4,582 research outputs found

    Towards durable multistakeholder-generated solutions: The pilot application of a problem-oriented policy learning protocol to legality verification and community rights in Peru

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    This paper reports and reflects on the pilot application of an 11-step policy learning protocol that was developed by Cashore and Lupberger (2015) based on several years of Cashore’s multi-author collaborations. The protocol was applied for the first time in Peru in 2015 and 2016 by the IUFRO Working Party on Forest Policy Learning Architectures (hereinafter referred to as the project team). The protocol integrates insights from policy learning scholarship (Hall 1993, Sabatier 1999) with Bernstein and Cashore’s (2000, 2012) four pathways of influence framework. The pilot implementation in Peru focused on how global timber legality verification interventions might be harnessed to promote local land rights. Legality verification focuses attention on the checking and auditing of forest management units in order to verify that timber is harvested and traded in compliance with the law. We specifically asked: How can community legal ownership of, and access to, forestland and forest resources be enhanced? The protocol was designed as a dynamic tool, the implementation of which fosters iterative rather than linear processes. It directly integrated two objectives: 1) identifying the causal processes through which global governance initiatives might be harnessed to produce durable results ‘on the ground’; 2) generating insights and strategies in collaboration with relevant stakeholders. This paper reviews and critically evaluates our work in designing and piloting the protocol. We assess what seemed to work well and suggest modifications, including an original diagnostic framework for nurturing durable change. We also assess the implications of the pilot application of the protocol for policy implementation that works to enhance the influence of existing international policy instruments, rather than contributing to fragmentation and incoherence by creating new ones

    pPKCα mediated-HIF-1α activation related to the morphological modifications occurring in neonatal myocardial tissue in response to severe and mild hyperoxia

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    In premature babies birth an high oxygen level exposure can occur and newborn hyperoxia exposure can be associated with free radical oxygen release with impairment of myocardial function, while in adult animal models short exposure to hyperoxia seems to protect heart against ischemic injury. Thus, the mechanisms and consequences which take place after hyperoxia exposure are different and related to animals age. The aim of our work has been to analyze the role played by HIF-1α in the occurrence of the morphological modifications upon hyperoxia exposure in neonatal rat heart. Hyperoxia exposure induces connective compartment increase which seems to allow enhanced blood vessels growth. An increased hypoxia inducible factor-1α (HIF-1α) translocation and vascular endothelial growth factor (VEGF) expression has been found upon 95% oxygen exposure to induce morphological modifications. Upstream pPKC-α expression increase in newborn rats exposed to 95% oxygen can suggest PKC involvement in HIF-1α activation. Since nitric oxide synthase (NOS) are involved in heart vascular regulation, endothelial NOS (e-NOS) and inducible NOS (i-NOS) expression has been investigated: a lower eNOS and an higher iNOS expression has been found in newborn rats exposed to 95% oxygen related to the evidence that hyperoxia provokes a systemic vasoconstriction and to the iNOS pro-apoptotic action, respectively. The occurrence of apoptotic events, evaluated by TUNEL and Bax expression analyses, seems more evident in sample exposed to severe hyperoxia. All in all such results suggest that in newborn rats hyperoxia can trigger oxygen free radical mediated membrane injury through a pPKCα mediated HIF-1α signalling system, even though specificity of such response could be obtained by in vivo administration to the rats of specific inhibitors of PKCα. This intracellular signalling can switch molecular events leading to blood vessels development in parallel to pro-apoptotic events due to an immature anti-oxidant defensive system in newborn rat hearts

    Nature-Inspired Interconnects for Self-Assembled Large-Scale Network-on-Chip Designs

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    Future nano-scale electronics built up from an Avogadro number of components needs efficient, highly scalable, and robust means of communication in order to be competitive with traditional silicon approaches. In recent years, the Networks-on-Chip (NoC) paradigm emerged as a promising solution to interconnect challenges in silicon-based electronics. Current NoC architectures are either highly regular or fully customized, both of which represent implausible assumptions for emerging bottom-up self-assembled molecular electronics that are generally assumed to have a high degree of irregularity and imperfection. Here, we pragmatically and experimentally investigate important design trade-offs and properties of an irregular, abstract, yet physically plausible 3D small-world interconnect fabric that is inspired by modern network-on-chip paradigms. We vary the framework's key parameters, such as the connectivity, the number of switch nodes, the distribution of long- versus short-range connections, and measure the network's relevant communication characteristics. We further explore the robustness against link failures and the ability and efficiency to solve a simple toy problem, the synchronization task. The results confirm that (1) computation in irregular assemblies is a promising and disruptive computing paradigm for self-assembled nano-scale electronics and (2) that 3D small-world interconnect fabrics with a power-law decaying distribution of shortcut lengths are physically plausible and have major advantages over local 2D and 3D regular topologies

    The effect of electronic energy loss on the dynamics of thermal spikes in Cu

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    We present results of a molecular dynamics simulation study of the effect of electron-ion interactions on the dynamics of the thermal spike in Cu. Interatomic forces are described with a modified embedded atom method potential. We show that the electron-ion interaction acts to reduce the lifetime of the thermal spike and therefore the amount of atomic rearrangement that takes place in energetic displacement cascades in Cu. The results point toward the important effect that inelastic energy losses might have on the dynamics of displacement cascades in the subcascade energy regime where the lifetime of the thermal spike is expected to exceed the electron-phonon coupling tim

    Theory of Room Temperature Ferromagnet V(TCNE)_x (1.5 < x < 2): Role of Hidden Flat Bands

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    Theoretical studies on the possible origin of room temperature ferromagnetism (ferromagnetic once crystallized) in the molecular transition metal complex, V(TCNE)_x (1.5<x<2) have been carried out. For this family, there have been no definite understanding of crystal structure so far because of sample quality, though the effective valence of V is known to be close to +2. Proposing a new crystal structure for the stoichiometric case of x=2, where the valence of each TCNE molecule is -1 and resistivity shows insulating behavior, exchange interaction among d-electrons on adjacent V atoms has been estimated based on the cluster with 3 vanadium atoms and one TCNE molecule. It turns out that Hund's coupling among d orbitals within the same V atoms and antiferromagnetic coupling between d oribitals and LUMO of TCNE (bridging V atoms) due to hybridization result in overall ferromagnetism (to be precise, ferrimagnetism). This view based on localized electrons is supplemented by the band picture, which indicates the existence of a flat band expected to lead to ferromagnetism as well consistent with the localized view. The off-stoichiometric cases (x<2), which still show ferromagnetism but semiconducting transport properties, have been analyzed as due to Anderson localization.Comment: Accepted for publication in J. Phys. Soc. Jpn. Vol.79 (2010), No. 3 (March issue), in press; 6 pages, 8 figure

    A Full-Field Calibration Approach on Material Parameter Identification

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    In the recent years, the usage of HS-steels has risen significantly in the automotive field. Their characteristics, such as hardness and favorable weight to strength ratio, can increase safety, fuel efficiency and overall product profitability. In this context, for the design with this material it has become crucial to be able to characterize precisely HS-steels and accurately predict their failure in many complex conditions, to fully exploit their capabilities. One of the most accredited ways to approach the prediction of failure for a wide range of materials is the generalized incremental stress-state dependent damage model GISSMO. The model is highly flexible and provides a framework inside LS-DYNA in which failure parameters can be tuned to reproduce experimental data. The definition of the optimal parameters is an inverse problem, therefore it was implemented using LS-OPT. In this work, the experimental evaluation of the MS1500 was carried out using the digital image correlation (DIC). With such technology, the displacements’ field of the test specimen is recorded.The evalueted field was processed as a family of stress-strain curves (hyper-curves) and became the objective of the optimization. This approach is named full field calibration and in this work was split in two phases. First, the stress-strain curve of the material was defined, then the tuning of the GISSMO parameters was performed. To evaluate the effectiveness of the full field approach a parallel study was implemented. The same routine of optimization run with a single stress-strain curve, which was measured with an extensometer. The comparison between the results obtained with the traditional approach and the results obtained with the full field approach highlighted the strenghts and the limitations of the two methods

    Operational Framework to Quantify “Quality of Recycling” across Different Material Types

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    Many pledges and laws are setting recycling targets without clearly defining quality of recycling. Striving to close this gap, this study presents an operational framework to quantify quality of recycling. The framework comprises three dimensions: the Virgin Displacement Potential (VDP); In-Use Stocks Lifetime (IUSL); and Environmental Impact (EI). The VDP indicates to what extent a secondary material can be used as a substitute for virgin material; the IUSL indicates how much of a certain material is still functional in society over a given time frame, and the EI is a measure of the environmental impact of a recycling process. The three dimensions are aggregated by plotting them in a distance-to-target graph. Two example calculations are included on poly(ethylene terephthalate) (PET) and glass. The results indicate that the recycling of bottle and container glass collected via a deposit-refund system has the lowest distance-to-target, at 1.05, and, thus, the highest quality of recycling. For PET bottles, the highest quality of recycling is achieved in closed-loop mechanical recycling of bottles (distance to optimal quality of 0.96). Furthermore, sensitivity analysis indicates that certain parameters, e.g., the collection rate for PET bottles, can reduce the distance-to-target to 0.75 when all bottles are collected for recycling

    Pre-surgery supportive and goal-oriented strategies are associated with lower post-surgery perceived distress in women diagnosed with breast cancer

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    Background: Psycho-oncology literature pointed out that individual health outcomes may depend on patients’ propensity to adopt approach or, conversely, avoidant coping strategies. Nevertheless, coping factors associated with postoperative distress remain unclear, unfolding the lack of tailored procedures to help breast cancer patients manage the psychological burden of scheduled surgery. In view of this, the present study aimed at investigating: 1. pre-/post-surgery distress variations occurring among women diagnosed with breast cancer; 2. the predictivity of approach and avoidant coping strategies and factors in affecting post-surgery perceived distress. Methods: N = 150 patients (mean age = 59.37; SD = ± 13.23) scheduled for breast cancer surgery were administered a screening protocol consisting of the Distress Thermometer (DT) and the Brief-COPE. The DT was used to monitor patients’ distress levels before and after surgery (± 7&nbsp;days), whereas the Brief-COPE was adopted only preoperatively to evaluate patients’ coping responses to the forthcoming surgical intervention. Non-parametric tests allowed for the detection of pre-/post-surgery variations in patients’ perceived distress. Factor analysis involved the extraction and rotation of principal components derived from the Brief-COPE strategies. The predictivity of such coping factors was investigated through multiple regression (Backward Elimination). Results: The Wilcoxon Signed-Rank Test yielded a significant variation in DT mean scores (TW = -5,68 &lt; -zα/2 = -1,96; p &lt;.001) indicative of lower perceived distress following surgery. The four coping factors extracted and Varimax-rotated were, respectively: 1. cognitive processing (i.e., planning + acceptance + active coping + positive reframing); 2. support provision (i.e., instrumental + emotional support); 3. emotion-oriented detachment (i.e., self-blame + behavioral disengagement + humor + denial); 4. goal-oriented detachment (i.e., self-distraction). Among these factors, support provision (B =.458; β = −.174; t = − 2.03; p =.045), encompassing two approach coping strategies, and goal-oriented detachment (B =.446; β = −.176; t = − 2.06; p =.042), consisting of one avoidant strategy, were strongly related to post-surgery distress reduction. Conclusion: The present investigation revealed that the pre-surgery adoption of supportive and goal-oriented strategies led to postoperative distress reduction among breast cancer patients. These findings highlight the importance of timely psychosocial screening and proactive interventions in order to improve patients’ recovery and prognosis

    Multiparametric seafloor exploration: the Marsili Basin and Volcanic Seamount case (Tyrrhenian Sea, Italy)

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    Exploration of ocean seafloor is of paramount importance for a better understanding of the geodynamic evolution of our Planet. The pilot experiment of ORION-GEOSTAR 3 EC project was the first long-term continuous geophysical and oceanographic experiment of an important seafloor area of Southern Tyrrhenian Sea, the Marsili abyssal plain. The latter hosts the Marsili Seamount which is Europe’s one of the largest underwater volcano of Plio-Pleistocenic age. In spite of its dimensions, it is rather unknown about the present characteristics and activity. For this reason, we deployed a deep-sea observatory network, composed by two bottom observatories, on the seafloor at the base of the seamount at 3320 m b.s.l., in the period December 2003-May 2005. Some of the instruments on board the observatory were: broad-band seismometers, hydrophones, gravity meter, two magnetometers (scalar and vectorial), 3D single-point current meter, ADCP, CTD, automatic pH analyser and off-line water sampler for laboratory analyses. The first successful scientific objective was to obtain long-term continuous recordings under a unique time reference. The data analysis shows that they are generally of good quality and really continuous (only a few gaps). As a first step we performed a classification of seismic waveforms, a first inversion of magnetic variational data, and a first analysis of gravity meter, chemical and oceanographic data. Analysis of individual time series has shown interesting results, i.e. depth of the magnetic Moho under the Marsili, attenuation of recorded seismic body waves and clues of hydrothermal circulation. We show examples of the preliminary data analysis together with first results and comparisons among data coming from different sensors.PublishedCambridge, UK, February 24-26, 20091.8. Osservazioni di geofisica ambientale3.8. Geofisica per l'ambienteope
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