H.E.A.R.T.

Healthy parenting and family resilience in early childhood has been shown to be an important factor in building emotional resilience for the children: it illustrates that when parents have higher emotional resilience, their children tend to have higher emotional resilience as well. However, the tools that available in the market right now only teach people what emotional resilience rather than how to practice it in daily life. This report describes our project to create a virtual reality tool that can not only teach the importance of emotional resilience, but also help the parents develop personal resilience. The system is based on the VR Empathy Training Tool created by a former senior design project in which the user can interact with a crying child and learn how to handle stress under certain circumstances. The new system will add new features so that it can inform users about their stress level and allow the users to track their progress

GPU acceleration of time-domain fluorescence lifetime imaging

Fluorescence lifetime imaging microscopy (FLIM) plays a significant role in biological sciences, chemistry, and medical research. We propose a Graphic Processing Units (GPUs) based FLIM analysis tool suitable for high-speed and flexible time-domain FLIM applications. With a large number of parallel processors, GPUs can significantly speed up lifetime calculations compared to CPU-OpenMP (parallel computing with multiple CPU cores) based analysis. We demonstrate how to implement and optimize FLIM algorithms on GPUs for both iterative and non-iterative FLIM analysis algorithms. The implemented algorithms have been tested on both synthesized and experimental FLIM data. The results show that at the same precision the GPU analysis can be up to 24-fold faster than its CPU-OpenMP counterpart. This means that even for high precision but time-consuming iterative FLIM algorithms, GPUs enable fast or even real-time analysis

An audit of dressing practice by occupational therapists in acute stroke settings in England

Introduction Dressing independence is commonly affected after stroke, with clinical guidelines recommending that dressing practice should routinely be provided for those with dressing difficulties. The aim of this study was to update the literature on current practice in the treatment of dressing problems in stroke rehabilitation units. Method A questionnaire survey of occupational therapists experienced in stroke care was sent to 157 stroke units in England. Results Responses were received from 70 stroke units. Frequency and duration of dressing practice varied substantially between units, with respondents typically providing dressing practice for six to 10 patients per week and spending 30 to 45 minutes per treatment session. Only 17 respondents (24.3%) stated that they regularly used standardised assessments of dressing ability. The functional approach was used more widely than the remedial approach. Service priorities, working environment and limitations of time and staffing were reported to influence dressing practice. Conclusion There is widespread variability in dressing practice. There is a lack of use of standardised dressing assessments, and therapists’ rationale for their choice of approach is unclear

Two-photon imaging and photothermal therapy of cancer cells using biofunctional gold nanorods

Transferrin-conjugated gold nanorods were used for targeting, two-photon imaging and photothermal therapy of cancer cells. The presence of nanorods significantly reduced the laser power effective for therapy.<br /

Numerical simulation of exploring fish motion by a series of linked rigid bodies

Propulsion and manoeuvring ability are parts of the most common and complicated mechanisms in nature, such as fish swimming in the water and birds flying in the sky. In order to get a deep understanding of these problems, a comprehensive and completed replication of fish movements is carried out in this project. Present work is based on a robotic fish named Amphibot III, which is a bio-inspired swimming robot. It is composed of 8 elements and the last part has a caudal fin attached as a tail. By using CFD method, the caudal fin is omitted in order to simplify the model. These elements in the model are connected by hinges. Commercial software FLUENT is used to solve flow field. Swimming tests are performed under two different conditions by varying the frequency and amplitude of the angular motion at the hinges. The motion curve at the head of fish is presented under both conditions

Estimating fluorescence lifetimes using the expectation-maximisation algorithm

The expectation-maximisation (EM) algorithm uses incomplete data to get the estimation of the probabilistic model parameter, and it has been widely used in machine learning. EM techniques are applied to estimate fluorescence lifetimes in time-correlated single-photon counting based fluorescence lifetime imaging experiments without measuring the instrument response functions. The results of Monte Carlo simulations indicate that the proposed approach can obtain better or comparable accuracy and precision performances than the previously reported method

Effective elastic properties of randomly distributed void models for porous materials

This is the post-print version of the final paper published in International Journal of Mechanical Sciences. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. Copyright @ 2010 Elsevier B.V.Many 2D analytical models are available for estimating the effective elastic properties of porous materials. Most of these models adopt circular voids of a uniform diameter in superlattice arrays, such as unit void or periodically positioned models. There are two principal issues in a realistic representation of porous materials: the random distribution of a statistically sufficiently large number of voids in the model, and the random distribution of the size and position of the voids. Numerical schemes such as the FEM or the BEM have also been presented to cater for regular patterned circular voids. However, due to the large number of elements needed to produce sufficient accuracy for the curved boundary of circular voids or modelling a statistically sufficient number of voids with a random distribution in both the void size and the position, no such model has yet been produced. Modelling based on an FEM approach using a simplified approximation for void geometry is proposed here for the calculation of the effective elastic properties of porous solids. A plane strain model of a square geometry is adopted for a 2D array of voids. This simplified square shape allows a large number of voids to be simulated with a random distribution for both void sizes and their locations. The problem of anisotropy, which arises from the square shape, is discussed. It is verified that along the two principal directions (parallel to the sides of the square voids), the elastic properties remain the same as those predicted by using a circular void geometry. This square-shaped approximation, with its reduced requirement for FE analysis, has the potential to be extended to 3-dimensional modelling for a realistic simulation of engineering materials.University of Aberdee

Fluorescence lifetime estimation method for incomplete decay

A new incomplete decay signal model is proposed to describe the incomplete decay effects in a time- correlated single-photon counting (TCSPC) based fluorescence lifetime imaging (FLIM) system. Based on this model, we modified a MUltiple SIgnal Classification (MUSIC) algorithm to eliminate the incomplete decay effects. Monte Carlo simulations were carried out to demonstrate the performances of the proposed approach. Simulations show that the proposed method is insensitive to the laser pulse rate and has a larger lifetime dynamic range compared with previously reported approaches. As far as we know, this new method is the first non-fitting method that can resolve incomplete decay effects for multi-exponential decays

Towards Establishing Effective Protective Boundaries for the Lunan Stone Forest Using an Online Spatial Decision Support System

 The Lunan Stone Forest is the Worldʼs premier pinnacle karst landscape, and was established as a national park in 1982. The existing boundaries are essentially arbitrary, based on notional scenic value, and take into consideration neither the physical landscape nor the existing pattern of urban development. Moreover, the location of the boundaries is not clear to the local community, rendering them largely ineffective. Developing an online Spatial Decision Support System (SDSS) potentially provides a way to establish protective boundaries that are meaningful from the perspective of karst science, yet also readily identifiable by the local community within the context of the existing urban fabric. The 7km2 “core area” of the Stone Forest Park is used to illustrate the use of the SDSS.   Lunanski kaniti gozd je najlepši primer »kamnitega gozda« (shilin) na svetu in je bil 1982 razglašen za narodni park. Sedanje meje parka so bile dogovorjene na osnovi zaznavne pokrajinske vrednote in ne upoštevajo niti fizičnih lastnosti pokrajine niti obstoječega vzorca razvoja mesta. Še več, lokalnim skupnostim meje niso jasne in so zato še manj učinkovite. Z razvojem Spatial Decision Support System (SDSS) na spletu je dano orodje, s pomočjo katerega bi bilo mogoče določiti meje varovanega območja, ki bi bile zadovoljujoče z vidika krasoslovja in sprejete s strani lokalnih skupnosti v skladu s sedanjim urbanim razvojem. Na 7 km2 osrednjega dela Kamnitega gozda je prikazana možnost uporabe SDSS.

Design of a compact microfludic device for controllable cell distribution

A compact microfluidic device with 96 microchambers allocated within four circular units was designed and examined for cell distribution. In each unit, cells were distributed to the surrounding chambers radially from the center. The circular arrangement of the chambers makes the design simple and compact. A controllable and quantitative cell distribution is achievable in this device. This design is significant to the microfluidic applications where controllable distribution of cells in multipule microchambers is demanded.<br /