David Chism in a Faculty Recital

This is the program for the faculty recital featuring trumpet player David Chism and pianist Jane Chu. Trumpet player Ross Grant and organist Dr. Jack W. Jones also performed. This recital took place on April 29, 1976, in the Mabee Fine Arts Center Recital Hall

David Chism and Paul Hammond in a Faculty Recital

This is the program for the faculty recital featuring trumpet player David Chism and bass-baritone Dr. Paul Hammond. Pianist Dr. Russell Hodges assisted the performance. This recital took place on October 28, 1980, in the Mabee Fine Arts Center Recital Hall

Mechanisms of acquired resistance to androgen receptor targeting drugs in castration-resistant prostate cancer

After initial response to androgen receptor targeting drugs abiraterone or enzalutamide, most patients develop progressive disease and therefore, castration resistant prostate cancer (CRPC) remains a terminal disease. Multiple mechanisms underlying acquired resistance have been postulated. Intratumoral androgen synthesis may resume after abiraterone treatment. A point mutation in the ligand binding domain of androgen receptor may confer resistance to enzalutamide. Emergence of androgen receptor splice variants lacking the ligand binding domain may mediate resistance to abiraterone and enzalutamide. Steroid receptors such as glucocorticoid receptor may substitute for androgen receptor. Drugs with novel mechanisms of action or combination therapy, along with biomarkers for patient selection, may be needed to improve the therapy of CRPC

Assessment of Regional Variability in COVID-19 Outcomes Among Patients With Cancer in the United States.

Importance: The COVID-19 pandemic has had a distinct spatiotemporal pattern in the United States. Patients with cancer are at higher risk of severe complications from COVID-19, but it is not well known whether COVID-19 outcomes in this patient population were associated with geography. Objective: To quantify spatiotemporal variation in COVID-19 outcomes among patients with cancer. Design, Setting, and Participants: This registry-based retrospective cohort study included patients with a historical diagnosis of invasive malignant neoplasm and laboratory-confirmed SARS-CoV-2 infection between March and November 2020. Data were collected from cancer care delivery centers in the United States. Exposures: Patient residence was categorized into 9 US census divisions. Cancer center characteristics included academic or community classification, rural-urban continuum code (RUCC), and social vulnerability index. Main Outcomes and Measures: The primary outcome was 30-day all-cause mortality. The secondary composite outcome consisted of receipt of mechanical ventilation, intensive care unit admission, and all-cause death. Multilevel mixed-effects models estimated associations of center-level and census division-level exposures with outcomes after adjustment for patient-level risk factors and quantified variation in adjusted outcomes across centers, census divisions, and calendar time. Results: Data for 4749 patients (median [IQR] age, 66 [56-76] years; 2439 [51.4%] female individuals, 1079 [22.7%] non-Hispanic Black individuals, and 690 [14.5%] Hispanic individuals) were reported from 83 centers in the Northeast (1564 patients [32.9%]), Midwest (1638 [34.5%]), South (894 [18.8%]), and West (653 [13.8%]). After adjustment for patient characteristics, including month of COVID-19 diagnosis, estimated 30-day mortality rates ranged from 5.2% to 26.6% across centers. Patients from centers located in metropolitan areas with population less than 250 000 (RUCC 3) had lower odds of 30-day mortality compared with patients from centers in metropolitan areas with population at least 1 million (RUCC 1) (adjusted odds ratio [aOR], 0.31; 95% CI, 0.11-0.84). The type of center was not significantly associated with primary or secondary outcomes. There were no statistically significant differences in outcome rates across the 9 census divisions, but adjusted mortality rates significantly improved over time (eg, September to November vs March to May: aOR, 0.32; 95% CI, 0.17-0.58). Conclusions and Relevance: In this registry-based cohort study, significant differences in COVID-19 outcomes across US census divisions were not observed. However, substantial heterogeneity in COVID-19 outcomes across cancer care delivery centers was found. Attention to implementing standardized guidelines for the care of patients with cancer and COVID-19 could improve outcomes for these vulnerable patients

A critical analysis of the small business assistance programs of the Department of Defense.

Small business is an institution that has long been in the national spotlight. It ranks close to motherhood and apple pie as standing for what is good in America. Or in the words of one writer, "One of the most sacred of the current sacred cows on the national political scene is that segment of the American enterprise termed 'small business'."http://archive.org/details/criticalanalysis00chi

Right Turn in Albuquerque: Barelas Central Market Terminal

Thesis (Master's)--University of Washington, 2013Author V.B. Price considers Albuquerque, New Mexico, a tributary city; it "connects with mainstream America, but its sources remain in the hinterlands ." The city itself is an amalgamation of historic Southwest forms and identities overrun with decades of postwar pragmatic attempts at maximizing Albuquerque's national relevance while importing the decentralized automobile culture of California. In many ways, Albuquerque is a perfect laboratory city for studying the effects regional identity struggling against place-less suburban expansion, as the "hinterlands" of the Rio Grande basin offer identity, security, and longevity in the form of cuisine and agricultural legacy. This thesis is an analysis of Albuquerque's genus loci; which is rooted deeply in the history and culture of the region. It is from this series of resilient identities that this thesis seeks to posit that food, and the Rio Grande Foodshed, could be a link to reaffirming regional identity and reinforcing local economic ties between the city and the agricultural lands surrounding it. The current access and resilience of the regional agricultural foodshed and urban identity of Albuquerque could be enhanced with the presence of a Central Market Terminal program; this type of program would allow for a multiplicity of economic interactions to occur within the region, not just on the farmer's market scale, but potentially allowing a greater degree of accessibility to the food needs of Albuquerque and New Mexic

David Chism in a Senior Trumpet Recital

This is the program for the senior trumpet recital of David Chism. Pianist Martha Lancaster, organist Sally McCarty, and the Ouachita University Brass Quintet accompanied. The recital took place on November 27, 1973, in Mitchell Hall Auditorium

‘We aim at nothing less than the whole world’: The Seventh-day Adventist Church’s Missionary Enterprise and the General Conference Secretariat, 1863–2019

The subject of this book is how the Seventh-day Adventist Church organized for missionary purposes, in order to carry the gospel to the world, and the structures the denomination put in place to be able to send help to foreign fields. The zeal of pioneer Adventist missionaries and those who came after them is part of the story related in this short book. Yet, it tells not the personal stories of outstanding missionaries, but rather the story of the Seventh-day Adventist Church’s formal efforts to organize global missions; the story told here, then, is the collective, shared, Adventist story.Accordingly, the present goal is more modest than a comprehensive history of the global mission enterprise. It is a study of how the Adventist Church, corporately and collectively, organized itself to manage a global missionary enterprise—and did so with considerable success—before, in the last half century, the very organizational structures set up for that purpose gradually came to focus on other matters. Alongside that shift, not coincidentally the number of missionaries deployed internationally and cross-culturally went into a decades-long decline; recent signs suggest that trend has been arrested, but has it been reversed, or will the 2010s prove to be merely a blip? The future of the Seventh-day Adventist global mission enterprise awaits the decisions of today\u27s and tomorrow\u27s Adventist leaders and members.https://digitalcommons.andrews.edu/books/1288/thumbnail.jp