A Search For Star Formation in the Smith Cloud

Motivated by the idea that a subset of HVCs trace dark matter substructure in the Local Group, we search for signs of star formation in the Smith Cloud, a nearby ~2x10^6 Msun HVC currently falling into the Milky Way. Using GALEX NUV and WISE/2MASS NIR photometry, we apply a series of color and apparent magnitude cuts to isolate candidate O and B stars that are plausibly associated with the Smith Cloud. We find an excess of stars along the line of sight to the cloud, but not at a statistically significant level relative to a control region. The number of stars found in projection on the cloud after removing an estimate of the contamination by the Milky Way implies an average star formation rate surface density of 10^(-4.8 +/- 0.3) Msun yr^(-1) kpc^(-2), assuming the cloud has been forming stars at a constant rate since its first passage through the Milky Way ~70 Myr ago. This value is consistent with the star formation rate expected based on the average gas density of the cloud. We also discuss how the newly discovered star forming galaxy Leo P has very similar properties to the Smith Cloud, but its young stellar population would not have been detected at a statistically significant level using our method. Thus, we cannot yet rule out the idea that the Smith Cloud is really a dwarf galaxy.Comment: 9 pages, 7 figures, accepted for publication in MNRA

Birmingham, West Midlands’ Young Persons’ Physical Activity Pathway: Evaluation Report

The Birmingham, West Midlands’ Young Persons’ Physical Activity Pathway (YPPAP) is a pilot six week behavioural intervention (a physical activity pathway) aimed at increasing physical activity levels in school-aged children in school years 6 and 7 (ages 10-12 yrs). It builds on the experiences of the South Staffordshire (SS) Physical Activity Care Pathway (PACP), but was developed specifically to focus on school-age young people in an urban city setting. For the purposes of the evaluation a mixed-methods approach including a quantitative and qualitative component was employed. Data analysis revealed that of the 239 eligible participants, 99 entered the pathway (31.2%). Ninety-three participants set physical goals at baseline and 3 were lost to follow up representing a pathway completion rate of 97% (n = 90). Overall, the results indicated that the increase in ‘spare time’ physical activity was statistically significant (t(95)=-2.88, p=.005), but the differences were not significant for overall physical activity (t(95)=-.096, p=.924), or mean frequency of physical activity (t(95)=-.414, p=.680). Analysis also revealed that the correlation between change in physical activity between baseline and follow up and the number of goals set by participants was not significant (r = 0.08, p =.436). Qualitative findings revealed that participants perceived that the pathway had helped to educate them about the relationship between physical activity and health and had provided a means of engaging with physical activity in a way that was fun and non-threatening. Delivery costs were also calculated taking into account management and delivery costs, including resources, training and support, the total cost per child of delivering the intervention was £143. The high completion rate might point to the utility of using school settings for physical activity interventions. Problematically, the limited sample size prevented the meaningful investigation of any relationship between the physical activity options chosen by young participants and outcomes in terms of potential increases in levels of physical activity. Similarly, it was not possible to fully investigate the potential effects of gender, class, ethnicity, disability status on adherence to the pathway or physical activity behaviour. More usefully, data analysis revealed that the pathway attracted a range of participants which demonstrated potential for securing the interest and motivation of participants. This finding underpins the importance of understanding the number, variety and availability of local physical activity opportunities and delivering the intervention in a way that is engaging and supportive

Texas Forestry Paper No. 26

Aerial photograph use in industrial forest management in the south, 1970 and 1974https://scholarworks.sfasu.edu/texas_forestry_papers/1014/thumbnail.jp

Mitochondrial DNA and temperature tolerance in lager yeasts

A growing body of research suggests that the mitochondrial genome (mtDNA) is important for temperature adaptation. In the yeast genus Saccharomyces, species have diverged in temperature tolerance, driving their use in high- or low-temperature fermentations. Here, we experimentally test the role of mtDNA in temperature tolerance in synthetic and industrial hybrids (Saccharomyces cerevisiae × Saccharomyces eubayanus or Saccharomyces pastorianus), which cold-brew lager beer. We find that the relative temperature tolerances of hybrids correspond to the parent donating mtDNA, allowing us to modulate lager strain temperature preferences. The strong influence of mitotype on the temperature tolerance of otherwise identical hybrid strains provides support for the mitochondrial climactic adaptation hypothesis in yeasts and demonstrates how mitotype has influenced the world’s most commonly fermented beverage.This work was supported by the USDA National Institute of Food and Agriculture (Hatch project no. 1003258), the NSF (grant no. DEB-1253634), and in part by the DOE Great Lakes Bioenergy Research Center (DOE BER Office of Science; nos. DE-SC0018409 and DE-FC02-07ER64494). E.P.B. was supported by a Louis and Elsa Thomsen Wisconsin Distinguished Graduate Fellowship. C.T.H. is a Pew Scholar in the Biomedical Sciences and a Vilas Faculty Early Career Investigator, supported by the Pew Charitable Trusts and the Vilas Trust Estate. D.P. is a Marie Sklodowska-Curie fellow of the European Union’s Horizon 2020 research and innovation programme (grant agreement no. 747775). J.C.F. was supported by the NIH (no. GM080669)Peer Reviewe

The Fueling Diagram: Linking Galaxy Molecular-to-Atomic Gas Ratios to Interactions and Accretion

To assess how external factors such as local interactions and fresh gas accretion influence the global ISM of galaxies, we analyze the relationship between recent enhancements of central star formation and total molecular-to-atomic (H2/HI) gas ratios, using a broad sample of field galaxies spanning early-to-late type morphologies, stellar masses of 10^(7.2-11.2) Msun, and diverse stages of evolution. We find that galaxies occupy several loci in a "fueling diagram" that plots H2/HI vs. mass-corrected blue-centeredness, a metric tracing the degree to which galaxies have bluer centers than the average galaxy at their stellar mass. Spiral galaxies show a positive correlation between H2/HI and mass-corrected blue-centeredness. When combined with previous results linking mass-corrected blue-centeredness to external perturbations, this correlation suggests a link between local galaxy interactions and molecular gas inflow/replenishment. Intriguingly, E/S0 galaxies show a more complex picture: some follow the same correlation, some are quenched, and a distinct population of blue-sequence E/S0 galaxies (with masses below key transitions in gas richness) defines a separate loop in the fueling diagram. This population appears to be composed of low-mass merger remnants currently in late- or post-starburst states, in which the burst first consumes the H2 while the galaxy center keeps getting bluer, then exhausts the H2, at which point the burst population reddens as it ages. Multiple lines of evidence suggest connected evolutionary sequences in the fueling diagram. In particular, tracking total gas-to-stellar mass ratios within the diagram provides evidence of fresh gas accretion onto low-mass E/S0s emerging from central starbursts. Drawing on a comprehensive literature search, we suggest that virtually all galaxies follow the same evolutionary patterns found in our broad sample.Comment: 24 pages, 11 figures (table 4 available at http://user.physics.unc.edu/~dstark/table4_csv.txt), accepted for publication in Ap

Protein–DNA binding specificity predictions with structural models

Protein–DNA interactions play a central role in transcriptional regulation and other biological processes. Investigating the mechanism of binding affinity and specificity in protein–DNA complexes is thus an important goal. Here we develop a simple physical energy function, which uses electrostatics, solvation, hydrogen bonds and atom-packing terms to model direct readout and sequence-specific DNA conformational energy to model indirect readout of DNA sequence by the bound protein. The predictive capability of the model is tested against another model based only on the knowledge of the consensus sequence and the number of contacts between amino acids and DNA bases. Both models are used to carry out predictions of protein–DNA binding affinities which are then compared with experimental measurements. The nearly additive nature of protein–DNA interaction energies in our model allows us to construct position-specific weight matrices by computing base pair probabilities independently for each position in the binding site. Our approach is less data intensive than knowledge-based models of protein–DNA interactions, and is not limited to any specific family of transcription factors. However, native structures of protein–DNA complexes or their close homologs are required as input to the model. Use of homology modeling can significantly increase the extent of our approach, making it a useful tool for studying regulatory pathways in many organisms and cell types

Birmingham, West Midlands’ Young Persons’ Physical Activity Pathway: Evaluation Report

The Birmingham, West Midlands’ Young Persons’ Physical Activity Pathway (YPPAP) is a pilot six week behavioural intervention (a physical activity pathway) aimed at increasing physical activity levels in school-aged children in school years 6 and 7 (ages 10-12 yrs). It builds on the experiences of the South Staffordshire (SS) Physical Activity Care Pathway (PACP), but was developed specifically to focus on school-age young people in an urban city setting. For the purposes of the evaluation a mixed-methods approach including a quantitative and qualitative component was employed. Data analysis revealed that of the 239 eligible participants, 99 entered the pathway (31.2%). Ninety-three participants set physical goals at baseline and 3 were lost to follow up representing a pathway completion rate of 97% (n = 90). Overall, the results indicated that the increase in ‘spare time’ physical activity was statistically significant (t(95)=-2.88, p=.005), but the differences were not significant for overall physical activity (t(95)=-.096, p=.924), or mean frequency of physical activity (t(95)=-.414, p=.680). Analysis also revealed that the correlation between change in physical activity between baseline and follow up and the number of goals set by participants was not significant (r = 0.08, p =.436). Qualitative findings revealed that participants perceived that the pathway had helped to educate them about the relationship between physical activity and health and had provided a means of engaging with physical activity in a way that was fun and non-threatening. Delivery costs were also calculated taking into account management and delivery costs, including resources, training and support, the total cost per child of delivering the intervention was £143. The high completion rate might point to the utility of using school settings for physical activity interventions. Problematically, the limited sample size prevented the meaningful investigation of any relationship between the physical activity options chosen by young participants and outcomes in terms of potential increases in levels of physical activity. Similarly, it was not possible to fully investigate the potential effects of gender, class, ethnicity, disability status on adherence to the pathway or physical activity behaviour. More usefully, data analysis revealed that the pathway attracted a range of participants which demonstrated potential for securing the interest and motivation of participants. This finding underpins the importance of understanding the number, variety and availability of local physical activity opportunities and delivering the intervention in a way that is engaging and supportive

Landscape-scale responses of birds to agri-environment management: a test of the English Environmental Stewardship scheme

1. Agri-environment schemes (AES) are used extensively across Europe to address biodiversity declines in farmland. In England, Environmental Stewardship (ES) was introduced in 2005 to address the shortcomings of previous schemes, but as for schemes in other countries, assessments to date have revealed little evidence for national-scale biodiversity benefits. 2. Here, we assess the efficacy of ES in driving changes in national farmland bird populations over the period 2002–2010, using BTO/JNCC/RSPB Breeding Bird Survey data. We tested for associations between ES management options, grouped into categories reflecting intended biological effects (e.g. stubble), and species’ population growth rates, wherever benefits of management might be expected to occur. 3. We found strong evidence for positive effects of management that provides winter food resources (i.e. ES stubble and wild bird seed [WBS] crops) on population growth rates across multiple granivorous species, at three landscape scales. The results for management aiming to provide breeding season benefits (i.e. grassland, field margin and boundary [hedge, ditch] management) showed mixed patterns of positive and negative associations. 4. The results for stubble and WBS provide the first evidence for landscape-scale responses of biodiversity to AES management. The negative relationships identified may also show the importance of management context driving unforeseen predation or competition effects. 5. Synthesis and Applications. This study demonstrates that agri-environment scheme management has the potential to have national-scale effects on avian population growth rates, although our results suggest that some components of the scheme have had little effect on bird populations. Therefore, whilst this study provides the first proof-of-concept for broad-and-shallow scheme impacts on biodiversity, our results underline the importance of targeting towards population-limiting factors, here winter food resources. A combination of low uptake of key in-field options that provide winter seed and a failure to cover the late-winter period effectively explains the lack of national population responses. Such issues need to be addressed before schemes like Environmental Stewardship will achieve their goals. This study shows the value of feedback from monitoring for informing scheme design, through identifying problems and testing solutions