Characterization and Comparison of the 10-2 SITA-Standard and Fast Algorithms

Purpose: To compare the 10-2 SITA-standard and SITA-fast visual field programs in patients with glaucoma. Methods: We enrolled 26 patients with open angle glaucoma with involvement of at least one paracentral location on 24-2 SITA-standard field test. Each subject performed 10-2 SITA-standard and SITA-fast tests. Within 2 months this sequence of tests was repeated. Results: SITA-fast was 30% shorter than SITA-standard (5.5 ± 1.1 vs 7.9 ± 1.1 minutes, P < 0.001). Mean MD was statistically significantly higher for SITA-standard compared with SITA-fast at first visit (Δ = 0.3 dB, P = 0.017) but not second visit. Inter-visit difference in MD or in number of depressed points was not significant for both programs. Bland-Altman analysis showed that clinically significant variations can exist in individual instances between the 2 programs and between repeat tests with the same program. Conclusions: The 10-2 SITA-fast algorithm is significantly shorter than SITA-standard. The two programs have similar long-term variability. Average same-visit between-program and same-program between-visit sensitivity results were similar for the study population, but clinically significant variability was observed for some individual test pairs. Group inter- and intra-program test results may be comparable, but in the management of the individual patient field change should be verified by repeat testing

Opto-Mechanical Interactions in Multi-Core Optical Fibers and Their Applications

[EN] Optical fibers containing multiple cores are being developed towards capacity enhancement in space-division multiplexed optical communication networks. In many cases, the fibers are designed for negligible direct coupling of optical power among the cores. The cores remain, however, embedded in a single, mechanically-unified cladding. Elastic (or acoustic) modes supported by the fiber cladding geometry are in overlap with multiple cores. Acoustic waves may be stimulated by light in any core through electrostriction. Once excited, the acoustic waves may induce photo-elastic perturbations to optical waves in other cores as well. Such opto-mechanical coupling gives rise to inter-core cross-phase modulation effects, even when direct optical crosstalk is very weak. The cross-phase modulation spectrum reaches hundreds of megahertz frequencies. It may consist of discrete and narrow peaks, or may become quasi-continuous, depending on the geometric layout. The magnitude of the effect at the resonance frequencies is comparable with that of intra-core cross-phase modulation due to Kerr nonlinearity. Two potential applications are demonstrated: single-frequency opto-electronic oscillators that do not require radio-frequency electrical filters, and point-sensing of liquids outside the cladding of multi-core fibers, where light cannot reach.This work was supported in part by a Starter Grant from the European Research Council (ERC) under Grant H2020-ERC-2015-STG 679228 (L-SID), in part by the Israeli Ministry of Science and Technology under Grant 61047, and in part by the Spanish Ministry of Economy and Competitiveness under the DIMENSION TEC2017 88029-R Project. H. H. Diamandi was supported by the Azrieli Foundation for the award of an Azrieli Fellowship. The work of J. Madrigal was supported by Universitat Politecnica de Valencia scholarship PAID-01-18. The work of D. Barrera was supported by Spanish MICINN fellowship IJCI-2017-32476.Diamandi, HH.; London, Y.; Bergman, A.; Bashan, G.; Madrigal-Madrigal, J.; Barrera, D.; Sales Maicas, S.... (2020). Opto-Mechanical Interactions in Multi-Core Optical Fibers and Their Applications. IEEE Journal of Selected Topics in Quantum Electronics. 26(4):1-13. https://doi.org/10.1109/JSTQE.2019.2958933S11326

Verifiable Sustainability in Data Centers

Sustainability is crucial for combating climate change and protecting our planet. While there are various systems that can pose a threat to sustainability, data centers are particularly significant due to their substantial energy consumption and environmental impact. Although data centers are becoming increasingly accountable to be sustainable, the current practice of reporting sustainability data is often mired with simple green-washing. To improve this status quo, users as well as regulators need to verify the data on the sustainability impact reported by data center operators. To do so, data centers must have appropriate infrastructures in place that provide the guarantee that the data on sustainability is collected, stored, aggregated, and converted to metrics in a secure, unforgeable, and privacy-preserving manner. Therefore, this paper first introduces the new security challenges related to such infrastructure, how it affects operators and users, and potential solutions and research directions for addressing the challenges for data centers and other industry segments

UnionFS: User- and Communityoriented Development of a Unification Filesystem

Unionfs is a stackable file system that virtually merges a set of directories (called branches) into a single logical view. Each branch is assigned a priority and may be either read-only or read-write. When the highest priority branch is writable, Unionfs provides copy-on-write semantics for read-only branches. These copyon-write semantics have lead to widespread use of Unionfs by LiveCD projects including Knoppix and SLAX. In this paper we describe our experiences distributing and maintaining an out-of-kernel module since November 2004. As of March 2006 Unionfs has been downloaded by over 6,700 unique users and is used by over two dozen other projects. The total number of Unionfs users, by extension, is in the tens of thousands.

Possible Revatio (Sildenafil) Induced Optic Neuropathy in Mice

Purpose: To investigate possible Revatio (sildenafil) induced optic neuropathy in mice

Comparison of corneal surgically induced astigmatism calculations based on keratometry measurements made by 2 biometric devices

PURPOSE: To compare calculated corneal surgically induced astigmatism (SIA) by means of anterior-based keratometry (K) and total keratometry (TK) measurements made by 2 biometric devices. SETTING: Ophthalmology Department, Shaare Zedek Medical Center, Jerusalem, Israel. DESIGN: Retrospective, consecutive case series. METHODS: The medical records of patients who had undergone cataract surgery through a 2.4 mm temporal clear corneal incision by a single surgeon between March 2018 and November 2020 were retrospectively reviewed. Patients for whom there were preoperative and postoperative K measurements assessed by 2 biometric devices, optical low-coherence reflectometry (OLCR) (Lenstar LS900, Haag-Streit, software v. eye suite i/9.1.0.0) and swept-source optical coherence tomography (SS-OCT) (IOLMaster700, Carl Zeiss Meditec AG, software v. 1.80.6.60340), were identified. Corneal SIA (mean vector value) was calculated by vector analysis for 3 groups: SS-OCT(K), SS-OCT(TK), and OLCR(K). Bivariate analyses were applied for comparisons. RESULTS: 147 eyes of 123 patients (73 right eyes and 74 left eyes) were enrolled in the study. The right eye corneal SIA values were 0.09 diopters (D) @ 136 degrees, 0.09 D @ 141 degrees, and 0.07 D @ 123 degrees for the SS-OCT(K), SS-OCT(TK), and OLCR, respectively. The corresponding left eye corneal SIA values were 0.13 D @ 120 degrees, 0.11 D @ 123 degrees, and 0.08 D @ 120 degrees. There were no statistically significant differences between the mean vector value and variance of the corneal SIA for the right (P = .78 and P = .65) and the left (P = .75 and P = .37) eyes of the 3 groups. CONCLUSIONS: Corneal SIA values were low (0.07 to 0.13 D) and similar for the SS-OCT and the OLCR biometric devices with standard K measurements. TK measurements yielded similar corneal SIA values compared with anterior corneal-based measurements

Comparison of corneal surgically induced astigmatism calculations based on keratometry measurements made by 2 biometric devices

PURPOSE: To compare calculated corneal surgically induced astigmatism (SIA) by means of anterior-based keratometry (K) and total keratometry (TK) measurements made by 2 biometric devices. SETTING: Ophthalmology Department, Shaare Zedek Medical Center, Jerusalem, Israel. DESIGN: Retrospective, consecutive case series. METHODS: The medical records of patients who had undergone cataract surgery through a 2.4 mm temporal clear corneal incision by a single surgeon between March 2018 and November 2020 were retrospectively reviewed. Patients for whom there were preoperative and postoperative K measurements assessed by 2 biometric devices, optical low-coherence reflectometry (OLCR) (Lenstar LS900, Haag-Streit, software v. eye suite i/9.1.0.0) and swept-source optical coherence tomography (SS-OCT) (IOLMaster700, Carl Zeiss Meditec AG, software v. 1.80.6.60340), were identified. Corneal SIA (mean vector value) was calculated by vector analysis for 3 groups: SS-OCT(K), SS-OCT(TK), and OLCR(K). Bivariate analyses were applied for comparisons. RESULTS: 147 eyes of 123 patients (73 right eyes and 74 left eyes) were enrolled in the study. The right eye corneal SIA values were 0.09 diopters (D) @ 136 degrees, 0.09 D @ 141 degrees, and 0.07 D @ 123 degrees for the SS-OCT(K), SS-OCT(TK), and OLCR, respectively. The corresponding left eye corneal SIA values were 0.13 D @ 120 degrees, 0.11 D @ 123 degrees, and 0.08 D @ 120 degrees. There were no statistically significant differences between the mean vector value and variance of the corneal SIA for the right (P = .78 and P = .65) and the left (P = .75 and P = .37) eyes of the 3 groups. CONCLUSIONS: Corneal SIA values were low (0.07 to 0.13 D) and similar for the SS-OCT and the OLCR biometric devices with standard K measurements. TK measurements yielded similar corneal SIA values compared with anterior corneal-based measurements

Aberrations of emmetropic subjects at different ages

We made on-axis aberrations and horizontal peripheral refraction measurements of emmetropic subjects (spherical equivalent -0.88 D to +0.75 D) aged between 19 and 70 years. We found smaller changes in on-axis aberrations with age than has previously been reported, possibly because of the small refractive error range of our subject group. Higher order root-mean-squared aberrations increased by 26% across the age range (5 mm pupils), with significant age related changes in 4th- and 6th-order aberrations. The only aberration co-efficient to change significantly was horizontal coma co-efficient C(3, 1). Several aberration co-efficients were significantly different from zero across the group of subjects. The only changes in peripheral refraction with increase in age were shifts in the turning points of the spherical equivalent and horizontal/vertical astigmatism towards less temporal visual field angles