Electromagnetic cascades in pulsars

The development of pair photon cascades initiated by high energy electrons above a pulsar polar cap is simulated numerically. The calculation uses the energy of the primary electron, the magnetic field strength, and the period of rotation as parameters and follows the curvature radiation emitted by the primary, the conversion of this radiation e(+) - e(-) pairs in the intense fields, and the quantized synchrotron radiation by the secondary pairs. A recursive technique allows the tracing of an indefinite number of generations using a Monte Carlo method. Gamma ray and pair spectra are calculated for cascades in different parts of the polar cap and with different acceleration models. It is found that synchrotron radiation from secondary pairs makes an important contribution to the gamma ray spectrum above 25 MeV, and that the final gamma ray and pair spectra are insensitive to the height of the accelerating region, as long as the acceleration of the primary electrons is not limited by radiation reaction

Cascade model of gamma-ray bursts: Power-law and annihilation-line components

If, in a neutron star magnetosphere, an electron is accelerated to an energy of 10 to the 11th or 12th power eV by an electric field parallel to the magnetic field, motion of the electron along the curved field line leads to a cascade of gamma rays and electron-positron pairs. This process is believed to occur in radio pulsars and gamma ray burst sources. Results are presented from numerical simulations of the radiation and photon annihilation pair production processes, using a computer code previously developed for the study of radio pulsars. A range of values of initial energy of a primary electron was considered along with initial injection position, and magnetic dipole moment of the neutron star. The resulting spectra was found to exhibit complex forms that are typically power law over a substantial range of photon energy, and typically include a dip in the spectrum near the electron gyro-frequency at the injection point. The results of a number of models are compared with data for the 5 Mar., 1979 gamma ray burst. A good fit was found to the gamma ray part of the spectrum, including the equivalent width of the annihilation line

Pair production in superstrong magnetic fields

The production of electron-positron pairs by single photons in magnetic fields 10 to the twelth power G was investigated in detail for photon energies near threshold as well as for the asymptotic limit of high photon energy. The exact attenuation coefficient, which is derived and then evaluated numerically, is strongly influenced by the discrete energy states of the electron and positron. Near threshold, it exhibits a sawtooth pattern as a function of photon energy, and its value is significantly below that predicted by the asymptotic expression for the attenuation coefficient. The energy distributions of the created pair are computed numerically near threshold and analytic expressions are derived in the asymptotic limit. These results indicate that as field strength and photon energy increase, it becomes increasingly probable for the pair to divide the photon energy unequally. This effect, as well as the threshold behavior of the attenuation coefficient, could have important consequences for pulsar models

Comparative genomics and transcriptomics of Escherichia coli isolates carrying virulence factors of both enteropathogenic and enterotoxigenic E. coli

AbstractEscherichia coli that are capable of causing human disease are often classified into pathogenic variants (pathovars) based on their virulence gene content. However, disease-associated hybrid E. coli, containing unique combinations of multiple canonical virulence factors have also been described. Such was the case of the E. coli O104:H4 outbreak in 2011, which caused significant morbidity and mortality. Among the pathovars of diarrheagenic E. coli that cause significant human disease are the enteropathogenic E. coli (EPEC) and enterotoxigenic E. coli (ETEC). In the current study we use comparative genomics, transcriptomics, and functional studies to characterize isolates that contain virulence factors of both EPEC and ETEC. Based on phylogenomic analysis, these hybrid isolates are more genomically-related to EPEC, but appear to have acquired ETEC virulence genes. Global transcriptional analysis using RNA sequencing, demonstrated that the EPEC and ETEC virulence genes of these hybrid isolates were differentially-expressed under virulence-inducing laboratory conditions, similar to reference isolates. Immunoblot assays further verified that the virulence gene products were produced and that the T3SS effector EspB of EPEC, and heat-labile toxin of ETEC were secreted. These findings document the existence and virulence potential of an E. coli pathovar hybrid that blurs the distinction between E. coli pathovars.</jats:p

TGFβ1 orchestrates renal fibrosis following Escherichia coli pyelonephritis

Renal scarring after pyelonephritis is linked to long-term health risks for hypertension and chronic kidney disease. Androgen exposure increases susceptibility to, and severity of, uropathogenic Escherichia coli (UPEC) pyelonephritis and resultant scarring in both male and female mice, while anti-androgen therapy is protective against severe urinary tract infection (UTI) in these models. This work employed androgenized female C57BL/6 mice to elucidate the molecular mechanisms of post-infectious renal fibrosis and to determine how these pathways are altered by the presence of androgens. We found that elevated circulating testosterone levels primed the kidney for fibrosis by increasing local production of TGFβ1 before the initiation of UTI, altering the ratio of transcription factors Smad2 and Smad3 and increasing the presence of mesenchymal stem cell (MSC)-like cells and Gli1 + activated myofibroblasts, the cells primarily responsible for deposition of scar components. Increased production of TGFβ1 and aberrations in Smad2:Smad3 were maintained throughout the course of infection in the presence of androgen, correlating with renal scarring that was not observed in non-androgenized female mice. Pharmacologic inhibition of TGFβ1 signaling blunted myofibroblast activation. We conclude that renal fibrosis after pyelonephritis is exacerbated by the presence of androgens and involves activation of the TGFβ1 signaling cascade, leading to increases in cortical populations of MSC-like cells and the Gli1 + activated myofibroblasts that are responsible for scarring

F-106B airplane active control landing gear drop test performance

Aircraft dynamic loads and vibrations resulting from landing impact and from runway and taxiway unevenness are recognized as significant factors in causing fatigue damage, dynamic stress on the airframe, crew and passenger discomfort, and reduction of the pilot's ability to control the aircraft during ground operations. One potential method for improving operational characteristics of aircraft on the ground is the application of active control technology to the landing gears to reduce ground loads applied to the airframe. An experimental investigation was conducted on series-hydraulic active control nose gear. The experiments involved testing the gear in both passive and active control modes. Results of this investigation show that a series-hydraulic active control gear is feasible and that such a gear is effective in reducing the loads transmitted by the gear to the airframe during ground operations

Magnetospheric eclipses in the double pulsar system J0737-3039

We argue that eclipses of radio emission from the millisecond pulsar A in the double pulsar system J0737-3039 are due to synchrotron absorption by plasma in the closed field line region of the magnetosphere of its normal pulsar companion B. A's radio beam only illuminates B's magnetosphere for about 10 minutes surrounding the time of eclipse. During this time it heats particles at r\gtrsim 10^9 cm to relativistic energies and enables extra plasma to be trapped by magnetic mirroring. An enhancement of the plasma density by a factor \sim 10^2 is required to match the duration and optical depth of the observed eclipses. The extra plasma might be supplied by a source near B through B\gamma pair creation by energetic photons produced in B's outer gap. Excitation of pairs' gyrational motions by cyclotron absorption of A's radio beam can result in their becoming trapped between conjugate mirror points in B's magnetosphere. Because the trapping efficiency decreases with increasing optical depth, the plasma density enhancement saturates even under steady state illumination. The result is an eclipse with finite, frequency dependent, optical depth. After illumination by A's radio beam ceases, the trapped particles cool and are lost. The entire cycle repeats every orbital period. We speculate that the asymmetries between eclipse ingress and egress result in part from the magnetosphere's evolution toward a steady state when illuminated by A's radio beam. We predict that A's linear polarization will vary with both eclipse phase and B's rotational phase.Comment: 8 pages, 1 figure, submitted to ApJ, references corrected, detectability of reprocessed emission revised, major conclusions unchange

Scattering of Low-Frequency Radiation by a Gyrating Electron

The scattering of electromagnetic radiation by the particle gyrating in an external magnetic field is considered. Particular attention is paid to the low-frequency case, when the frequencies of incident radiation are much less than the electron gyrofrequency. The spectral and polarization features of the scattering cross-section are analyzed in detail. It is found that the scattering transfers the low-frequency photons to high harmonics of the gyrofrequency, into the range of the synchrotron emission of the electron. The total scattering cross-section appears much larger than that for the particle at rest. The problem studied is directly applicable to the radio wave scattering in the magnetosphere of a pulsar. The particles acquire relativistic rotational energies as a result of resonant absorption of the high-frequency radio waves and concurrently scatter the low-frequency radio waves, which are still below the resonance. It is shown that the scattering can affect the radio intensity and polarization at the lowest frequencies and can compete with the resonant absorption in contributing to the low-frequency turnover in the pulsar spectrum. Moreover, the scattering can be an efficient mechanism of the pulsar high-energy emission, in addition to the synchrotron re-emission of the particles. Other astrophysical applications of the scattering by gyrating particles are pointed out as well.Comment: 13 pages, no figures. Accepted for publication in MNRA