Views from the Ohio manufacturing index

An introduction to the experimental Ohio Manufacturing Index and a brief examination of the recent patterns of manufacturing growth occurring in the state.Manufactures - Ohio ; Ohio ; Economic indicators - Ohio

Calibration of a fission gas monitor

Calibration of argon gas neutron activation sampling devic

Evaluating the role of citizen science in biological investigations

Considering recent and predicted ecological changes (caused by global climate change), baseline monitoring of biological diversity becomes an extremely useful record to have. Citizen science provides a unique, low-cost, high output method of attaining large data sets which has already been implemented in several studies. They are used by major bodies such as the Natural History Museum, OPAL and the RSPB. Despite this concerns lie with the accuracy of the data – can volunteers really produce real data? In this study various aspects were investigated, firstly the current public opinion about citizen science, how we can train volunteers carrying out surveys, and the kinds of method suitable for biological monitoring by citizen scientists. This report finds a generally good level of public literacy in terms of the existence and the potential of, citizen science. Participant confidence significantly increases once a volunteer has carried out a survey – but this does not show any relationship with accuracy. It is concluded that estimation of abundance must be embedded with training and validation methods, and it is recommended further work is carried out into robust online training and validation

Flucytosine and cryptococcosis: time to urgently address the worldwide accessibility of a 50-year-old antifungal.

Current, widely accepted guidelines for the management of HIV-associated cryptococcal meningoencephalitis (CM) recommend amphotericin B combined with flucytosine (5-FC) for ≥2 weeks as the initial induction treatment of choice. However, access to flucytosine in Africa and Asia, where disease burden is greatest, is inadequate at present. While research into identifying effective and well-tolerated antifungal combinations that do not contain flucytosine continues, an ever-increasing body of evidence from in vitro, in vivo and clinical studies points to the benefits of flucytosine in the treatment of CM in both intravenous combinations with amphotericin B and oral combinations with high-dose fluconazole. This article provides an up-to-date review of this evidence, and the current issues and challenges regarding increasing access to this key component of combination antifungal therapy for cryptococcosis

Drought-Induced Amplification of Saint Louis encephalitis virus, Florida

We used a dynamic hydrology model to simulate water table depth (WTD) and quantify the relationship between Saint Louis encephalitis virus (SLEV) transmission and hydrologic conditions in Indian River County, Florida, from 1986 through 1991, a period with an SLEV epidemic. Virus transmission followed periods of modeled drought (specifically low WTDs 12 to 17 weeks before virus transmission, followed by a rising of the water table 1 to 2 weeks before virus transmission). Further evidence from collections of Culex nigripalpus (the major mosquito vector of SLEV in Florida) suggests that during extended spring droughts vector mosquitoes and nestling, juvenile, and adult wild birds congregate in selected refuges, facilitating epizootic amplification of SLEV. When the drought ends and habitat availability increases, the SLEV-infected Cx. nigripalpus and wild birds disperse, initiating an SLEV transmission cycle. These findings demonstrate a mechanism by which drought facilitates the amplification of SLEV and its subsequent transmission to humans

An inter-comparison of Arctic synoptic scale storms between four global reanalysis datasets

The Arctic is becoming more accessible as sea ice extent continues to decline, resulting in higher human exposure to Arctic storms. This study compares Arctic storm characteristics between the ECMWF-Interim Reanalysis, 55-year Japanese Reanalysis, NASA-Modern Era Retrospective Analysis for Research and Applications Version 2 and National Centre for Environmental Prediction-Climate Forecast System Reanalysis datasets between 1980 and 2017, in winter (DJF) and summer (JJA). It is shown that Arctic storm characteristics are sensitive to the variable used for storm tracking. Arctic storm frequency is found to be similar in summer and winter when using sea level pressure minima to track Arctic storms, whereas, the storm frequency is found to be higher in winter than summer when using 850 hPa relative vorticity to track storms, based on using the same storm tracking algorithm. It is also found that there are no significant trends in Arctic storm characteristics between 1980 and 2017. Given the sparsity of observations in the Arctic, it might be expected that there are large differences in Arctic storm characteristics between the reanalysis datasets. Though, some similar Arctic storm characteristics are found between the reanalysis datasets, it is found that the differences in Arctic storm characteristics between the reanalysis datasets are generally higher in winter than in summer. Overall, the results show that there are differences in Arctic storm characteristics between reanalysis datasets, but even larger differences can arise between using 850 hPa relative vorticity or mean sea level pressure as the storm tracking variable, which adds to the uncertainty associated with current Arctic storm characteristics

Serving children: the impact of poverty on children's experiences of services

This study arose from the identification of a gap in knowledge and corresponding need for the development of a better contemporary understanding of children's experiences of poverty. Focusing on children aged 10 - 14 years, the study aimed to provide a perspective on the lives of children and young people affected by poverty in Scotland through comparing the experiences of children living in poverty with those more economically advantaged