12,441 research outputs found

    Model selection via Bayesian information capacity designs for generalised linear models

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    The first investigation is made of designs for screening experiments where the response variable is approximated by a generalised linear model. A Bayesian information capacity criterion is defined for the selection of designs that are robust to the form of the linear predictor. For binomial data and logistic regression, the effectiveness of these designs for screening is assessed through simulation studies using all-subsets regression and model selection via maximum penalised likelihood and a generalised information criterion. For Poisson data and log-linear regression, similar assessments are made using maximum likelihood and the Akaike information criterion for minimally-supported designs that are constructed analytically. The results show that effective screening, that is, high power with moderate type I error rate and false discovery rate, can be achieved through suitable choices for the number of design support points and experiment size. Logistic regression is shown to present a more challenging problem than log-linear regression. Some areas for future work are also indicated

    Examining the role of Scotlandā€™s telephone advice service (NHS 24) for managing health in the community : analysis of routinely collected NHS 24 data

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    Date of Acceptance: 15/06/2015 Funding This work was supported by the Chief Scientist Office, ScottishExecutive (grant no. CZH/4/692). Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.Peer reviewedPublisher PD

    Ichthyological Bulletin of the J.L.B. Smith Institute of Ichthyology; No. 37

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    Lethrinops argentea Ahl, L. lethrinus (Gunther) and L. leptodon Regan are re-described and illustrated. An additional new species, L. longipinnis, sharing with the above the possession a steeply sloping, wedge-shaped snout, a slender lower pharyngeal bone and few (9ā€”14) gillrakers is described. The status of L. lunaris Trewavas is discussed.Rhodes University Libraries (Digitisation

    Phosphine Functionalization of GaAs(111)A Surfaces

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    Phosphorus-functionalized GaAs surfaces have been prepared by exposure of Cl-terminated GaAs(111)A surfaces to triethylphosphine (PEt3) or trichlorophosphine (PCl3), or by the direct functionalization of the native-oxide terminated GaAs(111)A surface with PCl3. The presence of phosphorus on each functionalized surface was confirmed by X-ray photoelectron spectroscopy. High-resolution, soft X-ray photoelectron spectroscopy was used to evaluate the As and Ga 3d regions of such surfaces. On PEt3 treated surfaces, the Ga 3d spectra exhibited a bulk Ga peak as well as peaks that were shifted to 0.35, 0.92 and 1.86 eV higher binding energy. These peaks were assigned to residual Cl-terminated Ga surface sites, surficial Ga2O and surficial Ga2O3, respectively. For PCl3-treated surfaces, the Ga 3d spectra displayed peaks ascribable to bulk Ga(As), Ga2O, and Ga2O3, as well as a peak shifted 0.30 eV to higher binding energy relative to the bulk signal. A peak corresponding to Ga(OH)3, observed on the Cl-terminated surface, was absent from all of the phosphine-functionalized surfaces. After reaction of the Cl-terminated GaAs(111)A surface with PCl3 or PEt3, the As 3d spectral region was free of As oxides and As0. Although native oxide-terminated GaAs surfaces were free of As oxides after reaction with PCl3, such surfaces contained detectable amounts of As0. Photoluminescence measurements indicted that phosphine-functionalized surfaces prepared from Cl-terminated GaAs(111)A surfaces had better electrical properties than the native-oxide capped GaAs(111)A surface, while the native-oxide covered surface treated with PCl3 showed no enhancement in PL intensity

    Can I have blood tests to check everything is alright?

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    Patients often request a general check-up with blood tests. In the UK these are often referred to as an MOT, in allusion to the annual motor vehicle check. Some patients may, however, have unrealistic expectations of medical tests1 and underestimate their potential harms. While agreeing to some blood tests can be an easy way out for a busy clinician, it can expose patients to the harms of over-testing and produce extra workload downstream. We provide a framework for navigating these requests constructively, some elements of which are feasible within a 10 minute consultation

    Ichthyological Bulletin of the J.L.B. Smith Institute of Ichthyology; No. 38

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    The group of species considered all have short moderate snouts and a group of slightly to strongly enlarged teeth on the lower pharyngeal bone, the anterior and lateral teeth of which are biscupid, with the posterior cusp turned forwards. Lethrinops parvidens Trewavas, L. aurita (Regan), L. macrophthalmus (Boulenger), L. macrochir (Regan), L.longimanus Trewavas and L. macracanthus Trewavas are re-described, and L. mylodon n. sp. is described, the latter being divided into two geographically seperated sub-species. While L. longimanus and L. macracanthus co-exist with very slight overlap of morphological characters in the south of Lake Malawi, an apparently intermediate population is reported from another part of the Lake.Rhodes University Libraries (Digitisation
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