288 research outputs found
Revealing Compressed Stops Using High-Momentum Recoils
Searches for supersymmetric top quarks at the LHC have been making great
progress in pushing sensitivity out to higher mass, but are famously plagued by
gaps in coverage around lower-mass regions where the decay phase space is
closing off. Within the common stop-NLSP / neutralino-LSP simplified model, the
line in the mass plane where there is just enough phase space to produce an
on-shell top quark remains almost completely unconstrained. Here, we show that
is possible to define searches capable of probing a large patch of this
difficult region, with S/B ~ 1 and significances often well beyond 5 sigma. The
basic strategy is to leverage the large energy gain of LHC Run 2, leading to a
sizable population of stop pair events recoiling against a hard jet. The recoil
not only re-establishes a MET signature, but also leads to a distinctive
anti-correlation between the MET and the recoil jet transverse vectors when the
stops decay all-hadronically. Accounting for jet combinatorics, backgrounds,
and imperfections in MET measurements, we estimate that Run 2 will already
start to close the gap in exclusion sensitivity with the first few 10s of
inverse-fb. By 300/fb, exclusion sensitivity may extend from stop masses of 550
GeV on the high side down to below 200 GeV on the low side, approaching the
"stealth" point at m(stop) = m(top) and potentially overlapping with limits
from top pair cross section and spin correlation measurements.Comment: 17 pages, 6 figure
Management and incomes policy
The difficulty of achieving Britain's economic objectives has resulted in successive governments searching for a new and effective economic tool to use in addition to existing fiscal and monetary policies. This instrument could be the prices and incomes policy which has been evolved in an attempt to solve the problem persisting in many developed economies; that of controlling the growth of inflation while maintaining full employment.While the national leaders of employers federations and trade unions have expressed their views on the policy, little is known about the views of practicing managers and rank and file trade unionists, ie. the men involved in actually imp- lementing the policy. This study attempted to bridge part of this gap and sought to discover the extent of managers' understanding of and their opinions on many features of the prices and incomes policy. The report was based on a survey of the opinions of 270 senior managers engaged in a wide range of manufacturing industries.The most general finding was that the respondents' know- ledge of the prices and incomes policy was somewhat limited. Despite the imperfect understanding of both the policy and its aims, considerable support existed for such a measure.
The managers with a greater degree of comprehension of Britain's economic difficulties and the prices and incomes policy were, however, more inclined to support the policy than those with a lower level of understanding. To examine this finding more closely a study was made of environmental factors which could have affected the respondents° knowledge of the policy with a view to discovering means of raising managements' apparent low level of understanding of economic affairs.It was also discovered that the majority of the respond- ents believed that a prices and incomes policy had a role to play in Britain's economic future. Opinion, however, was di- vided over the issue of whether the policy should be a permanent feature of economic policy or used only as an in- strument of control at times of crisis. To enhance the pro- spects of the policy's success most of the respondents thought that the Government would have to use powers of compulsion.Information was also obtained about the respondents' views on a second role for the policy as an arbiter of social justice in determining the relative level of incomes. This facet of the policy also received general approval.The overall conclusion of this research is that Govern- ment and management should be more fully aware of each other's
views. This, it would seem, would lay the foundations of a deeper understanding on both sides and increase the managers' willingness to co-operate with the Government
Setting a Global Standard: The Case for Accounting Convergence
As capital markets play an increasingly central role in today\u27s modern economies, policy-makers are confronted with the question of how to assure the continued effective functioning of these markets and, in particular, how to develop a sound financial reporting infrastructure. Recent experience suggests that such a reporting infrastructure must be built on accounting standards that are consistent, comprehensive, and based on clear principles to enable financial reports to reflect underlying economic reality
Setting a Global Standard: The Case for Accounting Convergence
As capital markets play an increasingly central role in today\u27s modern economies, policy-makers are confronted with the question of how to assure the continued effective functioning of these markets and, in particular, how to develop a sound financial reporting infrastructure. Recent experience suggests that such a reporting infrastructure must be built on accounting standards that are consistent, comprehensive, and based on clear principles to enable financial reports to reflect underlying economic reality
Warped Supersymmetric Unification with Non-Unified Superparticle Spectrum
We present a new supersymmetric extension of the standard model. The model is
constructed in warped space, with a unified bulk symmetry broken by boundary
conditions on both the Planck and TeV branes. In the supersymmetric limit, the
massless spectrum contains exotic colored particles along with the particle
content of the minimal supersymmetric standard model (MSSM). Nevertheless, the
model still reproduces the MSSM prediction for gauge coupling unification and
does not suffer from a proton decay problem. The exotic states acquire masses
from supersymmetry breaking, making the model completely viable, but there is
still the possibility that these states will be detected at the LHC. The
lightest of these states is most likely A_5^XY, the fifth component of the
gauge field associated with the broken unified symmetry. Because supersymmetry
is broken on the SU(5)-violating TeV brane, the gaugino masses generated at the
TeV scale are completely independent of one another. We explore some of the
unusual features that the superparticle spectrum might have as a consequence.Comment: 21 pages, Latex, version to appear in Phys. Rev.
Top-tagging: A Method for Identifying Boosted Hadronic Tops
A method is introduced for distinguishing top jets (boosted, hadronically
decaying top quarks) from light quark and gluon jets using jet substructure.
The procedure involves parsing the jet cluster to resolve its subjets, and then
imposing kinematic constraints. With this method, light quark or gluon jets
with pT ~ 1 TeV can be rejected with an efficiency of around 99% while
retaining up to 40% of top jets. This reduces the dijet background to heavy
t-tbar resonances by a factor of ~10,000, thereby allowing resonance searches
in t-tbar to be extended into the all-hadronic channel. In addition,
top-tagging can be used in t-tbar events when one of the tops decays
semi-leptonically, in events with missing energy, and in studies of b-tagging
efficiency at high pT.Comment: 4 pages, 4 figures; v2: separate quark and gluon efficiencies
included, figure on helicity angle added, and physics discussion extende
Arctic Tundra Vegetation Functional Types Based on Photosynthetic Physiology and Optical Properties
Climate change in tundra regions may alter vegetation species composition and ecosystem carbon balance. Remote sensing provides critical tools for monitoring these changes as optical signals provide a way to scale from plot measurements to regional patterns. Gas exchange measurements of pure patches of key vegetation functional types (lichens, mosses, and vascular plants) in sedge tundra at Barrow AK, show three significantly different values of light use efficiency (LUE) with values of 0.013+/-0.001, 0.0018+/-0.0002, and 0.0012 0.0001 mol C/mol absorbed quanta for vascular plants, mosses and lichens, respectively. Further, discriminant analysis of patch reflectance identifies five spectral bands that can separate each vegetation functional type as well as nongreen material (bare soil, standing water, and dead leaves). These results were tested along a 100 m transect where midsummer spectral reflectance and vegetation coverage were measured at one meter intervals. Area-averaged canopy LUE estimated from coverage fractions of the three functional types varied widely, even over short distances. Patch-level statistical discriminant functions applied to in situ hyperspectral reflectance successfully unmixed cover fractions of the vegetation functional types. These functions, developed from the tram data, were applied to 30 m spatial resolution Earth Observing-1 Hyperion imaging spectrometer data to examine regional variability in distribution of the vegetation functional types and from those distributions, the variability of LUE. Across the landscape, there was a fivefold variation in tundra LUE that was correlated to a spectral vegetation index developed to detect vegetation chlorophyll content
Thalidomide Analogues Suppress Lipopolysaccharide-Induced Synthesis of TNF-α and Nitrite, an Intermediate of Nitric Oxide, in a Cellular Model of Inflammation
An unregulated neuroinflammation accompanies numerous chronic and acute neurodegenerative disorders and it is postulated that such a neuroinflammatory component likely exacerbates disease progression. A key player in brain inflammation is the microglial cell; a vital soluble factor synthesized by activated microglial cells is the key cytokine, tumor necrosis factor–alpha (TNF-α). Additionally, microglial cells release IL-1α/β, reactive oxygen species (ROS), such as superoxide (O2-) and reactive nitrogen species (RNS) like nitric oxide (NO). Nitric oxide reactive oxygen species can undergo various forms of interactions in cells whereby the synthesis of RNS / ROS intermediates are generated that can damage cell membranes. The presence of oxidative damaged cells is implicated with the abnormal cellular activity in brain or in the spinal cord, and is a classical feature of neurodegenerative disorders. To aid characterize this process, a quantitative analysis of nitrite generation was undertaken on agents developed to lower TNF-α levels in cell culture. Nitrite is a stable end product of nitric oxide metabolism and, thereby, acts as a surrogate measure of the highly unstable nitric oxide. Utilizing a RAW 264.7 cellular model of lipopolysaccharide-induced inflammation that induces high levels of TNF-α protein accompanied by a robust generation of nitrite, the properties of a series of thalidomide-based TNF-α synthesis inhibitors were evaluated to reduce the levels of both. Specific analogues of thalidomide effectively suppressed the generation of both TNF-α and nitrite at well-tolerated doses
TNF-α protein synthesis inhibitor restores neuronal function and reverses cognitive deficits induced by chronic neuroinflammation
Abstract Background Chronic neuroinflammation is a hallmark of several neurological disorders associated with cognitive loss. Activated microglia and secreted factors such as tumor necrosis factor (TNF)-α are key mediators of neuroinflammation and may contribute to neuronal dysfunction. Our study was aimed to evaluate the therapeutic potential of a novel analog of thalidomide, 3,6'-dithiothalidomide (DT), an agent with anti-TNF-α activity, in a model of chronic neuroinflammation. Methods Lipopolysaccharide or artificial cerebrospinal fluid was infused into the fourth ventricle of three-month-old rats for 28 days. Starting on day 29, animals received daily intraperitoneal injections of DT (56 mg/kg/day) or vehicle for 14 days. Thereafter, cognitive function was assessed by novel object recognition, novel place recognition and Morris water maze, and animals were euthanized 25 min following water maze probe test evaluation. Results Chronic LPS-infusion was characterized by increased gene expression of the proinflammatory cytokines TNF-α and IL-1β in the hippocampus. Treatment with DT normalized TNF-α levels back to control levels but not IL-1β. Treatment with DT attenuated the expression of TLR2, TLR4, IRAK1 and Hmgb1, all genes involved in the TLR-mediated signaling pathway associated with classical microglia activation. However DT did not impact the numbers of MHC Class II immunoreactive cells. Chronic neuroinflammation impaired novel place recognition, spatial learning and memory function; but it did not impact novel object recognition. Importantly, treatment with DT restored cognitive function in LPS-infused animals and normalized the fraction of hippocampal neurons expressing the plasticity-related immediate-early gene Arc. Conclusion Our data demonstrate that the TNF-α synthesis inhibitor DT can significantly reverse hippocampus-dependent cognitive deficits induced by chronic neuroinflammation. These results suggest that TNF-α is a critical mediator of chronic neuroinflammation-induced neuronal dysfunction and cognitive impairment and targeting its synthesis could provide an effective therapeutic approach to several human neurodegenerative diseases
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