1,615 research outputs found

    Output from Bose condensates in tunnel arrays: the role of mean-field interactions and of transverse confinement

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    We present numerical studies of atomic transport in 3D and 1D models for a mode-locked, pulsed atom laser as realized by Anderson and Kasevich [Science 281 (1998) 1686] using an elongated Bose condensate of 87{}^{87}Rb atoms poured into a vertical optical lattice. From our 3D results we ascertain in a quantitative manner the role of mean-field interactions in determining the shape and the size of the pulses in the case of Gaussian transverse confinement. By comparison with 1D simulations we single out a best-performing 1D reduction of the mean-field interactions, which yields quantitatively useful predictions for all main features of the matter output.Comment: 12 pages, 2 figure

    Return to work and workplace activity limitations following total hip or knee replacement

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    SummaryObjectiveTotal hip (THR) and knee (TKR) replacements increasingly are performed on younger people making return to work a salient outcome. This research evaluates characteristics of individuals with early and later return to work following THR and TKR. Additionally, at work limitations pre-surgery and upon returning to work, and factors associated with work limitations were evaluated.Methods190 THR and 170 TKR of a total 931 cohort participants were eligible (i.e., working or on short-term disability pre-surgery). They completed questionnaires pre-surgery and 1, 3, 6 and 12 months post-surgery that included demographics, type of occupation, and the Workplace Activity Limitations Scale (WALS).Results166 (87%) and 144 (85%) returned to work by 12 months following THR and TKR, respectively. Early (1 month) return to work was associated with, male gender, university education, working in business, finance or administration, and low physical demand work. People with THR returned to work earlier than those with TKR. For both groups, less pain and every day functional limitations were associated with less workplace activity limitations at the time return to work.ConclusionsThe majority of individuals working prior to surgery return to work following hip or knee replacement for osteoarthritis (OA) and experience fewer limitations at work than pre-surgery. The changing workforce dynamics and trends toward surgery at younger ages mean that these are important outcomes for clinicians to assess. Additionally, this is important information for employers in understanding continued participation in employment for people with OA

    Phylogenetics of Archerfishes (Toxotidae) and Evolution of the Toxotid Shooting Apparatus

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    A grant from the One-University Open Access Fund at the University of Kansas was used to defray the author's publication fees in this Open Access journal. The Open Access Fund, administered by librarians from the KU, KU Law, and KUMC libraries, is made possible by contributions from the offices of KU Provost, KU Vice Chancellor for Research & Graduate Studies, and KUMC Vice Chancellor for Research. For more information about the Open Access Fund, please see http://library.kumc.edu/authors-fund.xml.Archerfishes (Toxotidae) are variously found in the fresh- and brackish-water environments of Asia Pacific and are well known for their ability to shoot water at terrestrial prey. These shots of water are intended to strike their prey and cause it to fall into the water for capture and consumption. While this behavior is well known, there are competing hypotheses (blowpipe vs. pressure tank hypothesis) of how archerfishes shoot and which oral structures are involved. Current understanding of archerfish shooting structures is largely based on two species, Toxotes chatareus and T. jaculatrix. We do not know if all archerfishes possess the same oral structures to shoot water, if anatomical variation is present within these oral structures, or how these features have evolved. Additionally, there is little information on the evolution of the Toxotidae as a whole, with all previous systematic works focusing on the interrelationships of the family. We first investigate the limits of archerfish species using new and previously published genetic data. Our analyses highlight that the current taxonomy of archerfishes does not conform to the relationships we recover. Toxotes mekongensis and T. siamensis are placed in the synonymy of T. chatareus, Toxotes carpentariensis is recognized as a species and removed from the synonymy of T. chatareus, and the genus Protoxotes is recognized for T. lorentzi based on the results of our analyses. We then take an integrative approach, using a combined analysis of discrete hard- and soft-tissue morphological characters with genetic data, to construct a phylogeny of the Toxotidae. Using the resulting phylogenetic hypothesis, we then characterize the evolutionary history and anatomical variation within the archerfishes. We discuss variation in the oral structures and the evolution of the mechanism with respect to the interrelationships of archerfishes, and find that the oral structures of archerfishes support the blowpipe hypothesis but soft-tissue oral structures may also play a role in shooting. Finally, by comparing the morphology of archerfishes to their sister group, we find that the Leptobramidae has relevant shooting features in the oral cavity, suggesting that some components of the archerfish shooting mechanism are examples of co-opted or exapted traits

    Biofluorescence in Catsharks (Scyliorhinidae): Fundamental description and relevance for elasmobranch visual ecology

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    Biofluorescence has recently been found to be widespread in marine fishes, including sharks. Catsharks, such as the Swell Shark (Cephaloscyllium ventriosum) from the eastern Pacific and the Chain Catshark (Scyliorhinus retifer) from the western Atlantic, are known to exhibit bright green fluorescence. We examined the spectral sensitivity and visual characteristics of these reclusive sharks, while also considering the fluorescent properties of their skin. Spectral absorbance of the photoreceptor cells in these sharks revealed the presence of a single visual pigment in each species. Cephaloscyllium ventriosum exhibited a maximum absorbance of 484 +/- 3 nm and an absorbance range at half maximum (lambda(1/2max)) of 440-540 nm, whereas for S. retifer maximum absorbance was 488 +/- 3 nm with the same absorbance range. Using the photoreceptor properties derived here, a "shark eye" camera was designed and developed that yielded contrast information on areas where fluorescence is anatomically distributed on the shark, as seen from other sharks' eyes of these two species. Phylogenetic investigations indicate that biofluorescence has evolved at least three times in cartilaginous fishes. The repeated evolution of biofluorescence in elasmobranchs, coupled with a visual adaptation to detect it; and evidence that biofluorescence creates greater luminosity contrast with the surrounding background, highlights the potential importance of biofluorescence in elasmobranch behavior and biology

    1H, 13C, and 15N resonance assignments of a conserved putative cell wall binding domain from Enterococcus faecalis

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    Enterococcus faecalis is a major causative agent of hospital acquired infections. The ability of E. faecalis to evade the host immune system is essential during pathogenesis, which has been shown to be dependent on the complete separation of daughter cells by peptidoglycan hydrolases. AtlE is a peptidoglycan hydrolase which is predicted to bind to the cell wall of E. faecalis, via six C-terminal repeat sequences. Here, we report the near complete assignment of one of these six repeats, as well as the predicted backbone structure and dynamics. This data will provide a platform for future NMR studies to explore the ligand recognition motif of AtlE and help to uncover its potential role in E. faecalis virulence

    Effects of old landfills on groundwater quality. Phase 2, investigation of the Thriplow landfill 1996–1997

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    Disused sand and gravel excavations overlying the major Chalk aquifer at Thriplow in Cambridgeshire have been filled with domestic waste in two phases. One area (Phase 1) was filled between 1957–77 with little compaction of the refuse and was left uncapped, while Phase 2 was deposited between 1981–87 and capped with clay. Aerial photography and surface resistivity surveys indicate that the site geometry is complex, with several phases of landfilling into excavations of differing depths. Drilling through the waste indicates that leachate production and waste stabilisation proceed at different rates in capped and uncapped landfills. Analysis of leachate obtained by centrifugation or squeezing appears to give more insight into the pollution potential than do leach tests with distilled water. The Biological Methane Potential (BMP) of the waste appears to be related to the quantity of decomposable material but the chemical oxygen demand (COD) values are distorted by the presence of reduced metals. Too few boreholes have been drilled to define the leachate source in terms of its spatial distribution and little is known of how its composition has changed with time. However, hydraulic conductivity measurements on the landfill caps suggest that it is sufficiently permeable for all rainfall to potentially infiltrate the waste. Boreholes outside the landfill penetrate the Upper and Lower Chalk, and identify the Melbourn Rock and underlying Plenus Marls at the junction of the two formations about 20 m below ground level (bgl). Surface resistivity surveys using the BGS RESCAN system, confirm aerial photographs of the extent of the landfill and also suggest that leachate has migrated beyond the base of the landfill. Evidence of leachate migration in pre-existing screened boreholes completed above and below the Plenus Marls suggests that leachate is flowing above the Plenus Marls. Hydraulic head measurements whilst drilling a borehole to the base of the lower Chalk approx. 70 m bgl revealed the potential for upward groundwater flow through the Plenus Marls. Thus, previously-drilled boreholes penetrating the Plenus Marls are expected to recharge upwards into the shallow aquifer above the Plenus Marls diluting any leachate in the upper aquifer and distorting the flow regime. Several of these boreholes have subsequently been modified to stem the flow across the Plenus Marls. One borehole down-gradient to the west of the site revealed a large thickness of drift composed of both sand and clay rich material. This suggests the existence of a buried channel, the hydrogeological significance of which has yet to be assessed. Groundwater chemistry appears to be influenced by three major factors. (a) the landfill leachate (b) the composition of shallow groundwater in the top 10 m of the Chalk, and (c) the composition of water from the Lower Chalk. Limited groundwater monitoring data appear to display a cyclic variation in chloride concentration. The origin for this is not clear but it may correlate with cyclic variations in groundwater levels when the water table rises into the waste. Cyclic flushing of the landfill may release leachate into the aquifer giving rise to pulses of chloride. Alternatively changes in chloride may arise by the changing direction of groundwater flow which as yet has not been assessed. A conceptual hydrogeological model in which flow is limited to above the Plenus Marls has been used to develop a more appropriate groundwater flow and solute transport model. However, the model lacks data on aquifer properties, on contaminant inputs concentrations, fluxes and spatial variations, and there is a paucity of monitoring data for calibration. Nonetheless preliminary transport modelling using an equivalent porous medium approach shows that an effective porosity of about 5% best fits the regional data. Since this is much less than the total porosity of about 40% for the Chalk, it would appear that only part of the Chalk is available for flow but that matrix diffusion could play an important role in leachate attenuation. Discrete fracture modelling using the FRACTRAN code has allowed some scoping to be made of the hydraulic properties of the aquifer by comparison with chloride hydrographs, but these again need to be better conditioned by in-situ measurement of fracture distributions and transmissivities. A number of additional activities are required to improve the understanding of flow and contaminant transport at the site. These include better spatial definition of the waste distribution, improved data on the hydraulic properties of the Chalk aquifer, and the use of automatic monitoring to record temporal changes in groundwater chemistry and groundwater levels

    Defining the origins of multiple emission/excitation in rhenium-bisthiazole complexes

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    The underlying mechanism of the unusual emissive behavior of [Re(CO) 3 -1,1-bis-4-thiazole-(1,4)-diaminobutane)] bromide (4-BT) has been investigated. Synthesis and spectroscopic characterization of structurally similar isomers ([Re(CO) 3 -1,1-bis-2-thiazole-(1,4)-diaminobutane)] bromide (2-BT)) and the location of triplet states, solid state and low temperature spectroscopic measurements, and DFT calculations show that the photophysical properties are not due to photoisomerization as previously hypothesized. The results show that the unusual emissive behavior is not observed in structural isomers, is specific to the previously reported complex, 4-BT, and may arise from vibrational energy relaxation and vibrational cooling. Translation of the unusual emissive behavior to the solid state offers an interesting platform allowing this complex to be potentially utilized as a probe, sensor or photonic device

    Feline parvovirus seroprevalence is high in domestic cats from disease outbreak and non-outbreak regions in Australia

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    Multiple, epizootic outbreaks of feline panleukopenia (FPL) caused by feline parvovirus (FPV) occurred in eastern Australia between 2014 and 2018. Most affected cats were unvaccinated. We hypothesised that low population immunity was a major driver of re-emergent FPL. The aim of this study was to (i) determine the prevalence and predictors of seroprotective titres to FPV among shelter-housed and owned cats, and (ii) compare the prevalence of seroprotection between a region affected and unaffected by FPL outbreaks. FPV antibodies were detected by haemagglutination inhibition assay on sera from 523 cats and titres ≥1:40 were considered protective. Socioeconomic indices based on postcode and census data were included in the risk factor analysis. The prevalence of protective FPV antibody titres was high overall (94.3%), even though only 42% of cats were known to be vaccinated, and was not significantly different between outbreak and non-outbreak regions. On multivariable logistic regression analysis vaccinated cats were 29.94 times more likely to have protective FPV titres than cats not known to be vaccinated. Cats from postcodes of relatively less socioeconomic disadvantage were 5.93 times more likely to have protective FPV titres. The predictors identified for FPV seroprotective titres indicate targeted vaccination strategies in regions of socioeconomic disadvantage would be beneficial to increase population immunity. The critical level of vaccine coverage required to halt FPV transmission and prevent FPL outbreaks should be determined

    Cosmological parameter estimation using Very Small Array data out to ℓ= 1500

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    We estimate cosmological parameters using data obtained by the Very Small Array (VSA) in its extended configuration, in conjunction with a variety of other cosmic microwave background (CMB) data and external priors. Within the flat Λ cold dark matter (ΛCDM) model, we find that the inclusion of high-resolution data from the VSA modifies the limits on the cosmological parameters as compared to those suggested by the Wilkinson Microwave Anisotropy Probe (WMAP) alone, while still remaining compatible with their estimates. We find that Ωbh2= 0.0234+0.0012−0.0014, Ωdmh2= 0.111+0.014−0.016, h= 0.73+0.09−0.05, nS= 0.97+0.06−0.03, 1010AS= 23+7−3 and τ= 0.14+0.14−0.07 for WMAP and VSA when no external prior is included. On extending the model to include a running spectral index of density fluctuations, we find that the inclusion of VSA data leads to a negative running at a level of more than 95 per cent confidence ( nrun=−0.069 ± 0.032 ), something that is not significantly changed by the inclusion of a stringent prior on the Hubble constant. Inclusion of prior information from the 2dF galaxy redshift survey reduces the significance of the result by constraining the value of Ωm. We discuss the veracity of this result in the context of various systematic effects and also a broken spectral index model. We also constrain the fraction of neutrinos and find that fν < 0.087 at 95 per cent confidence, which corresponds to mν < 0.32 eV when all neutrino masses are equal. Finally, we consider the global best fit within a general cosmological model with 12 parameters and find consistency with other analyses available in the literature. The evidence for nrun < 0 is only marginal within this model
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