Sanitation and sewage disposal for country homes

"September, 1910.""The demand for modernly equipped farm homes at a moderate cost is becoming an urgent one. Farmers throughout Missouri are striving to keep abreast of the times in modern methods of agriculture. Likewise they are seeking the latest and best practices in every line of activity pertaining to the industry of farming. They are demanding that their homes be equipped with the same modern conveniences that the people of the city enjoy, and it is the call from them for information on modern farm sanitation that has led to the publication of this bulletin. The greater part of the bulletin is devoted to the subject of modern sewage disposal plants for isolated houses. A portion has been given to the discussion of sewage disposal methods now employed on the farm, and still another portion to country plumbing. It is the purpose of this bulletin to present several specific designs and to call attention to the necessity of home sanitation in a general way."--Introductio

Sam Houston and the Indians : a rhetorical study of the man and the myth

Dissertation (Ph.D.)--University of Kansas, Speech and Drama, 1971

Developing a Sustainable Approach to Emerald Ash Borer Management

Emerald ash borer, Agrilus planipennis Fairmaire, is an invasive wood boring beetle native to eastern Asia which was first detected in North America in 2002. All North American Fraxinus (ash) species are suitable hosts and susceptible to attack. Emerald ash borer larvae feed on phloem beneath the bark of infested trees resulting in girdling and mortality in as little as five years following initial infestation. Since its introduction near Detroit, Michigan, emerald ash borer has rapidly spread throughout much of the United States and portions of Canada, threatening the persistence of ash in invaded regions. I tested a management strategy for emerald ash borer which combines pesticide applications with releases of three species of classical biological control agents: Tetrastichus planipennisi, Spathius agrili, and Oobius agrili. My data suggest that the two approaches are compatible and pesticides did not negatively impact establishment success of T. planipennisi and O. agrili. Additionally, I characterized the assemblage of natural enemies native to the central United States that might be capable of helping regulate emerald ash borer populations, and found twelve morpho-species of natural enemies being recruited to emerald ash borer in this region. Finally, I evaluated the impact of ash decline on native hymenopteran parasitoids and found a positive correlation between ash decline and parasitoid abundance

Messenger RNA coding for only the alpha subunit of the rat brain Na channel is sufficient for expression of functional channels in Xenopus oocytes

Several cDNA clones coding for the high molecular weight (alpha) subunit of the voltage-sensitive Na channel have been selected by immunoscreening a rat brain cDNA library constructed in the expression vector lambda gt11. As will be reported elsewhere, the amino acid sequence translated from the DNA sequence shows considerable homology to that reported for the Electrophorus electricus electroplax Na channel. Several of the cDNA inserts hybridized with a low-abundance 9-kilobase RNA species from rat brain, muscle, and heart. Sucrose-gradient fractionation of rat brain poly(A) RNA yielded a high molecular weight fraction containing this mRNA, which resulted in functional Na channels when injected into oocytes. This fraction contained undetectable amounts of low molecular weight RNA. The high molecular weight Na channel RNA was selected from rat brain poly(A) RNA by hybridization to a single-strand antisense cDNA clone. Translation of this RNA in Xenopus oocytes resulted in the appearance of tetrodotoxin-sensitive voltage-sensitive Na channels in the oocyte membrane. These results demonstrate that mRNA encoding the alpha subunit of the rat brain Na channel, in the absence of any beta-subunit mRNA, is sufficient for translation to give functional channels in oocytes

Harvest Rates and Efforts of Avid Quail Hunters in East Central Mississippi

Six avid quail hunters had an average daily harvest rate of 6.39 (4.97-8.55) and average seasonal harvest of 298 (116-530); they averaged 47 (28-60) hunts or days afield per year for a period of 2-10 years. The avid hunters averaged three to four hunts per week, and the hunts lasted three to four hours. Two hunters often had hunting guests, and the total season harvest by guests averaged 117 (63-211) with one hunter and 121 (56-178) with the other hunter. A seventh avid quail hunter usually had quests, with an average hunting party of 2.45; they harvested an average of 449 (388-510) quail per year over a two year period. Quail harvested per hour of effort ranged from 0.95 to 2.2 . Harvest rates and efforts of avid quail hunters were much greater than those of average quail hunters depicted in hunter mail questionnaire surveys

Informing Practice through Collaborative Partnerships

This paper focuses on students and their teacher engaging in authentic tasks and materials couched in problem-oriented formats within meaningful learning contexts that foster thinking and learning. Authentic in that students construct meaning from real data and are asked to make sense of the world around them. Students pursue individual paths of inquiry using critical and imaginative thinking, and engage in social and solitary contexts that involve them in writing, intervening, and reflecting on ideas gleaned from conversations and readings (electronic and conventional) with a university educator and NASA science educator. The process engages students in formal skills such as written communication, literacy, logic, and calculation using an innovative electronic interactive network. Evaluations of timed writings, concept maps, and Vee diagrams are presente

Short-Pulse, Compressed Ion Beams at the Neutralized Drift Compression Experiment

We have commenced experiments with intense short pulses of ion beams on the Neutralized Drift Compression Experiment (NDCX-II) at Lawrence Berkeley National Laboratory, with 1-mm beam spot size within 2.5 ns full-width at half maximum. The ion kinetic energy is 1.2 MeV. To enable the short pulse duration and mm-scale focal spot radius, the beam is neutralized in a 1.5-meter-long drift compression section following the last accelerator cell. A short-focal-length solenoid focuses the beam in the presence of the volumetric plasma that is near the target. In the accelerator, the line-charge density increases due to the velocity ramp imparted on the beam bunch. The scientific topics to be explored are warm dense matter, the dynamics of radiation damage in materials, and intense beam and beam-plasma physics including select topics of relevance to the development of heavy-ion drivers for inertial fusion energy. Below the transition to melting, the short beam pulses offer an opportunity to study the multi-scale dynamics of radiation-induced damage in materials with pump-probe experiments, and to stabilize novel metastable phases of materials when short-pulse heating is followed by rapid quenching. First experiments used a lithium ion source; a new plasma-based helium ion source shows much greater charge delivered to the target.Comment: 4 pages, 2 figures, 1 table. Submitted to the proceedings for the Ninth International Conference on Inertial Fusion Sciences and Applications, IFSA 201

Depression and Clinical Inertia in Patients With Uncontrolled Hypertension

Depression is a known risk factor for poor prognosis among patients with cardiovascular disease.1 Numerous biological and behavioral mechanisms have been proposed.2 However, few studies have investigated the association between depression and “clinical inertia,” or lack of treatment intensification in individuals not at evidence-based goals for care.3 To address this gap, we assessed whether a diagnosis of depression is associated with clinical inertia in patients with uncontrolled hypertension

Detection of Dynamic Spatiotemporal Response to Periodic Chemical Stimulation in a Xenopus Embryonic Tissue

Embryonic development is guided by a complex and integrated set of stimuli that results in collective system-wide organization that is both time and space regulated. These regulatory interactions result in the emergence of highly functional units, which are correlated to frequency-modulated stimulation profiles. We have determined the dynamic response of vertebrate embryonic tissues to highly controlled, time-varying localized chemical stimulation using a microfluidic system with feedback control. Our approach has enabled localized spatiotemporal manipulation of the steroid hormone dexamethasone (DEX) in Animal Cap (AC) tissues isolated from gastrulating Xenopus embryos. Using this approach we investigated cell-scale responses to precisely controlled stimulation by tracking the redistribution of a GFP-tagged DEX-reporter constructed from the human glucocorticoid receptor (GR). We exposed defined regions of a single AC explant to different stimulation conditions—continuous stimulation, periodic stimulation, and no stimulation. We observed collective behavior of the GR transport into the nucleus was first-order. Furthermore, the dynamic response was well-modeled by a first-order differential equation with a single time derivative. The model predicted that responses to periodic stimulations closely matched the results of the frequency-based experiments. We find that stimulation with localized bursts versus continuous stimulation can result in highly distinct responses. This finding is critical as controlled space and time exposure to growth factors is a hallmark of complex processes in embryonic development. These complex responses to cellular signaling and transport machinery were similar to emergent behaviors in other complex systems, suggesting that even within a complex embryonic tissue, the overall system can converge toward a predictive first-order response

Mipomersen, an Apolipoprotein B Synthesis Inhibitor, Reduces Atherogenic Lipoproteins in Patients With Severe Hypercholesterolemia at High Cardiovascular Risk A Randomized, Double-Blind, Placebo-Controlled Trial

ObjectivesThis study sought to examine the efficacy and safety of mipomersen for reducing atherogenic lipids and lipoproteins in patients with hypercholesterolemia.BackgroundMany patients on lipid-lowering therapies remain unable to achieve target low-density lipoprotein (LDL) cholesterol levels. Mipomersen, an antisense oligonucleotide inhibitor of apolipoprotein B, reduces LDL cholesterol and atherogenic lipoproteins.MethodsThis randomized, double-blind, multicenter study enrolled 158 patients with baseline LDL cholesterol levels ≥100 mg/dl with, or at high risk for, coronary heart disease who were receiving maximally tolerated lipid-lowering therapy. Patients received weekly subcutaneous mipomersen 200 mg (n = 105) or placebo (n = 52) for 26 weeks, with a 24-week follow-up period. Randomization was stratified by type 2 diabetes status.ResultsSixty mipomersen and 44 placebo patients completed treatment. Mean baseline LDL cholesterol levels were 122.7 and 122.6 mg/dl in the placebo and mipomersen patients, respectively. Mipomersen reduced LDL cholesterol by −36.9% compared with placebo at −4.5% (p < 0.001). Target LDL cholesterol <100 mg/dl was attained in 76% of mipomersen and 38% of placebo patients. Mipomersen also significantly reduced apolipoprotein B (−38%) and lipoprotein(a) (−24%) (p < 0.001). Common adverse events included injection site reactions (78% with mipomersen, 31% with placebo) and flu-like symptoms (34% with mipomersen, 21% with placebo). Elevations in transaminases and liver fat also occurred in some patients, and these levels returned toward baseline after treatment cessation.ConclusionsMipomersen significantly reduced LDL cholesterol, apolipoprotein B, and lipoprotein(a) in patients with hypercholesterolemia with, or at risk for, coronary heart disease not controlled by existing therapies. (Safety and Efficacy of Mipomersen [ISIS 301012] as Add-On Therapy in High Risk Hypercholesterolemic Patients; NCT00770146