2,422 research outputs found
The long way to innovation adoption: insights from precision agriculture
The adoption of innovations may boost the transition to sustainable agricultural models. Among these innovations, precision farming offers a fundamental contribution to sustainable soil management and the improvement in product quality. The work is set against this background and aims to analyse the rate of introducing precision farming tools and the variables that prevent/facilitate this adoption. Although adoption rates in Italy remain relatively low, it is vital to underline the obstacles that limit the broader use of precision agricultural technologies inside farms. To this end, the literature has highlighted various elements of complexity (farm characteristics, socio-economic and psychological), which can hinder or generate perceived complexity and significantly reduce the potential for technology adoption. In this context emerges the increasing importance of public and private activities related to knowledge transfer. The paper focuses on agricultural knowledge and innovation systems, which are also relevant in light of the recent proposal for the new regulation on rural development. The awareness-knowledge-adoption-product (AKAP) sequence was used to reveal the gap between the potential and actual adoption of innovation on Italian farms to comprehend the adoption process and identify relevant barriers and the role knowledge systems played. Empirical findings show that AKIS has a critical mediating function in promoting innovation uptake. Strengthening knowledge systems, acting on the different phases of the AKAP sequence, could allow a greater understanding of precision agriculture techniques and bottlenecks to adoption
The leading role of perception: the FACOPA model to comprehend innovation adoption
none5noIn this work, we explore the link between the perception of complexity and the possibility of adopting precision agricultural tools (PATs). Many studies have analysed the role of perception, mostly considering it a determinant of adoption on the same level as other contextual factors. In contrast, this study contributes by assuming that farmers' perceived complexity is the main factor influencing their propensity to innovate and should be analysed on a different level. Starting from this assumption, a new theoretical model is proposed with the aim of studying the “factors–perception of complexity–adoption” (FACOPA) process. To test the validity of our hypothesis, a survey is conducted based on a purposive sample of 285 farmers. First, a linear regression model permits us to identify determinants of the perception of complexity. Then, a multinomial logistic model is used to determine which aspects of perceived complexity may affect the choice to adopt precision farming tools made by three different types of agricultural entrepreneurs: adopters, non-adopters, and planners. First, the linear regression results show that socio-structural variables have a logical relationship with perceived complexity, with age, farm size, the intensity of information and the intensity of work being significant. Then, the multinomial logistic model highlights that non-adopters perceive almost all aspects of complexity as barriers to adoption. Planners show a lower perception of complexity than non-adopters, with complexity being determined by financial and network aspects. The results provide interesting suggestions for policy-makers. Indeed, the FACOPA model offers insights into an intervention framework in which policy measures can be diversified to disseminate PATs based on farmer categories. Non-adopters require a broader set of policy instruments, while planners should be encouraged to become adopters through financial support and the activation of innovation networks.openVecchio Y.; De Rosa M.; Pauselli G.; Masi M.; Adinolfi F.Vecchio Y.; De Rosa M.; Pauselli G.; Masi M.; Adinolfi F
The Reciprocal Influence Criterion: An Upgrade of the Information Quality Ratio
Understanding and quantifying the mutual influence between systems remain crucial but challenging tasks in any scientific enterprise. The Pearson correlation coefficient, the mutual information, and the information quality ratio are the most widely used indicators, only the last two being valid for nonlinear interactions. Given their limitations, a new criterion is proposed, the reciprocal influence criterion, which is very simple conceptually and does not make any assumption about the statistics of the stochastic variables involved. In addition to being normalised as the information quality ratio, it provides a much better resilience to noise and much higher stability to the issues related to the determination of the involved probability distribution functions. A conditional version, to counteract the effects of confounding variables, has also been developed, showing the same advantages compared to the more traditional indicators. A series of systematic tests with numerical examples is reported, to compare the properties of the new indicator with the more traditional ones, proving its clear superiority in practically all respects
Large deviations for the macroscopic motion of an interface
We study the most probable way an interface moves on a macroscopic scale from an initial to a final position within a fixed time in the context of large deviations for a stochastic microscopic lattice system of Ising spins with Kac interaction evolving in time according to Glauber (non-conservative) dynamics. Such interfaces separate two stable phases of a ferromagnetic system and in the macroscopic scale are represented by sharp transitions. We derive quantitative estimates for the upper and the lower bound of the cost functional that penalizes all possible deviations and obtain explicit error terms which are valid also in the macroscopic scale. Furthermore, using the result of a companion paper about the minimizers of this cost functional for the macroscopic motion of the interface in a fixed time, we prove that the probability of such events can concentrate on nucleations should the transition happen fast enough
Development of large radii half-wave plates for CMB satellite missions
The successful European Space Agency (ESA) Planck mission has mapped the
Cosmic Microwave Background (CMB) temperature anisotropy with unprecedented
accuracy. However, Planck was not designed to detect the polarised components
of the CMB with comparable precision. The BICEP2 collaboration has recently
reported the first detection of the B-mode polarisation. ESA is funding the
development of critical enabling technologies associated with B-mode
polarisation detection, one of these being large diameter half-wave plates. We
compare different polarisation modulators and discuss their respective
trade-offs in terms of manufacturing, RF performance and thermo-mechanical
properties. We then select the most appropriate solution for future satellite
missions, optimized for the detection of B-modes.Comment: 16 page
Multi-mode TES bolometer optimization for the LSPE-SWIPE instrument
In this paper we explore the possibility of using transition edge sensor
(TES) detectors in multi-mode configuration in the focal plane of the Short
Wavelength Instrument for the Polarization Explorer (SWIPE) of the
balloon-borne polarimeter Large Scale Polarization Explorer (LSPE) for the
Cosmic Microwave Background (CMB) polarization. This study is motivated by the
fact that maximizing the sensitivity of TES bolometers, under the augmented
background due to the multi-mode design, requires a non trivial choice of
detector parameters. We evaluate the best parameter combination taking into
account scanning strategy, noise constraints, saturation power and operating
temperature of the cryostat during the flight.Comment: in Journal of Low Temperature Physics, 05 January 201
<b><i>Topoisomerase 1</i></b> Promoter Variants and Benefit from Irinotecan in Metastatic Colorectal Cancer Patients
Objective: Topoisomerase 1 (topo-1) is an important target for the treatment of metastatic colorectal cancer (CRC). The aim of the present study was to evaluate the correlation between topo-1 single-nucleotide polymorphisms (SNPs) and clinical outcome in metastatic CRC (mCRC) patients.
Methods: With the use of specific software (PROMO 3.0), we performed an in silico analysis of topo-1 promoter SNPs; the rs6072249 and rs34282819 SNPs were included in the study. DNA was extracted from 105 mCRC patients treated with FOLFIRI ± bevacizumab in the first line. SNP genotyping was performed by real-time PCR. Genotypes were correlated with clinical parameters (objective response rate, progression-free survival, and overall survival).
Results: No single genotype was significantly associated with clinical variables. The G allelic variant of rs6072249 topo-1 SNP is responsible for GC factor and X-box-binding protein transcription factor binding. The same allelic variant showed a nonsignificant trend toward a shorter progression-free survival (GG, 7.5 months; other genotypes, 9.3 months; HR 1.823, 95% CI 0.8904-3.734; p = 0.1).
Conclusion: Further analyses are needed to confirm that the topo-1 SNP rs6072249 and transcription factor interaction could be a part of tools to predict clinical outcome in mCRC patients treated with irinotecan-based regimens
Evaluation of polygenic determinants of non-alcoholic fatty liver disease (NAFLD) by a candidate genes resequencing strategy
NAFLD is a polygenic condition but the individual and cumulative contribution of identified genes remains to be established. To get additional insight into the genetic architecture of NAFLD, GWAS-identified GCKR, PPP1R3B, NCAN, LYPLAL1 and TM6SF2 genes were resequenced by next generation sequencing in a cohort of 218 NAFLD subjects and 227 controls, where PNPLA3 rs738409 and MBOAT7 rs641738 genotypes were also obtained. A total of 168 sequence variants were detected and 47 were annotated as functional. When all functional variants within each gene were considered, only those in TM6SF2 accumulate in NAFLD subjects compared to controls (P = 0.04). Among individual variants, rs1260326 in GCKR and rs641738 in MBOAT7 (recessive), rs58542926 in TM6SF2 and rs738409 in PNPLA3 (dominant) emerged as associated to NAFLD, with PNPLA3 rs738409 being the strongest predictor (OR 3.12, 95% CI, 1.8-5.5, P 0.28 was associated with a 3-fold increased risk of NAFLD. Interestingly, rs61756425 in PPP1R3B and rs641738 in MBOAT7 genes were predictors of NAFLD severity. Overall, TM6SF2, GCKR, PNPLA3 and MBOAT7 were confirmed to be associated with NAFLD and a score based on these genes was highly predictive of this condition. In addition, PPP1R3B and MBOAT7 might influence NAFLD severity
Valutare l’investimento in sistemi ERP
Sulla scorta di esperienze com-
plementari, viene svolta l’anali-
si critica dei principali metodi
suggeriti in letteratura per la
valutazione di proposte di inve-
stimento in sistemi ERP. Oltre a
costruire uno stato dell’arte
utile ai cultori della materia, gli
autori giungono a prospettare
un diverso approccio per l’in-
quadramento dei costi e dei
benefici che in vario modo
vanno proiettivamente a connet-
tersi con l’installazione di un
sistema ER
Free Energy Minimizers for a Two--Species Model with Segregation and Liquid-Vapor Transition
We study the coexistence of phases in a two--species model whose free energy
is given by the scaling limit of a system with long range interactions (Kac
potentials) which are attractive between particles of the same species and
repulsive between different species.Comment: 32 pages, 1 fig, plain tex, typeset twic
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