Censorship and autocensorship: Some considerations on the editorial history of the Parhaego

In this article, we have examined some aspects of the editing of the Parhaego (Reflections on Parhae). First of all, we have tried to contextualize the work within the panorama of late Chosŏn historiography. In this sense, we have remarked that the work is part of a gradual reshaping of the story of Parhae, rearticulated within the narrative of Chosŏn history. Yu Tŭkkong’s major contribution was not to revolutionize the historical narrative of Korea nor the perception of the Parhae kingdom, but rather to collect all the sources then available for reconstructing the history of the kingdom, enjoying his privileged position within the Kyujanggak (the Royal Library). In considering this, we have observed that despite the apparent liberalism of the Chŏngjo reign, publishing and scholarship were actually under strict surveillance. During this period, the king imposed a ban on the import of books from the Qing Empire and also forced several scholars to correct their literary style. Amid this climate of control and censorship, the editing of the Parhaego took place－a work that had a rather unusual and troubled genesis, being subjected to numerous alterations and corrections since its publication in 1784. Reconstructing the genesis of this book, albeit only partially, may also provide a starting point for further reflections on authorship during this crucial phase of the Chosŏn period, when the book was exposed to possible corrections, rewritings, and expansions, even without the full consent of the original author. This process is particularly evident in the Parhaego, which was not merely historical work, but also highly political as a manifesto giving voice to the policy of reconquering the Northern Territories that was in vogue in those years

Introduzione alla scrittura giapponese

Introduzione all'apprendimento della scrittura giapponese con esercizi e note esplicative

Risk of COVID-19 in-hospital mortality in people living with HIV compared to general population according to age and CD4 strata: data from the ICONA network

OBJECTIVES: We aimed to study whether people living with HIV (PLWH) are at higher risk of in-hospital COVID-19 mortality compared to the general population (GenPop). METHODS: This was a retrospective study in 19 Italian centers (February 2020 to November 2022) including hospitalized PLWH and GenPop with SARS-CoV-2 infection. The main outcome was in-hospital mortality. Competing risk analyses by Fine-Gray regression model were used to estimate the association between in-hospital mortality and HIV status/age. RESULTS: A total of 7399 patients with COVID-19 were included, 239 (3.2%) PLWH, and 7160 (96.8%) GenPop. By day 40, in-hospital death occurred in 1283/7160 (17.9%) among GenPop and 34/239 (14.2%) among PLWH. After adjusting for potential confounders, compared to GenPop 350 (aSHR 1.11 [95% CI 0.41-2.99]). CONCLUSIONS: In PLWH aged <65 years a CD4 ≤350 rather than HIV itself seems the driver for the observed higher risk of in-hospital mortality. We cannot however rule out that HIV infection per se is the risk factor in those aged ≥65 years

The Heterogeneity of Skewness in T2W-Based Radiomics Predicts the Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer

Our study aimed to investigate whether radiomics on MRI sequences can differentiate responder (R) and non-responder (NR) patients based on the tumour regression grade (TRG) assigned after surgical resection in locally advanced rectal cancer (LARC) treated with neoadjuvant chemoradiotherapy (nCRT). Eighty-five patients undergoing primary staging with MRI were retrospectively evaluated, and 40 patients were finally selected. The ROIs were manually outlined in the tumour site on T2w sequences in the oblique-axial plane. Based on the TRG, patients were grouped as having either a complete or a partial response (TRG = (0,1), n = 15). NR patients had a minimal or poor nCRT response (TRG = (2,3), n = 25). Eighty-four local first-order radiomic features (RFs) were extracted from tumour ROIs. Only single RFs were investigated. Each feature was selected using univariate analysis guided by a one-tailed Wilcoxon rank-sum. ROC curve analysis was performed, using AUC computation and the Youden index (YI) for sensitivity and specificity. The RF measuring the heterogeneity of local skewness of T2w values from tumour ROIs differentiated Rs and NRs with a p-value ≈ 10−5; AUC = 0.90 (95%CI, 0.73–0.96); and YI = 0.68, corresponding to 80% sensitivity and 88% specificity. In conclusion, higher heterogeneity in skewness maps of the baseline tumour correlated with a greater benefit from nCR

Lingua coreana 3

Grammatica di coreano, livello intermedi