14 research outputs found
Molecular organization and dynamics of the melatonin MT1 receptor/RGS20/Gi protein complex reveal asymmetry of receptor dimers for RGS and Gi coupling
The concept of pre-formed GPCR–GIP complexes is a hotly debated field. Here, the asymmetric assembly of melatonin receptors, G-protein α subunits and an RGS20 protein in regulating cellular responses has been revealed