Assessment Of Accessory Canals Of The Canalis Sinuosus: A Study Of 1000 Cone Beam Computed Tomography Examinations

The aim of this study was to verify the presence, spatial location, and calibre of the accessory canals (AC) of the canalis sinuosus by cone beam computed tomography, and their relationship to the anterior maxilla. This retrospective analysis included the scans of 1000 subjects. Parameters registered were sex, age, number of AC, presence or absence of AC with a diameter 1.0 mm), and AC location in relation to the adjacent teeth. Males showed a statistically higher frequency of AC than females. The difference in age distribution was not statistically significant. Twenty percent of all AC presented a diameter of a least 1.0 mm. The end of the AC trajectory was most frequently located palatal to the anterior maxillary teeth. All relationships analyzed here were very weak (age vs. number of AC, age vs. AC diameter, number of AC vs. sex). Overall, the results of this study showed that AC of the canalis sinuosus are a common anatomical structure in the anterior maxilla, regardless of age and sex. © 2016 International Association of Oral and Maxillofacial Surgeons45121586159

Effects Of Dextrose And Lipopolysaccharide On The Corrosion Behavior Of A Ti-6al-4v Alloy With A Smooth Surface Or Treated With Double-acid-etching

Diabetes and infections are associated with a high risk of implant failure. However, the effects of such conditions on the electrochemical stability of titanium materials remain unclear. This study evaluated the corrosion behavior of a Ti-6Al-4V alloy, with a smooth surface or conditioned by double-acid-etching, in simulated body fluid with different concentrations of dextrose and lipopolysaccharide. For the electrochemical assay, the open-circuit-potential, electrochemical impedance spectroscopy, and potentiodynamic test were used. The disc surfaces were characterized by scanning electron microscopy and atomic force microscopy. Their surface roughness and Vickers microhardness were also tested. The quantitative data were analyzed by Pearson's correlation and independent t-tests (α = 0.05). In the corrosion parameters, there was a strong lipopolysaccharide correlation with the I pass (passivation current density), Cdl (double-layer capacitance), and Rp (polarization resistance) values (p<0.05) for the Ti-6Al-4V alloy with surface treatment by double-acid-etching. The combination of dextrose and lipopolysaccharide was correlated with the I corr (corrosion current density) and Ipass (p<0.05). The acid-treated groups showed a significant increase in Cdl values and reduced Rp values (p<0.05, t-test). According to the topography, there was an increase in surface roughness (R2 = 0.726, p<0.0001 for the smooth surface; R2 = 0.405, p = 0.036 for the double-acid-etching-treated surface). The microhardness of the smooth Ti-6Al-4V alloy decreased (p<0.05) and that of the treated Ti-6Al-4V alloy increased (p<0.0001). Atomic force microscopy showed changes in the microstructure of the Ti-6Al-4V alloy by increasing the surface thickness mainly in the group associated with dextrose and lipopolysaccharide. The combination of dextrose and lipopolysaccharide affected the corrosion behavior of the Ti-6Al-4V alloy surface treated with double-acid-etching. However, no dose-response corrosion behavior could be observed. These results suggest a greater susceptibility to corrosion of titanium implants in diabetic patients with associated infections. © 2014 Faverani et al.93Udupa, A., Nahar, P., Shah, S., Kshirsagar, M., Ghongane, B., A comparative study of effects of Omega-3 fatty acids, alpha lipoic acid and vitamin E in Type 2 diabetes mellitus (2013) Ann Med Health Sci Res, 3, pp. 442-446Engebretson, S., Gelato, M., Hyman, L., Michalowicz, B.S., Design features of the Diabetes and Periodontal Therapy Trial (DPTT): A multicenter randomized single-masked clinical trial testing the effect of nonsurgical periodontal therapy on glycosylated hemoglobin (HbA1c) levels in subjects with type 2 diabetes and chronic periodontitis (2013) Contemp Clin Trials, 36, pp. 515-526. , DPTT study groupAkca, K., Sarac, E., Baysal, U., Fanuscu, M., Chang, T.L., Micromorphologic changes around biophysically-stimulated titanium implants in ovariectomized rats (2007) Head Face Med, 3, p. 28Nelson, R.G., Shlossman, M., Budding, L.M., Pettitt, D.J., Saad, M.F., Genco, R.J., Knowler, W.C., Periodontal disease and NIDDM in Pima Indians (1990) Diabetes Care, 13 (8), pp. 836-840Oates, T.W., Huynh-Ba, G., Vargas, A., Alexander, P., Feine, J., A critical review of diabetes, glycemic control, and dental implant therapy (2013) Clin Oral Implants Res, 24, pp. 117-127Manfredi, M., McCullough, M.J., Vescovi, P., Al-Kaarawi, Z.M., Porter, S.R., Update on diabetes mellitus and related oral diseases (2004) Oral Diseases, 10 (4), pp. 187-200. , DOI 10.1111/j.1601-0825.2004.01019.xSkamagas, M., Breen, T.L., LeRoith, D., Update on diabetes mellitus: Prevention, treatment, and association with oral diseases (2008) Oral Diseases, 14 (2), pp. 105-114. , DOI 10.1111/j.1601-0825.2007.01425.xDeshpande, K., Jain, A., Sharma, R., Prashar, S., Jain, R., Diabetes and periodontitis (2010) J Indian Soc Periodontol, 14, pp. 207-212Darnell, J.A., Saunders, M.J., Oral manifestations of the diabetic patient (1990) Tex Dent J, 107, pp. 23-27Lamey, P.J., Darwazeh, A.M., Frier, B.M., Oral disorders associated with diabetes mellitus (1992) Diabet Med, 9, pp. 410-416George, K., Zafiropoulos, G.G., Murat, Y., Hubertus, S., Nisengard, R.J., Clinical and microbiological status of osseointegrated implants (1994) J Periodontol, 65, pp. 766-770Knoernschild, K.L., Bacon, W.L., Fischman, G.S., Campbell, S.D., Effect of pH on endotoxin affinity for metal-ceramic alloys (2001) Journal of Prosthetic Dentistry, 86 (6), pp. 644-649. , DOI 10.1067/mpr.2001.120842Knoernschild, K.L., Tompkins, G.R., Lefebvre, C.A., Griffiths, L.L., Schuster, G.S., Effect of pH on Porphyromonas gingivalis endotoxin affinity for resins (1996) International Journal of Prosthodontics, 9 (3), pp. 239-247Nelson, K.E., Fleischmann, R.D., DeBoy, R.T., Paulsen, I.T., Fouts, D.E., Eisen, J.A., Daugherty, S.C., Fraser, C.M., Complete genome sequence of the oral pathogenic bacterium Porphyromonas gingivalis strain W83 (2003) Journal of Bacteriology, 185 (18), pp. 5591-5601. , DOI 10.1128/JB.185.18.5591-5601.2003Robinson, F.G., Knoernschild, K.L., Sterrett, J.D., Tompkins, G.R., Porphyromonas gingivalis endotoxin affinity for dental ceramics (1996) Journal of Prosthetic Dentistry, 75 (2), pp. 217-227Cortada, M., Giner, L.L., Costa, S., Gil, F.J., Rodriguez, D., Planell, J.A., Galvanic corrosion behavior of titanium implants coupled to dental alloys (2000) Journal of Materials Science: Materials in Medicine, 11 (5), pp. 287-293. , DOI 10.1023/A:1008905229522Vieira, A.C., Ribeiro, A.R., Rocha, L.A., Celis, J.P., Influence of pH and corrosion inhibitors on the tribocorrosion of titanium in artificial saliva (2006) Wear, 261 (9), pp. 994-1001. , DOI 10.1016/j.wear.2006.03.031, PII S004316480600113X, TribocorrosionNikolopoulou, F., Saliva and dental implants (2006) Implant Dent, 15, pp. 372-376Chaturvedi, T.P., An overview of the corrosion aspect of dental implants (titanium and its alloys) (2009) Indian J Dent Res, 20, pp. 91-98Correa, C.B., Pires, J.R., Fernandes-Filho, R.B., Sartori, R., Vaz, L.G., Fatigue and fluoride corrosion on Streptococcus mutans adherence to titanium-based implant/component surfaces (2009) J Prosthodont, 18, pp. 382-387Messer, R.L., Seta, F., Mickalonis, J., Brown, Y., Lewis, J.B., Corrosion of phosphate-enriched titanium oxide surface dental implants (TiUnite) under in vitro inflammatory and hyperglycemic conditions (2010) J Biomed Mater Res B Appl Biomater, 92, pp. 525-534Messer, R.L., Tackas, G., Mickalonis, J., Brown, Y., Lewis, J.B., Corrosion of machined titanium dental implants under inflammatory conditions (2009) J Biomed Mater Res B Appl Biomater, 88, pp. 474-481Barao, V.A., Mathew, M.T., Assuncao, W.G., Yuan, J.C., Wimmer, M.A., The role of lipopolysaccharide on the electrochemical behavior of titanium (2011) J Dent Res, 90, pp. 613-618Gittens, R.A., Olivares-Navarrete, R., Tannenbaum, R., Boyan, B.D., Schwartz, Z., Electrical implications of corrosion for osseointegration of titanium implants (2011) J Dent Res, 90, pp. 1389-1397Barao, V.A., Mathew, M.T., Assuncao, W.G., Yuan, J.C., Wimmer, M.A., Stability of cp-Ti and Ti-6Al-4V alloy for dental implants as a function of saliva pH - An electrochemical study (2012) Clin Oral Implants Res, 23, pp. 1055-1062Zhoua, L.Y., Mitsuo, N., Toshikazu, A., Hisao, F., Todaa, H., Corrosion resistance and biocompatibility of Ti-Ta alloys for biomedical applications (2007) Materials, 48, pp. 380-384Oliveira, N.T., Guastaldi, A.C., Electrochemical stability and corrosion resistance of Ti-Mo alloys for biomedical applications (2009) Acta Biomater, 5, pp. 399-405Mareci, D., Chelariu, R., Gordin, D.M., Ungureanu, G., Gloriant, T., Comparative corrosion study of Ti-Ta alloys for dental applications (2009) Acta Biomater, 5, pp. 3625-3639Olmedo, D.G., Paparella, M.L., Brandizzi, D., Cabrini, R.L., Reactive lesions of peri-implant mucosa associated with titanium dental implants: A report of 2 cases (2010) Int J Oral Maxillofac Surg, 39, pp. 503-507Olmedo, D.G., Paparella, M.L., Spielberg, M., Brandizzi, D., Guglielmotti, M.B., Oral mucosa tissue response to titanium cover screws (2012) J Periodontol, 83, pp. 973-980Trisi, P., Lazzara, R., Rebaudi, A., Rao, W., Testori, T., Porter, S.S., Bone-implant contact on machined and dual acid-etched surfaces after 2 months of healing in the human maxilla (2003) Journal of Periodontology, 74 (7), pp. 945-956. , DOI 10.1902/jop.2003.74.7.945Xavier, S.P., Carvalho, P.S.P., Beloti, M.M., Rosa, A.L., Response of rat bone marrow cells to commercially pure titanium submitted to different surface treatments (2003) Journal of Dentistry, 31 (3), pp. 173-180. , DOI 10.1016/S0300-5712(03)00027-7Buser, D., Broggini, N., Wieland, M., Schenk, R.K., Denzer, A.J., Cochran, D.L., Hoffmann, B., Steinemann, S.G., Enhanced bone apposition to a chemically modified SLA titanium surface (2004) Journal of Dental Research, 83 (7), pp. 529-533Tavares, M.G., De Oliveira, P.T., Nanci, A., Hawthorne, A.C., Rosa, A.L., Treatment of a commercial, machined surface titanium implant with H 2SO4/H2O2 enhances contact osteogenesis (2007) Clin Oral Implants Res, 18, pp. 452-458Pai, P.S., Mathew, M.T., Stack, M.M., Rocha, L.A., Some thoughts on neural network modelling of microabrasion-corrosion processes (2008) Tribology International, 41, pp. 672-681Lin, A., Wang, C.J., Kelly, J., Gubbi, P., Nishimura, I., The role of titanium implant surface modification with hydroxyapatite nanoparticles in progressive early bone-implant fixation in vivo (2009) Int J Oral Maxillofac Implants, 24, pp. 808-816Wennerberg, A., Albrektsson, T., Effects of titanium surface topography on bone integration: A systematic review (2009) Clin Oral Implants Res, 20 (SUPPL. 4), pp. 172-184Gotfredsen, K., Berglundh, T., Lindhe, J., Bone reactions adjacent to titanium implants subjected to static load of different duration. A study in the dog (III) (2001) Clinical Oral Implants Research, 12 (6), pp. 552-558Klokkevold, P.R., Han, T.J., How do smoking, diabetes, and periodontitis affect outcomes of implant treatment? (2007) Int J Oral Maxillofac Implants, 22 (SUPPL.), pp. 173-202Tawil, G., Younan, R., Azar, P., Sleilati, G., Conventional and advanced implant treatment in the type II diabetic patient: Surgical protocol and long-term clinical results (2008) Int J Oral Maxillofac Implants, 23, pp. 744-752Tamam, E., Turkyilmaz, I., Effects of pH and elevated glucose levels on the electrochemical behaviour of dental implants (2012) J Oral Implantol, , http://dx.doi.org/10.1563/AAID-JOI-D-11-00083.1, In-Press. doiMathew, M.T., Barao, V.A., Yuan, J.C., Assuncao, W.G., Sukotjo, C., What is the role of lipopolysaccharide on the tribocorrosive behavior of titanium? (2012) J Mech Behav Biomed Mater, 8, pp. 71-85Barao, V.A., Mathew, M.T., Yuan, J.C., Knoernschild, K.L., Assuncao, W.G., Influence of corrosion on lipopolysaccharide affinity for two different titanium materials (2013) J Prosthet Dent, 110, pp. 462-470Abe, Y., Kokubo, T., Yamamuro, T., Apatite coating on ceramics, metals and polymers utilizing a biological process (1990) Journal of Materials Science: Materials in Medicine, 1 (4), pp. 233-238Zhang, S.M., Qiu, J., Tian, F., Guo, X.K., Zhang, F.Q., Corrosion behavior of pure titanium in the presence of Actinomyces naeslundii (2013) J Mater Sci Mater Med, 24, pp. 1229-1237Faverani, L.P., Barao, V.A., Ramalho-Ferreira, G., Ferreira, M.B., Garcia-Junior, I.R., Effect of bleaching agents and soft drink on titanium surface topography (2014) J Biomed Mater Res B Appl Biomater, 102, pp. 22-30Al Jabbari, Y., Fournelle, R., Ziebert, G., Toth, J., Iacopino, A., Mechanical behavior and failure analysis of prosthetic retaining screws after long-term use in vivo. Part 2: Metallurgical and microhardness analysis (2008) J Prosthodont, 17, pp. 181-191Assuncao, W.G., Jorge, J.R., Dos Santos, P.H., Barao, V.A., Gomes, E.A., The effect of mechanical cycling and different misfit levels on Vicker's [sic] microhardness of retention screws for single implant-supported prostheses (2011) J Prosthodont, 20, pp. 523-527Bundy, K.J., Corrosion and other electrochemical aspects of biomaterials (1994) Crit Rev Biomed Eng, 22, pp. 139-251Mabilleau, G., Bourdon, S., Joly-Guillou, M.L., Filmon, R., Basle, M.F., Chappard, D., Influence of fluoride, hydrogen peroxide and lactic acid on the corrosion resistance of commercially pure titanium (2006) Acta Biomaterialia, 2 (1), pp. 121-129. , DOI 10.1016/j.actbio.2005.09.004, PII S1742706105001315Morgan, T.D., Wilson, M., The effects of surface roughness and type of denture acrylic on biofilm formation by Streptococcus oralis in a constant depth film fermentor (2001) Journal of Applied Microbiology, 91 (1), pp. 47-53. , DOI 10.1046/j.1365-2672.2001.01338.xBarao, V.A., Yoon, C.J., Mathew, M.T., Yuan, J.C., Wu, C.D., Attachment of Porphyromonas gingivalis to corroded commercially pure titanium and titanium-aluminum-vanadium alloy (2014) J Periodontol, , in pressBollen, C.M.L., Papaioanno, W., Van Eldere, J., Schepers, E., Quirynen, M., Van Steenberghe, D., The influence of abutment surface roughness on plaque accumulation and peri-implant mucositis (1996) Clinical Oral Implants Research, 7 (3), pp. 201-211Yang, C.H., Wang, Y.T., Tsai, W.F., Ai, C.F., Lin, M.C., Effect of oxygen plasma immersion ion implantation treatment on corrosion resistance and cell adhesion of titanium surface (2011) Clin Oral Implants Res, 22, pp. 1426-1432Li, J.L., Sun, M.R., Ma, X.X., Tang, G.Z., Structure and tribological performance of modified layer on Ti6Al4V alloy by plasma-based ion implantation with oxygen (2006) Wear, 261, pp. 1247-1252Affronti, J., Chronic pancreatitis and exocrine insufficiency (2011) Prim Care, 38, pp. 515-537+ixLi, B., Luo, C., Chowdhury, S., Gao, Z.H., Liu, J.L., Parp1 deficient mice are protected from streptozotocin-induced diabetes but not caerulein-induced pancreatitis, independent of the induction of Reg family genes (2013) Regul Pept, 186 C, pp. 83-91Hwang, A.L., Haynes, K., Hwang, W.T., Yang, Y.X., Metformin and survival in pancreatic cancer: A retrospective cohort study (2013) Pancreas, 42, pp. 1054-1059Savari, O., Zielinski, M.C., Wang, X., Misawa, R., Millis, J.M., Distinct function of the head region of human pancreas in the pathogenesis of diabetes (2013) Islets, 5, pp. 226-228Baker, P., Fain, P., Kahles, H., Yu, L., Hutton, J., Genetic determinants of 21-hydroxylase autoantibodies amongst patients of the Type 1 Diabetes Genetics Consortium (2012) J Clin Endocrinol Metab, 97, pp. E1573-E1578Colucci, R., Jimenez, R.E., Farrar, W., Malgor, R., Kohn, L., Coexistence of Cushing syndrome from functional adrenal adenoma and Addison disease from immune-mediated adrenalitis (2012) J Am Osteopath Assoc, 112, pp. 374-379Meyer, G., Hackemann, A., Penna-Martinez, M., Badenhoop, K., What affects the quality of life in autoimmune Addison's disease? (2013) Horm Metab Res, 45, pp. 92-95Tada, S., Stegaroiu, R., Kitamura, E., Miyakawa, O., Kusakari, H., Influence of implant design and bone quality on stress/strain distribution in bone around implants: A 3-dimensional finite element analysis (2003) International Journal of Oral and Maxillofacial Implants, 18 (3), pp. 357-368Winter, W., Klein, D., Karl, M., Effect of model parameters on finite element analysis of micromotions in implant dentistry (2013) J Oral Implantol, 39, pp. 23-2