The Objectification of Women in Cane

This thesis examines Jean Toomer\u27s Cane (1923) from a feminist perspective. Using Laura Mulvey\u27s film theory of the male gaze , it repurposes it and uses the theory from a literary standpoint. Throughout this thesis, many different aspects are examined including the character interaction within the stories, the use of the narrative I and its overarching implications, audience participation with regard to voyeurism and Toomer\u27s paradoxical stance on the objectification of women. Toomer writes about the women in Cane in a sexually explicit fashion, but does so in order to draw attention to the gaze and criticize it. As the vignettes in Cane progress, the women--some complacent with the gaze, others even participants--gain agency and the ability to return the male gaze, culminating in a possible relationship between Kabnis and Carrie K., a relationship of equal

Bioreactor scale-up harmonization - From process development to manufacturing

Successful bioprocess scale up requires an understanding of the microenvironment influenced by bioreactor parametric conditions and the effect on cellular metabolism and expression of a recombinant protein. While, significant understanding of best practices exists in scaling up bioprocesses, Contract Development and Manufacturing Organizations (CDMO) have a unique challenge in requiring a working knowledge of our bioreactor capabilities driven by a diverse client network and thus a need for a ready-to-implement scale up platform for a wide range of molecule types. An effective CDMO must be able to scale-up client platform processes (which differ for each client) as well as utilize its knowledge to help smaller client firms with minimal knowledge of scale-up. This challenge is increased for novel innovator molecules, biosimilar candidates, and existing mAb processes transferred from other facilities. Moreover, the addition of novel, disposable bioreactors makes evident the need to harmonize scale up strategies for bioreactors with different geometric characteristics as is typically found in manufacturing settings. In this work we present an integrated approach to characterizing different scale bioreactors from process development through manufacturing. Approaches include a combination of process mixing empirical correlations for scale-up dependent parameters and computational fluid dynamics (CFD) models as well as experimental data to enable scientific judgment on scale-up. Methodologies used to define scale up model are complementary and represent the starting point for characterizing bioreactors and achieved harmonization across scales. Discussion will be presented on strategies used to achieve comparability between CFD models, correlations and experimental data. Agreement between components of this approach is represented in design charts including mixing time, kLa and power per volume (P/V). (See Figure 1) The combination of strategies resulted in a structured methodology to define engineering design space for various processes based on models and experimental data. Successful outcomes for multiple products on process performance for cell culture processing such as growth, titer, metabolic performance and product quality attributes are compared between 2L, 20L and 2500L reactor

Configurational density of states and melting of simple solids

We analyze the behavior of the microcanonical and canonical caloric curves for a piecewise model of the configurational density of states of simple solids, in the context of melting from the superheated state, as realized numerically in the Z-method via atomistic molecular dynamics. A first-order phase transition with metastable regions is reproduced by the model, being therefore useful to describe aspects of the melting transition. Within this model, transcendental equations connecting the superheating limit, the melting point, and the specific heat of each phase are presented and numerically solved. Our results suggest that the essential elements of the microcanonical Z curves can be extracted from simple modeling of the configurational density of states

Passo A Passo, Seu Caminho: Guia Curricular Para O Ensino De Habilidades Básicas

Educar crianças é tarefa das mais complexas. Ela exige do educador um perfil todo especial: é preciso formação sólida sobre os processos de aprendizagem e desenvolvimento humano, conhecimento aprofundado da clientela com a qual se trabalhará, sensibilidade na aplicação da teoria à prática e flexibilidade para - frente ao novo ou ao não esperado - ser capaz de alterar os rumos previstos. Ensinar crianças requer, sobretudo, clareza sobre os objetivos que se pretende atingir, certeza da importância do processo formativo e segurança para exercê-lo bem. Todas estas qualidades transparecem no texto de Margarida H. Windholz: "Passo a Passo, Seu Caminho: Um Guia Curricular para o Ensino de Habilidades Básicas"

The connection between mass, environment and slow rotation in simulated galaxies

Recent observations from integral field spectroscopy (IFS) indicate that the fraction of galaxies that are slow rotators, $F_{\rm SR}$, depends primarily on stellar mass, with no significant dependence on environment. We investigate these trends and the formation paths of slow rotators (SRs) using the EAGLE and Hydrangea hydro-dynamical simulations. EAGLE consists of several cosmological boxes of volumes up to $(100\,\rm Mpc)^3$, while Hydrangea consists of $24$ cosmological simulations of galaxy clusters and their environment. Together they provide a statistically significant sample in the stellar mass range $10^{9.5}\,\rm M_{\odot}-10^{12.3}\,\rm M_{\odot}$, of $16,358$ galaxies. We construct IFS-like cubes and measure stellar spin parameters, $\lambda_{\rm R}$, and ellipticities, allowing us to classify galaxies into slow/fast rotators as in observations. The simulations display a primary dependence of $F_{\rm SR}$ on stellar mass, with a weak dependence on environment. At fixed stellar mass, satellite galaxies are more likely to be SRs than centrals. $F_{\rm SR}$ shows a dependence on halo mass at fixed stellar mass for central galaxies, while no such trend is seen for satellites. We find that $\approx 70$% of SRs at $z=0$ have experienced at least one merger with mass ratio $\ge 0.1$, with dry mergers being at least twice more common than wet mergers. Individual dry mergers tend to decrease $\lambda_{\rm R}$, while wet mergers mostly increase it. However, $30$% of SRs at $z=0$ have not experienced mergers, and those inhabit halos with median spins twice smaller than the halos hosting the rest of the SRs. Thus, although the formation paths of SRs can be varied, dry mergers and/or halos with small spins dominate.Comment: Accepted for publications in MNRAS (20 pages, 17 main body, 1.5 appendix). Changes include analysis of the orbital angular momentum effect on lambdaR and slightly different ellipticity calculatio