735 research outputs found
Testing the Unitarity of the CKM Matrix with a Space-Based Neutron Decay Experiment
If the Standard Model is correct, and fundamental fermions exist only in the
three generations, then the CKM matrix should be unitary. However, there
remains a question over a deviation from unitarity from the value of the
neutron lifetime. We discuss a simple space-based experiment that, at an orbit
height of 500 km above Earth, would measure the kinetic-energy, solid-angle,
flux spectrum of gravitationally bound neutrons (kinetic energy K<0.606 eV at
this altitude). The difference between the energy spectrum of neutrons that
come up from the Earth's atmosphere and that of the undecayed neutrons that
return back down to the Earth would yield a measurement of the neutron
lifetime. This measurement would be free of the systematics of laboratory
experiments. A package of mass kg could provide a 10^{-3} precision in
two years.Comment: 10 pages, 4 figures. Revised and updated for publicatio
On Collisionless Electron-Ion Temperature Equilibration in the Fast Solar Wind
We explore a mechanism, entirely new to the fast solar wind, of electron
heating by lower hybrid waves to explain the shift to higher charge states
observed in various elements in the fast wind at 1 A.U. relative to the
original coronal hole plasma. This process is a variation on that previously
discussed for two temperature accretion flows by Begelman & Chiueh. Lower
hybrid waves are generated by gyrating minor ions (mainly alpha-particles) and
become significant once strong ion cyclotron heating sets in beyond 1.5 R_sun.
In this way the model avoids conflict with SUMER electron temperature
diagnostic measurements between 1 and 1.5 R_sun. The principal requirement for
such a process to work is the existence of density gradients in the fast solar
wind, with scale length of similar order to the proton inertial length. Similar
size structures have previously been inferred by other authors from radio
scintillation observations and considerations of ion cyclotron wave generation
by global resonant MHD waves.Comment: 32 pages including 11 figures, 4 tables, accepted by Ap
Constructive Field Theory and Applications: Perspectives and Open Problems
In this paper we review many interesting open problems in mathematical
physics which may be attacked with the help of tools from constructive field
theory. They could give work for future mathematical physicists trained with
the constructive methods well within the 21st century
Hyperentangled States
We investigate a new class of entangled states, which we call
'hyperentangled',that have EPR correlations identical to those in the vacuum
state of a relativistic quantum field. We show that whenever hyperentangled
states exist in any quantum theory, they are dense in its state space. We also
give prescriptions for constructing hyperentangled states that involve an
arbitrarily large collection of systems.Comment: 23 pages, LaTeX, Submitted to Physical Review
Structural Information in Two-Dimensional Patterns: Entropy Convergence and Excess Entropy
We develop information-theoretic measures of spatial structure and pattern in
more than one dimension. As is well known, the entropy density of a
two-dimensional configuration can be efficiently and accurately estimated via a
converging sequence of conditional entropies. We show that the manner in which
these conditional entropies converge to their asymptotic value serves as a
measure of global correlation and structure for spatial systems in any
dimension. We compare and contrast entropy-convergence with mutual-information
and structure-factor techniques for quantifying and detecting spatial
structure.Comment: 11 pages, 5 figures,
http://www.santafe.edu/projects/CompMech/papers/2dnnn.htm
Literature-based discovery of diabetes- and ROS-related targets
Abstract Background Reactive oxygen species (ROS) are known mediators of cellular damage in multiple diseases including diabetic complications. Despite its importance, no comprehensive database is currently available for the genes associated with ROS. Methods We present ROS- and diabetes-related targets (genes/proteins) collected from the biomedical literature through a text mining technology. A web-based literature mining tool, SciMiner, was applied to 1,154 biomedical papers indexed with diabetes and ROS by PubMed to identify relevant targets. Over-represented targets in the ROS-diabetes literature were obtained through comparisons against randomly selected literature. The expression levels of nine genes, selected from the top ranked ROS-diabetes set, were measured in the dorsal root ganglia (DRG) of diabetic and non-diabetic DBA/2J mice in order to evaluate the biological relevance of literature-derived targets in the pathogenesis of diabetic neuropathy. Results SciMiner identified 1,026 ROS- and diabetes-related targets from the 1,154 biomedical papers (http://jdrf.neurology.med.umich.edu/ROSDiabetes/). Fifty-three targets were significantly over-represented in the ROS-diabetes literature compared to randomly selected literature. These over-represented targets included well-known members of the oxidative stress response including catalase, the NADPH oxidase family, and the superoxide dismutase family of proteins. Eight of the nine selected genes exhibited significant differential expression between diabetic and non-diabetic mice. For six genes, the direction of expression change in diabetes paralleled enhanced oxidative stress in the DRG. Conclusions Literature mining compiled ROS-diabetes related targets from the biomedical literature and led us to evaluate the biological relevance of selected targets in the pathogenesis of diabetic neuropathy.http://deepblue.lib.umich.edu/bitstream/2027.42/78315/1/1755-8794-3-49.xmlhttp://deepblue.lib.umich.edu/bitstream/2027.42/78315/2/1755-8794-3-49-S7.XLShttp://deepblue.lib.umich.edu/bitstream/2027.42/78315/3/1755-8794-3-49-S10.XLShttp://deepblue.lib.umich.edu/bitstream/2027.42/78315/4/1755-8794-3-49-S8.XLShttp://deepblue.lib.umich.edu/bitstream/2027.42/78315/5/1755-8794-3-49-S3.XLShttp://deepblue.lib.umich.edu/bitstream/2027.42/78315/6/1755-8794-3-49-S1.XLShttp://deepblue.lib.umich.edu/bitstream/2027.42/78315/7/1755-8794-3-49-S4.XLShttp://deepblue.lib.umich.edu/bitstream/2027.42/78315/8/1755-8794-3-49-S2.XLShttp://deepblue.lib.umich.edu/bitstream/2027.42/78315/9/1755-8794-3-49-S12.XLShttp://deepblue.lib.umich.edu/bitstream/2027.42/78315/10/1755-8794-3-49-S11.XLShttp://deepblue.lib.umich.edu/bitstream/2027.42/78315/11/1755-8794-3-49-S9.XLShttp://deepblue.lib.umich.edu/bitstream/2027.42/78315/12/1755-8794-3-49-S5.XLShttp://deepblue.lib.umich.edu/bitstream/2027.42/78315/13/1755-8794-3-49-S6.XLShttp://deepblue.lib.umich.edu/bitstream/2027.42/78315/14/1755-8794-3-49.pdfPeer Reviewe
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