Polyhedral Combinatorics of UPGMA Cones

Distance-based methods such as UPGMA (Unweighted Pair Group Method with Arithmetic Mean) continue to play a significant role in phylogenetic research. We use polyhedral combinatorics to analyze the natural subdivision of the positive orthant induced by classifying the input vectors according to tree topologies returned by the algorithm. The partition lattice informs the study of UPGMA trees. We give a closed form for the extreme rays of UPGMA cones on n taxa, and compute the normalized volumes of the UPGMA cones for small n. Keywords: phylogenetic trees, polyhedral combinatorics, partition lattic

A study of prematurely and routinely discharged patients from Louisville General Hospital in 1946.

In July 1946 the Board of Health of Louisville and Jefferson County, Kentucky, announced its decision to curtail services of the public health department serving the metropolitan area surrounding and including Louisville, and the outlying agricultural region in the rural part of Jefferson County. In the past decade the combined health department for Louisville and for Jefferson County had accomplished much for the health needs of the citizens of the community. The close association, as a teaching hospital, with the University of Louisville Medical School, had helped General Hospital, the former municipal hospital known as City Hospital to become a good general hospital with fairly adequate ward and clinic facilities. Therefore, it was with regret that the Health Board decided to curtail service Just when it was most needed, as returning servicemen, and new family groups; industrial workers attracted by new industry locating in Louisville and the surrounding county; and families attracted by the expansion of business in the growing metropolitan area, made Louisville an increasingly important city in the nation

Characterizing Food Insecurity at a Northeast Land-grant University

In 2015, 15.8 million U.S. households were food insecure. While nationally food insecurity is assessed at the household and childhood level, university students are not explicitly monitored. The purpose of this study was to determine the prevalence of food insecurity at a northeast land grant university and characterize the contributing factors. A pilot study (n=211) was conducted in fall 2014 among a general nutrition class and found that 12.4% of students were food insecure, with another 5.7% reported marginal food security. A larger, university wide survey among graduate and undergraduate students was conducted in fall 2015 (n=943) and found that 25% of students were food insecure and 9.6% had marginal food security. Students who reported receiving financial aid or identified as a first generation student were more likely to be food insecure (OR 1.84, p=0.007; OR 1.73, p=0.006, respectively). In-person interviews (n=5) found that very low food secure students were frequently eating 1-2 meals a day and were unable to afford fresh produce despite the desire to include in their diet. However, students reported that if things “got worse” they could ask their parents for help. Collectively this work expands our understanding of food insecurity on a university campus

Wistful and Blue

With Ukulele arrangement. Contains advertisements and/or short musical examples of pieces being sold by publisher.https://digitalcommons.library.umaine.edu/mmb-vp/7140/thumbnail.jp

Evidence for regulatory diversity and auto-regulation at the TAC1 locus in sensory neurones

Peer reviewedPublisher PD