Computational investigation of wall shear stress-driven in-stent restenosis

C

Diagnostic imaging for hepatocellular carcinoma

Hepatocellular carcinoma (HCC) occurs mostly in individuals with cirrhosis, which is why the guidelines of the most important scientific societies indicate that these patients are included in surveillance programs through the repetition of an ultrasound examination every 6 months. The aim is to achieve early identification of the neoplasia in order to increase the possibility of curative therapies (liver transplantation, surgery or local ablative therapies) and to increase patient survival. HCC nodules arising in cirrhotic livers show characteristic angiographic behavior that can be evaluated with dynamic multidetector computed tomography and dynamic magnetic resonance imaging (MRI). However, the use of these techniques in real life is often hindered by the lack of uniform terminology in reporting and in the interpretation of the exams reflected in the impossibility of comparing examinations performed in different centers and/or at different times. Liver Imaging Reporting and Data System® was created to standardize reporting and data collection of computed tomography and MRI for HCC. In some cases HCC arises in patients with healthy livers and, although there is evidence that angiographic behavior is not different from cirrhotic patients in this clinical situation, the guidelines still indicate the execution of a biopsy. Frequent use of palliative therapeutic techniques such as transarterial chemoembolization, transarterial radioembolization or administration of antiangiogenic drugs (sorafenib) poses problems of interpretation of the therapeutic response with repercussions on the subsequent choices that have been attempted to resolve with the use of stringent criteria such as Modified Response Evaluation Criteria In Solid Tumors

On Productivity Measurement and Interpretation: Some Insights on Italy in the European Context. LEQS Paper No. 142/2019 March 2019

Over the period 1995–2016, the Italian performance in terms of productivity was poor in historical terms and in comparison with its main international partners. This issue goes beyond Italy, with declining productivity growth observed, from the second half of the nineties, in several other advanced economies. Possible explanations for the slowdown include factors such as lower capital investment by firms, decreased competition, excessive regulation, and capital misallocation. The diffuse slowing rates of measured productivity growth has also raised questions on whether GDP and output current compilation methods are adequate (i.e. the mis-measurement hypothesis). The “ICT revolution” has created new ways of exchanging and providing goods and services as result of increased connectivity. These developments challenge the way economic activity is traditionally measured. There are also measurement problems associated with estimating output and input volumes especially related to the quality of price indexes for some products and services. These problems have an impact on productivity estimates and might impair international comparability. In this paper, we intend to investigate what the core problems in productivity measurement and interpretation are in the European context, with a specific focus on Italy

Stochastic Ising model with flipping sets of spins and fast decreasing temperature

This paper deals with the stochastic Ising model with a temperature shrinking to zero as time goes to infinity. A generalization of the Glauber dynamics is considered, on the basis of the existence of simultaneous flips of some spins. Such dynamics act on a wide class of graphs which are periodic and embedded in $\mathbb{R}^d$. The interactions between couples of spins are assumed to be quenched i.i.d. random variables following a Bernoulli distribution with support $\{-1,+1\}$. The specific problem here analyzed concerns the assessment of how often (finitely or infinitely many times, almost surely) a given spin flips. Adopting the classification proposed in \cite{GNS}, we present conditions in order to have models of type $\mathcal{F}$ (any spin flips finitely many times), $\mathcal{I}$ (any spin flips infinitely many times) and $\mathcal{M}$ (a mixed case). Several examples are provided in all dimensions and for different cases of graphs. The most part of the obtained results holds true for the case of zero-temperature and some of them for the cubic lattice $\mathbb{L}_d=(\mathbb{Z}^d, \mathbb{E}_d)$ as well.Comment: 31 pages, 6 figures, Accepted for publication in "Annales de l'Institut Henri Poincar\'e, Probabilit\'es et Statistiques