Claudine Drame, Des films pour le dire, reflets de la Shoah au cinéma 1945-1985

L’année 2007 a été marquée par la sortie de deux ouvrages relatifs à la représentation au cinéma du génocide des Juifs d’Europe : celui de Claudine Drame et Le cinéma et la Shoah, un art à l’épreuve de la tragédie du XXe siècle, coordonné par Jean-Michel Frodon aux éditions Cahiers du Cinéma. Ces deux livres partent du même principe : jeter un regard rétrospectif sur des dizaines d’années de représentation des crimes génocidaires nazis au cinéma, en concluant sur la suprématie du film Shoah d..

MHC and MHC-related proteins as pleiotropic signal molecules

Class I molecules of the major histocompatibility complex (MHC) have been studied primarily for their role in presenting peptide antigens to conventional T lymphocytes. An increasing body of evidence suggests that MHC and newly characterized MHC-related molecules have a much more varied function in the body. Many of these molecules are involved in pleiotropic interactions with other proteins, which initiate signal transduction cascades and contribute to cellular and tissue homeostasis

A pathogen with two personalities: death and survival during infection with Chlamydia

https://scholarlycommons.pacific.edu/dugoni-facbooks/1005/thumbnail.jp

MHC and MHC-related proteins as pleiotropic signal molecules

Class I molecules of the major histocompatibility complex (MHC) have been studied primarily for their role in presenting peptide antigens to conventional T lymphocytes. An increasing body of evidence suggests that MHC and newly characterized MHC-related molecules have a much more varied function in the body. Many of these molecules are involved in pleiotropic interactions with other proteins, which initiate signal transduction cascades and contribute to cellular and tissue homeostasis

A pathogen with two personalities: death and survival during infection with Chlamydia

https://scholarlycommons.pacific.edu/dugoni-facbooks/1005/thumbnail.jp

Internal Jugular Vein Tumor Thrombus: A Tricky Question for the Thyroid Surgeon

Internal jugular vein tumor thrombus is an extremely rare condition in thyroid carcinoma, but it does exist. Correlated with greater aggressiveness with a higher incidence of distant metastases at diagnosis and a higher recurrence rate, this important prognostic element should be systematically investigated by ultrasound operators in all patients presenting with thyroid carcinoma. The patient’s follow-up must be careful. This can be a trap that surgeons must look for in their preoperative checklist. We report the case of a 58-year-old woman with an IJV thrombus associated with multiple bone metastases. She underwent successful surgical treatment, and postoperative pathology showed a poorly differentiated follicular carcinoma of the thyroid and a tumor thrombus in the internal jugular vein

Combined Anakinra and Ruxolitinib treatment to rescue extremely ill COVID-19 patients: A pilot study.

International audienceNo abstract availabl

Neutralizing antibody response to SARS-CoV-2 persists 9 months post symptom onset in mild and asymptomatic patients

International audienceObjective: A better understanding of the immune response against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection is critical to predict its dynamics within the general population and its impact on the vaccination strategy. This study assessed the persistence of neutralizing antibody (Nab) activity and SARS-CoV-2 serology in serum samples of mild and asymptomatic patients 9 months post symptom onset (PSO) in a primary care context among immunocompetent adults. Methods: A longitudinal cohort of crew members (CMs) exposed to coronavirus disease 2019 (COVID-19) during an outbreak of SARS-CoV-2 on the French aircraft carrier 'Charles de Gaulle' in April 2020 was created. CMs infected with COVID-19 and with positive serology at the end of quarantine were tested 9 months PSO. Samples were collected 18 and 280 days PSO. For each patient, both serology and serum viral neutralizing activity were performed. Results: In total, 86 CMs were analysed. Samples were collected 18 and 280 days PSO. The seroconversion rates were 100% and 93% (82/86) at 18 and 280 days PSO, respectively, and 72.7% of patients exhibited persistent Nab activity at 9 months, regardless of disease severity. Conclusion: Nab activity persists for up to 9 months following asymptomatic/mild COVID-19 among young adults, regardless of serological results