Outflows in Infrared-Luminous Starbursts at z < 0.5. II. Analysis and Discussion

We have performed an absorption-line survey of outflowing gas in 78 starburst-dominated, infrared-luminous galaxies. This is the largest study of superwinds at z < 3. Superwinds are found in almost all infrared-luminous galaxies, and changes in detection rate with SFR--winds are found twice as often in ultraluminous infrared galaxies (ULIRGs) as in less-luminous galaxies--reflect different wind geometries. The maximum velocities we measure are 600 km/s, though most of the outflowing gas has lower velocities (100-200 km/s). (One galaxy has velocities exceeding 1000 km/s.) Velocities in LINERs are higher than in HII galaxies, and outflowing ionized gas often has higher velocities than the neutral gas. Wind properties (velocity, mass, momentum, and energy) scale with galaxy properties (SFR, luminosity, and galaxy mass), consistent with ram-pressure driving of the wind. Wind properties increase strongly with increasing galactic mass, contrary to expectation. These correlations flatten at high SFR (> 10-100 M_sun/yr), luminosities, and masses. This saturation is due to a lack of gas remaining in the wind's path, a common neutral gas terminal velocity, and/or a decrease in the efficiency of thermalization of the supernovae energy. It means that mass entrainment efficiency, rather than remaining constant, declines in galaxies with SFR > 10 M_sun/yr and M_K < -24. Half of our sample consists of ULIRGs, which host as much as half of the star formation in the universe at z > 1. The powerful, ubiquitous winds we observe in these galaxies imply that superwinds in massive galaxies at redshifts above unity play an important role in the evolution of galaxies and the intergalactic medium.Comment: 68 pages, 20 figures in AASTeX preprint style; to appear in September issue of ApJS; Figure 17 replaced with correct versio

Review of Recent Searches for Rare and Forbidden Dilepton Decays of Charmed Mesons

I briefly review the results of recent searches for flavor-changing neutral current and lepton-flavor and lepton-number violating decays of D+, Ds, and D0 mesons (and their antiparticles) into modes containing muons and electrons. The primary focus is the results from Fermilab charm hadroproduction experiment E791. E791 examined 24 pi,l,l and K,l,l decay modes of D+ and Ds and l+l- decay modes of D0. Limits presented by E791 for 22 rare and forbidden dilepton decays of D mesons were more stringent than those obtained from previous searches, or else were the first reported.Comment: 8 pages, 1 figure, uses psfig.sty and RevTeX, submitted to Modern Physics Letters A, based on a Fermilab "Joint Theoretical and Experimental" tal

Measuring progess on diet-related NCD's: the need to address the causes of the causes

WHO has developed nine voluntary global monitoring targets and 25 indicators to assess progress in the implementation of national strategies to achieve the global political commitment to reduce the probability of dying from non-communicable diseases (NCDs) for people aged 30–70 years, by 25% by 2025.1,2 Robert Beaglehole and colleagues (Oct 13, p 1283)3 argue that it is better to focus on two of the population-wide targets: tobacco control and dietary salt reduction, and the treatment target, and that the targets should be reported according to socioeconomic status and gender.Department of HE and Training approved lis

Elliptical Galaxy in the Making: The Dual Active Galactic Nuclei and Metal-enriched Halo of Mrk 273

A systematic analysis of the X-ray emission from the nearby ultraluminous infrared galaxy Mrk 273 was carried out by combining new 200 ksec Chandra data with archived 44 ksec data. The active galactic nucleus (AGN) associated with the Southwest nucleus is confirmed by the new data, and a secondary hard X-ray (4-8 keV) point source is detected, coincident with the Northeast nucleus at a projected distance of 0.75 kpc from the Southwest nucleus. The hard X-ray spectrum of the Northeast nucleus is consistent with a heavily absorbed AGN, making Mrk 273 another example of a dual AGN in a nearby galaxy merger. Significant 1-3 keV emission is found along the ionization cones and outflowing gas detected in a previous study. The data also map the giant X-ray nebula south of the host galaxy with unprecedented detail. This nebula extends on a scale of $\sim$ 40 kpc $\times$ 40 kpc, and is not closely related to the well-known tidal tail seen in the optical. The X-ray emission of the nebula is best described by a single-temperature gas model, with a temperature of $\sim$ 7 million K and a super-solar $\alpha$/Fe ratio. Further analysis suggests that the southern nebula has most likely been heated and enriched by multiple galactic outflows generated by the AGN and/or circumnuclear starburst in the past, on a time scale of $\lesssim$0.1 Gyr, similar to the merger event itself.Comment: 25 pages, 22 figures, 4 tables, accepted for publication in the Astrophysical Journa

SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation

Many enveloped viruses induce multinucleated cells (syncytia), reflective of membrane fusion events caused by the same machinery that underlies viral entry. These syncytia are thought to facilitate replication and evasion of the host immune response. Here, we report that co-culture of human cells expressing the receptor ACE2 with cells expressing SARS-CoV-2 spike, results in synapse-like intercellular contacts that initiate cell-cell fusion, producing syncytia resembling those we identify in lungs of COVID-19 patients. To assess the mechanism of spike/ACE2-driven membrane fusion, we developed a microscopy-based, cell-cell fusion assay to screen ~6000 drugs and \u3e30 spike variants. Together with quantitative cell biology approaches, the screen reveals an essential role for biophysical aspects of the membrane, particularly cholesterol-rich regions, in spike-mediated fusion, which extends to replication-competent SARS-CoV-2 isolates. Our findings potentially provide a molecular basis for positive outcomes reported in COVID-19 patients taking statins and suggest new strategies for therapeutics targeting the membrane of SARS-CoV-2 and other fusogenic viruses

Outflows in Infrared-Luminous Starbursts at z < 0.5. I. Sample, NaI D Spectra, and Profile Fitting

We have conducted a spectroscopic survey of 78 starbursting infrared-luminous galaxies at redshifts up to z = 0.5. We use moderate-resolution spectroscopy of the NaI D interstellar absorption feature to directly probe the neutral phase of outflowing gas in these galaxies. Over half of our sample are ultraluminous infrared galaxies that are classified as starbursts; the rest have infrared luminosities in the range log(L_IR/L_sun) = 10.2 - 12.0. The sample selection, observations, and data reduction are described here. The absorption-line spectra of each galaxy are presented. We also discuss the theory behind absorption-line fitting in the case of a partially-covered, blended absorption doublet observed at moderate-to-high resolution, a topic neglected in the literature. A detailed analysis of these data is presented in a companion paper.Comment: 59 pages, 18 figures in AASTeX preprint style; to appear in September issue of ApJ