure requires a mastoidectomy and a posterior-inferior tympanotomy, with access to the facial recess at the level of the oval window, in a complex and lengthy surgical approach. Here, we report a new and considerably shorter surgical approach

Reducing parasitic resonances in particle accelerators components by broadband Higher Order Mode couplers

In particle accelerator components, parasitic resonances must be reduced because they heat up the equipment and cause beam instabilities. In this paper, a method for designing and characterizing Higher Order Mode (HOM) couplers for reducing such resonances in a broad bandwidth is proposed. A case study is considered for a specific component, called QuattroTank, showing geometrical discontinuities and thus causing significant electro-magnetic resonances. Results of numerical simulation and experimental emulation prove the capability of the proposed method to reduce the peaks and the $Q-factor of the resonances

Idiopathic sensorineural hearing loss in the only hearing ear

A retrospective chart review was used for 31 patients with sudden, progressive or fluctuating sensorineural hearing loss (SHL) in the only hearing ear who had been consecutively evaluated at the ENT, Audiology and Phoniatrics Unit of the University of Pisa. The group of patients was evaluated with a complete history review, clinical evaluation, imaging exam (MRI, CT), audiologic tests (tone and speech audiometry, tympanometry, study of stapedial reflexes, ABR and otoacoustic emission) evaluation. In order to exclude genetic causes, patients were screened for CX 26 and CX30 mutations and for mitochondrial DNA mutation A1555G. Patients with sudden or rapidly progressive SHL in the only hearing ear were treated with osmotic diuretics and corticosteroids. In patients who did not respond to intravenous therapy we performed intratympanic injections of corticosteroid. Hearing aids were fitted when indicated and patients who developed severe to profound SHL were scheduled for cochlear implant surgery. The aim of this study is to report and discuss the epidemiology, aetiopathogenesis, therapy and clinical characteristic of patients affected by SHL in the only hearing hear and to discuss the issues related to the cochlear implant procedure in some of these patients, with regard to indications, choice of the ear to implant and results

Cochlear implant in incomplete partition type I

In this investigation, we report on 4 patients affected by incomplete partition type I submitted to cochlear implant at our institutions. Preoperative, surgical, mapping and follow-up issues as well as results in cases with this complex malformation are described. The cases reported in the present study confirm that cochlear implantation in patients with incomplete partition type I may be challenging for cochlear implant teams. The results are variable, but in many cases satisfactory, and are mainly related to the surgical placement of the electrode and residual neural nerve fibres. Moreover, in some cases the association of cochlear nerve abnormalities and other disabilities may significantly affect results

Learning the optimal Tikhonov regularizer for inverse problems

Publisher Copyright: © 2021 Neural information processing systems foundation. All rights reserved.In this work, we consider the linear inverse problem y = Ax+ε, where A: X → Y is a known linear operator between the separable Hilbert spaces X and Y, x is a random variable in X and ε is a zero-mean random process in Y . This setting covers several inverse problems in imaging including denoising, deblurring and X-ray tomography. Within the classical framework of regularization, we focus on the case where the regularization functional is not given a priori, but learned from data. Our first result is a characterization of the optimal generalized Tikhonov regularizer, with respect to the mean squared error. We find that it is completely independent of the forward operator A and depends only on the mean and covariance of x. Then, we consider the problem of learning the regularizer from a finite training set in two different frameworks: one supervised, based on samples of both x and y, and one unsupervised, based only on samples of x. In both cases we prove generalization bounds, under some weak assumptions on the distribution of x and ε, including the case of sub-Gaussian variables. Our bounds hold in infinite-dimensional spaces, thereby showing that finer and finer discretizations do not make this learning problem harder. The results are validated through numerical simulations.Peer reviewe

COVID-19 Pandemic and Head and Neck Surgery Residency Program: Proposals for the "Phase 2"

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Impact of the COVID-19 Pandemic on Otolaryngology Residency: A Real-Life Experience

The coronavirus disease (COVID-19) pandemic as been rapidly spreading worldwide. In our country, the entire Italian Healthcare System has been forced to adapt to this unprecedented condition in this century. The Head and Neck Department clinical and surgical activity was substantially reduced. In this situation, the Ear, Nose and Throat (ENT) residents in University Hospitals find themselves in an uncertain position; we are physicians, facing a deadly disease about which much remains unknown, but we are also trainees, and there is a high risk for our residency training to be affected. With this Letter, we would like to give a testimony of our experience and give some advices to bridge the training gap