Additional file 1: of Network-based analysis of transcriptional profiles from chemical perturbations experiments

Supplementary Figures. Additional figures with supplementary results. (PDF 1229 kb

Additional file 4: Table S3. of Network-based analysis of transcriptional profiles from chemical perturbations experiments

Aggregate Network-related modules with connectivity specifically altered by compound groups. (XLSX 12 kb

Catalpa bignonioides Walt.

原著和名: アメリカキササゲ科名: ノウゼンカズラ科 = Bignoniaceae採集地: 千葉県 千葉市 千葉大学 (下総 千葉市 千葉大学)採集日: 1979/6/15採集者: 萩庭丈壽整理番号: JH026901国立科学博物館整理番号: TNS-VS-97690

Grewia rhombifolia Kanehira et Sasaki

原著和名: ウヲトリギ エノキウツギ科名: シナノキ科 = Tiliaceae採集地: 千葉県 千葉市 (下総 千葉市)採集日: 1964/7/1採集者: 萩庭丈壽整理番号: JH026860国立科学博物館整理番号: TNS-VS-97686

Additional file 2: of A network based approach to drug repositioning identifies plausible candidates for breast cancer and prostate cancer

and 2–1 show detailed process of MP score computation. (DOCX 106 kb

Additional file 4: of A network based approach to drug repositioning identifies plausible candidates for breast cancer and prostate cancer

shows detailed description of identified drug candidates for breast and prostate cancer. (XLSX 140 kb

Additional file 11: Figure S6. of A network based approach to drug repositioning identifies plausible candidates for breast cancer and prostate cancer

Titration curves of cell viability under treatment of Fluphenazine. Viability of MCF10A, MCF7 and SUM 149 cells exposed to Fluphenazine with concentrations ranging from 3.125 μM to 100 μM after 24 h incubation. The relative viability was calculated as relative viability = (experimental absorbance - background absorbance)/ (absorbance of untreated controls - background absorbance of untreated controls) × 100 % (means ± SD, n = 3). (PPTX 55 kb

The successful strategic plans

Strategic planning is a very suitable method to effectively manage long-term development of the area. A lot of strategic documents have been made in recent years. There are strategic plans of counties, micro-regions, towns, even larger villages, but unfortunately they are not realized. The aim of my work is not to find out why most of the strategic plans are unsuccessful, but why chosen towns (Dobříš and Vodňany) are such successful in realization of the plans. The information about the process of the strategic planning was acquired from the formal interviews with the processors of the strategic plans, with the mayor or deputy mayor of both towns. There is described the whole process of the strategic planning, from the initial idea to prepare strategic plan until the process of creating the plan, its evaluation, monitoring and updating. Text is supplemented with the ideas and insights of processors, mayors, deputy mayors and authors of a literature dealing with the topic. At the very end are summarized main reasons why strategic planning of these cities successful. Keywords: strategic plannig, city, community method of plannin

Additional file 7: of The role of the aryl hydrocarbon receptor in the development of cells with the molecular and functional characteristics of cancer stem-like cells

The data sets supporting the results of each of the figures in this article are included within this excel document. For further information, please contact the corresponding author. (XLSX 81 kb

Additional file 3: Figure S1. of Dioxins and related environmental contaminants increase TDP-43 levels

Elevation of endogenous TDP-43 is dependent upon AHR expression. Figure S2. The effect on TDP-43 protein levels in the brain of peripheral exposure to AHR agonists is not observed with other disease related proteins. Figure S3. TARDBP promoter is activated by AHR agonism. Figure S4. Click-iT pulse-chase labelling of nascent proteins in differentiated M17 cells. Figure S5. Schematic representation of sense AHRE consensus sites “GCGTG” (red flags) of human CYP1A1 and CYP1B1 AHR responsive genes and the ALS-relevant genes TARDBP, SOD1, PON2, C9ORF72, FUS and ATXN2, assayed for changes in transcript levels in Fig. 2. Green boxes are exons. (PDF 2754 kb