2,609 research outputs found
A Proposed Form for Local Board Consideration of Conscientious Objector Claims
The general subject of selective service reform contains enough problems to busy the proverbial thousand monkeys at a thousand typewriters for a thousand years in an effort to solve just one. A solution to one of these problems, conscientious objection, would surely justify the effort. But this article, being the work of a single man using a single typewriter over a period considerably less than a year, makes no such pretense. Unlike most of the books, articles, and commission reports dealing with the selective service law, and conscientious objection in particular, this article is concerned primarily with procedural rather than substantive issues. It is a plea for an administratively imposed requirement that a standard form be used by local boards in considering conscientious objector claims
A Review of High School Level Astronomy Student Research Projects over the last two decades
Since the early 1990s with the arrival of a variety of new technologies, the
capacity for authentic astronomical research at the high school level has
skyrocketed. This potential, however, has not realized the bright-eyed hopes
and dreams of the early pioneers who expected to revolutionise science
education through the use of telescopes and other astronomical instrumentation
in the classroom. In this paper, a general history and analysis of these
attempts is presented. We define what we classify as an Astronomy Research in
the Classroom (ARiC) project and note the major dimensions on which these
projects differ before describing the 22 major student research projects active
since the early 1990s. This is followed by a discussion of the major issues
identified that affected the success of these projects and provide suggestions
for similar attempts in the future.Comment: Accepted for Publication in PASA. 26 page
The planetary nebula Abell 48 and its [WN] nucleus
We have conducted a detailed multi-wavelength study of the peculiar nebula
Abell 48 and its central star. We classify the nucleus as a helium-rich,
hydrogen-deficient star of type [WN4-5]. The evidence for either a massive WN
or a low-mass [WN] interpretation is critically examined, and we firmly
conclude that Abell 48 is a planetary nebula (PN) around an evolved low-mass
star, rather than a Population I ejecta nebula. Importantly, the surrounding
nebula has a morphology typical of PNe, and is not enriched in nitrogen, and
thus not the `peeled atmosphere' of a massive star. We estimate a distance of
1.6 kpc and a reddening, E(B-V) = 1.90 mag, the latter value clearly showing
the nebula lies on the near side of the Galactic bar, and cannot be a massive
WN star. The ionized mass (~0.3 M_Sun) and electron density (700 cm^-3) are
typical of middle-aged PNe. The observed stellar spectrum was compared to a
grid of models from the Potsdam Wolf-Rayet (PoWR) grid. The best fit
temperature is 71 kK, and the atmospheric composition is dominated by helium
with an upper limit on the hydrogen abundance of 10 per cent. Our results are
in very good agreement with the recent study of Todt et al., who determined a
hydrogen fraction of 10 per cent and an unusually large nitrogen fraction of ~5
per cent. This fraction is higher than any other low-mass H-deficient star, and
is not readily explained by current post-AGB models. We give a discussion of
the implications of this discovery for the late-stage evolution of
intermediate-mass stars. There is now tentative evidence for two distinct
helium-dominated post-AGB lineages, separate to the helium and carbon dominated
surface compositions produced by a late thermal pulse. Further theoretical work
is needed to explain these recent discoveries.Comment: 19 pages, 10 figures, to appear in MNRAS. Version 3 incorporates
proof correction
Resume of David M. Fitzgerald, 1992-02
Naval Postgraduate School Faculty Resum
Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration
Brain aging is associated with diminished circadian clock output and decreased expression of the core clock proteins, which regulate many aspects of cellular biochemistry and metabolism. The genes encoding clock proteins are expressed throughout the brain, though it is unknown whether these proteins modulate brain homeostasis. We observed that deletion of circadian clock transcriptional activators aryl hydrocarbon receptor nuclear translocator-like (Bmal1) alone, or circadian locomotor output cycles kaput (Clock) in combination with neuronal PAS domain protein 2 (Npas2), induced severe age-dependent astrogliosis in the cortex and hippocampus. Mice lacking the clock gene repressors period circadian clock 1 (Per1) and period circadian clock 2 (Per2) had no observed astrogliosis. Bmal1 deletion caused the degeneration of synaptic terminals and impaired cortical functional connectivity, as well as neuronal oxidative damage and impaired expression of several redox defense genes. Targeted deletion of Bmal1 in neurons and glia caused similar neuropathology, despite the retention of intact circadian behavioral and sleep-wake rhythms. Reduction of Bmal1 expression promoted neuronal death in primary cultures and in mice treated with a chemical inducer of oxidative injury and striatal neurodegeneration. Our findings indicate that BMAL1 in a complex with CLOCK or NPAS2 regulates cerebral redox homeostasis and connects impaired clock gene function to neurodegeneration
Development and validation of an astronomy self-efficacy instrument for understanding and doing
This paper presents a new astronomy self-efficacy instrument, composed of two factors; one relating to learning astronomy content, which we call astronomy personal self-efficacy, and the other relating to the use of astronomical instrumentation, specifically the use of remote robotic telescopes for data collection. The latter is referred to as the astronomy instrumental self-efficacy factor. The instrument has been tested for reliability and construct validity. Reliability testing showed that factor 1 had a Cronbach\u27s α of 0.901 and factor 2 had a Cronbach\u27s α of 0.937. Construct validity was established by computing one-way analyses of variances, with the p value suitably protected, using independent variables peripherally related to the constructs. These analyses demonstrate that both scales possess high construct validity. The development of this astronomy specific instrument is an important step in evaluating self-efficacy as a precursor to investigating the construct of science identity in the field of astronomy
Confirmatory factor analysis of two self-efficacy scales for astronomy understanding and robotic telescope use
This paper presents the results of a confirmatory factor analysis on two self-efficacy scales designed to probe the self-efficacy of college-level introductory astronomy (Astro-101) students (n=15181) from 22 institutions across the United States of America and Canada. The students undertook a course based on similar curriculum materials, which involved students using robotic telescopes to support their learning of astronomical concepts covered in the traditional Astro-101 courses. Previous research by the authors using these self-efficacy scales within a pre-/post-test approach showed both high reliabilities and very high construct validities. However, the scale purporting to measure students\u27 self-efficacy in relation to their use of the astronomical instrumentation associated with online robotic telescopes was particularly skewed and required further investigation. This current study builds on the previous work and shows how a slight adjustment of the survey items presents an improved and robust scale for measuring self-efficacy
Carbon turnover in the water-soluble protein of the adult human lens.
PurposeHuman eye lenses contain cells that persist from embryonic development. These unique, highly specialized fiber cells located at the core (nucleus) of the lens undergo pseudo-apoptosis to become devoid of cell nuclei and most organelles. Ostensibly lacking in protein transcriptional capabilities, it is currently believed that these nuclear fiber cells owe their extreme longevity to the perseverance of highly stable and densely packed crystallin proteins. Maintaining the structural and functional integrity of lenticular proteins is necessary to sustain cellular transparency and proper vision, yet the means by which the lens actually copes with a lifetime of oxidative stress, seemingly without any capacity for protein turnover and repair, is not completely understood. Although many years of research have been predicated upon the assumption that there is no protein turnover or renewal in nuclear fiber cells, we investigated whether or not different protein fractions possess protein of different ages by using the (14)C bomb pulse.MethodsAdult human lenses were concentrically dissected by gently removing the cell layers in water or shaving to the nucleus with a curved micrometer-controlled blade. The cells were lysed, and the proteins were separated into water-soluble and water-insoluble fractions. The small molecules were removed using 3 kDa spin filters. The (14)C/C was measured in paired protein fractions by accelerator mass spectrometry, and an average age for the material within the sample was assigned using the (14)C bomb pulse.ResultsThe water-insoluble fractions possessed (14)C/C ratios consistent with the age of the cells. In all cases, the water-soluble fractions contained carbon that was younger than the paired water-insoluble fraction.ConclusionsAs the first direct evidence of carbon turnover in protein from adult human nuclear fiber cells, this discovery supports the emerging view of the lens nucleus as a dynamic system capable of maintaining homeostasis in part due to intricate protein transport mechanisms and possibly protein repair. This finding implies that the lens plays an active role in the aversion of age-related nuclear (ARN) cataract
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Materials for phantoms for terahertz pulsed imaging
Phantoms are commonly used in medical imaging for quality assurance, calibration, research and teaching. They may include test patterns or simulations of organs, but in either case a tissue substitute medium is an important component of the phantom. The aim of this work was to identify materials suitable for use as tissue substitutes for the relatively new medical imaging modality terahertz pulsed imaging. Samples of different concentrations of the candidate materials TX151 and napthol green dye were prepared, and measurements made of the frequency-dependent absorption coefficient (0.5 to 1.5 THz) and refractive index (0.5 to 1.0 THz). These results were compared qualitatively with measurements made in a similar way on samples of excised human tissue (skin, adipose tissue and striated muscle). Both materials would be suitable for phantoms where the dominant mechanism to be simulated is absorption (similar to ∼100 cm(-1) at 1 THz) and where simulation of the strength of reflections from boundaries is not important; for example, test patterns for spatial resolution measurements. Only TX151 had a frequency-dependent refractive index close to that of tissue, and could therefore be used to simulate the layered structure of skin, the complexity of microvasculature or to investigate frequency-dependent interference effects that have been noted in terahertz images
Strained Silicon on Silicon by Wafer Bonding and Layer Transfer from Relaxed SiGe Buffer
We report the creation of strained silicon on silicon (SSOS) substrate technology. The method uses a relaxed SiGe buffer as a template for inducing tensile strain in a Si layer, which is then bonded to another Si handle wafer. The original Si wafer and the relaxed SiGe buffer are subsequently removed, thereby transferring a strained-Si layer directly to Si substrate without intermediate SiGe or oxide layers. Complete removal of Ge from the structure was confirmed by cross-sectional transmission electron microscopy as well as secondary ion mass spectrometry. A plan-view transmission electron microscopy study of the strained-Si/Si interface reveals that the lattice-mismatch between the layers is accommodated by an orthogonal array of edge dislocations. This misfit dislocation array, which forms upon bonding, is geometrically necessary and has an average spacing of approximately 40nm, in excellent agreement with established dislocation theory. To our knowledge, this is the first study of a chemically homogeneous, yet lattice-mismatched, interface.Singapore-MIT Alliance (SMA
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